Aliases for ACSBG1 Gene
External Ids for ACSBG1 Gene
Previous GeneCards Identifiers for ACSBG1 Gene
The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACSBG1 Gene
ACSBG1 (Acyl-CoA Synthetase Bubblegum Family Member 1) is a Protein Coding gene. Diseases associated with ACSBG1 include ovary adenocarcinoma and malignant ovarian surface epithelial-stromal neoplasm. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include long-chain fatty acid-CoA ligase activity and very long-chain fatty acid-CoA ligase activity. An important paralog of this gene is ACSBG2.
UniProtKB/Swiss-Prot for ACSBG1 Gene
Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.