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Aliases for PCNX Gene

Aliases for PCNX Gene

  • Pecanex Homolog (Drosophila) 2 3
  • PCNXL1 3 4
  • Pecanex-Like 1 (Drosophila) 2
  • Pecanex-Like Protein 1 3
  • Pecanex Homolog 4
  • Pecanex-Like 1 3
  • KIAA0805 4
  • KIAA0995 4
  • Pecanex 3

External Ids for PCNX Gene

Previous HGNC Symbols for PCNX Gene

  • PCNXL1

Previous GeneCards Identifiers for PCNX Gene

  • GC14P068879
  • GC14P065171
  • GC14P069364
  • GC14P070443
  • GC14P071374
  • GC14P051541

Summaries for PCNX Gene

GeneCards Summary for PCNX Gene

PCNX (Pecanex Homolog (Drosophila)) is a Protein Coding gene. An important paralog of this gene is PCNXL4.

Gene Wiki entry for PCNX Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PCNX Gene

Genomics for PCNX Gene

Regulatory Elements for PCNX Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for PCNX Gene

70,907,405 bp from pter
71,115,382 bp from pter
207,978 bases
Plus strand

Genomic View for PCNX Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PCNX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCNX Gene

Proteins for PCNX Gene

  • Protein details for PCNX Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Pecanex-like protein 1
    Protein Accession:
    Secondary Accessions:
    • B2RTR6
    • O94897
    • Q96AI7
    • Q9Y2J9

    Protein attributes for PCNX Gene

    2341 amino acids
    Molecular mass:
    258676 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA76839.1; Type=Frameshift; Positions=41; Evidence={ECO:0000305};

    Alternative splice isoforms for PCNX Gene


neXtProt entry for PCNX Gene

Proteomics data for PCNX Gene at MOPED

Post-translational modifications for PCNX Gene

  • Glycosylation at Asn109, Asn215, Asn348, Asn394, Asn702, Asn852, Asn863, Asn1091, Asn1155, Asn1579, Asn1720, Asn1982, Asn2062, Asn2072, Asn2234, and Asn2260
  • Modification sites at PhosphoSitePlus

Other Protein References for PCNX Gene

No data available for DME Specific Peptides for PCNX Gene

Domains for PCNX Gene

Protein Domains for PCNX Gene


Suggested Antigen Peptide Sequences for PCNX Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the pecanex family.
  • Belongs to the pecanex family.
genes like me logo Genes that share domains with PCNX: view

No data available for Gene Families for PCNX Gene

Function for PCNX Gene

miRNA for PCNX Gene

miRTarBase miRNAs that target PCNX

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PCNX

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for PCNX Gene

Localization for PCNX Gene

Subcellular locations from UniProtKB/Swiss-Prot for PCNX Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for PCNX Gene COMPARTMENTS Subcellular localization image for PCNX gene
Compartment Confidence
plasma membrane 3
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for PCNX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with PCNX: view

Pathways for PCNX Gene

SuperPathways for PCNX Gene

No Data Available

Interacting Proteins for PCNX Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000304192 Q96RV3-PCX1_HUMAN for PCNX Gene via STRING I2D

Gene Ontology (GO) - Biological Process for PCNX Gene


No data available for Pathways by source for PCNX Gene

Transcripts for PCNX Gene

mRNA/cDNA for PCNX Gene

Unigene Clusters for PCNX Gene

Pecanex homolog (Drosophila):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PCNX

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PCNX Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^
SP1: - -
SP3: - -

ExUns: 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38
SP1: -
SP2: - -

Relevant External Links for PCNX Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PCNX Gene

mRNA expression in normal human tissues for PCNX Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PCNX Gene

This gene is overexpressed in Whole Blood (5.6).

Protein differential expression in normal tissues for PCNX Gene

This gene is overexpressed in NK cells (47.1) and Plasma (21.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for PCNX Gene

SOURCE GeneReport for Unigene cluster for PCNX Gene Hs.446559

genes like me logo Genes that share expressions with PCNX: view

Expression partners for PCNX Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for PCNX Gene

Orthologs for PCNX Gene

This gene was present in the common ancestor of animals.

Orthologs for PCNX Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia PCNX 35
  • 90.16 (n)
  • 93.64 (a)
  • 92 (a)
(Canis familiaris)
Mammalia PCNX 35
  • 92.6 (n)
  • 96.05 (a)
  • 96 (a)
(Mus musculus)
Mammalia Pcnx 35
  • 85.8 (n)
  • 91.03 (a)
Pcnx 16
Pcnx 36
  • 91 (a)
(Pan troglodytes)
Mammalia PCNX 35
  • 99.28 (n)
  • 99.12 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Pcnx 35
  • 86.27 (n)
  • 91.24 (a)
(Monodelphis domestica)
Mammalia PCNX 36
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 90 (a)
-- 36
  • 68 (a)
-- 36
  • 91 (a)
(Gallus gallus)
Aves PCNX 35
  • 81.11 (n)
  • 86.77 (a)
  • 86 (a)
(Anolis carolinensis)
Reptilia PCNX 36
  • 84 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100135121 35
  • 76.11 (n)
  • 82.47 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.7316 35
(Danio rerio)
Actinopterygii pcnx 35
  • 66.83 (n)
  • 72.33 (a)
pcnx 36
  • 70 (a)
fruit fly
(Drosophila melanogaster)
Insecta pcx 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea B0511.12 36
  • 32 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13499 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 27 (a)
Species with no ortholog for PCNX:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PCNX Gene

Gene Tree for PCNX (if available)
Gene Tree for PCNX (if available)

Paralogs for PCNX Gene

Paralogs for PCNX Gene

(2) SIMAP similar genes for PCNX Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with PCNX: view

Variants for PCNX Gene

Sequence variations from dbSNP and Humsavar for PCNX Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs16694 -- 71,021,753(-) ATGAG(-/GAG)AATAT intron-variant
rs116016 -- 71,110,763(-) AAGAC(C/G/T)GATCC utr-variant-3-prime
rs221924 -- 71,114,061(-) ACTGA(C/T)GTTAT utr-variant-3-prime
rs221925 -- 71,112,912(-) AAAAA(A/C)AGGCA utr-variant-3-prime
rs221926 -- 71,112,418(-) CAGGG(G/T)TCCTA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for PCNX Gene

Variant ID Type Subtype PubMed ID
esv2590666 CNV Deletion 19546169
esv2229536 CNV Deletion 18987734
esv1004840 CNV Deletion 20482838
esv2748851 CNV Deletion 23290073
nsv85150 CNV Loss 16902084
esv1181559 CNV Deletion 17803354
esv7102 CNV Loss 19470904
nsv1340 CNV Insertion 18451855
esv2660325 CNV Deletion 23128226
esv2748853 CNV Deletion 23290073
esv2748854 CNV Deletion 23290073
esv270654 CNV Insertion 20981092
esv273950 CNV Insertion 20981092
nsv826973 CNV Loss 20364138
esv2392889 CNV Deletion 18987734
esv2748855 CNV Deletion 23290073
esv2675445 CNV Deletion 23128226
esv2496217 CNV Deletion 19546169

Relevant External Links for PCNX Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PCNX Gene

Disorders for PCNX Gene

Relevant External Links for PCNX

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for PCNX Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for PCNX Gene

Publications for PCNX Gene

  1. Physical and transcription map in the region 14q24.3: identification of six novel transcripts. (PMID: 9244429) Roux A.F. … Cox D.W. (Genomics 1997) 2 3
  2. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 9872452) Nagase T. … Ohara O. (DNA Res. 1998) 3 4
  3. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10231032) Nagase T. … Ohara O. (DNA Res. 1999) 3 4
  4. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PMID: 12168954) Nakajima D. … Nagase T. (DNA Res. 2002) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for PCNX Gene

Sources for PCNX Gene

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