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Aliases for PCNX1 Gene

Aliases for PCNX1 Gene

  • Pecanex Homolog 1 (Drosophila) 2 3
  • Pecanex Homolog (Drosophila) 2 5
  • PCNXL1 3 4
  • PCNX 3 5
  • Pecanex-Like 1 (Drosophila) 2
  • Pecanex Homolog 4
  • Pecanex-Like 1 3
  • KIAA0805 4
  • KIAA0995 4
  • Pecanex 3

External Ids for PCNX1 Gene

Previous HGNC Symbols for PCNX1 Gene

  • PCNXL1
  • PCNX

Summaries for PCNX1 Gene

GeneCards Summary for PCNX1 Gene

PCNX1 (Pecanex Homolog 1 (Drosophila)) is a Protein Coding gene. An important paralog of this gene is PCNX4.

Gene Wiki entry for PCNX1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PCNX1 Gene

Genomics for PCNX1 Gene

Regulatory Elements for PCNX1 Gene

Promoters for PCNX1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around PCNX1 on UCSC Golden Path with GeneCards custom track

Genomic Location for PCNX1 Gene

70,907,405 bp from pter
71,115,382 bp from pter
207,978 bases
Plus strand

Genomic View for PCNX1 Gene

Genes around PCNX1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PCNX1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PCNX1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCNX1 Gene

Proteins for PCNX1 Gene

  • Protein details for PCNX1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Pecanex-like protein 1
    Protein Accession:
    Secondary Accessions:
    • B2RTR6
    • O94897
    • Q96AI7
    • Q9Y2J9

    Protein attributes for PCNX1 Gene

    2341 amino acids
    Molecular mass:
    258676 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA76839.1; Type=Frameshift; Positions=41; Evidence={ECO:0000305};

    Alternative splice isoforms for PCNX1 Gene


neXtProt entry for PCNX1 Gene

Proteomics data for PCNX1 Gene at MOPED

Post-translational modifications for PCNX1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PCNX1 Gene

No data available for DME Specific Peptides for PCNX1 Gene

Domains & Families for PCNX1 Gene

Protein Domains for PCNX1 Gene


Suggested Antigen Peptide Sequences for PCNX1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the pecanex family.
  • Belongs to the pecanex family.
genes like me logo Genes that share domains with PCNX1: view

No data available for Gene Families for PCNX1 Gene

Function for PCNX1 Gene

Phenotypes for PCNX1 Gene

GenomeRNAi human phenotypes for PCNX1:
genes like me logo Genes that share phenotypes with PCNX1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for PCNX1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PCNX1 Gene

Localization for PCNX1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PCNX1 Gene

Membrane; Multi-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PCNX1 Gene

Pathways & Interactions for PCNX1 Gene

SuperPathways for PCNX1 Gene

No Data Available

Interacting Proteins for PCNX1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q96RV3-PCX1_HUMAN ENSP00000304192 for PCNX1 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for PCNX1 Gene


No data available for Pathways by source and SIGNOR curated interactions for PCNX1 Gene

Drugs & Compounds for PCNX1 Gene

No Compound Related Data Available

Transcripts for PCNX1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for PCNX1 Gene

No ASD Table

Relevant External Links for PCNX1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PCNX1 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for PCNX1 Gene

Orthologs for PCNX1 Gene

This gene was present in the common ancestor of animals.

Orthologs for PCNX1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia PCNX 35
  • 90.16 (n)
  • 93.64 (a)
  • 92 (a)
(Canis familiaris)
Mammalia PCNX 35
  • 92.6 (n)
  • 96.05 (a)
  • 96 (a)
(Mus musculus)
Mammalia Pcnx 35
  • 85.8 (n)
  • 91.03 (a)
Pcnx 16
Pcnx 36
  • 91 (a)
(Pan troglodytes)
Mammalia PCNX 35
  • 99.28 (n)
  • 99.12 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Pcnx 35
  • 86.27 (n)
  • 91.24 (a)
(Monodelphis domestica)
Mammalia PCNX 36
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 90 (a)
-- 36
  • 68 (a)
-- 36
  • 91 (a)
(Gallus gallus)
Aves PCNX 35
  • 81.11 (n)
  • 86.77 (a)
  • 86 (a)
(Anolis carolinensis)
Reptilia PCNX 36
  • 84 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100135121 35
  • 76.11 (n)
  • 82.47 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.7316 35
(Danio rerio)
Actinopterygii pcnx 35
  • 66.83 (n)
  • 72.33 (a)
pcnx 36
  • 70 (a)
fruit fly
(Drosophila melanogaster)
Insecta pcx 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea B0511.12 36
  • 32 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13499 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 27 (a)
Species with no ortholog for PCNX1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PCNX1 Gene

Gene Tree for PCNX1 (if available)
Gene Tree for PCNX1 (if available)

Paralogs for PCNX1 Gene

Paralogs for PCNX1 Gene

genes like me logo Genes that share paralogs with PCNX1: view

Variants for PCNX1 Gene

Sequence variations from dbSNP and Humsavar for PCNX1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs221924 -- 71,114,061(-) ACTGA(C/T)GTTAT utr-variant-3-prime
rs221925 -- 71,112,912(-) AAAAA(A/C)AGGCA utr-variant-3-prime
rs221926 -- 71,112,418(-) CAGGG(G/T)TCCTA utr-variant-3-prime
rs221927 -- 71,112,024(-) ATATA(C/T)GTATA utr-variant-3-prime
rs16694 -- 71,021,753(-) ATGAG(-/GAG)AATAT intron-variant

Variation tolerance for PCNX1 Gene

Residual Variation Intolerance Score: 0.482% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.91; 59.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PCNX1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PCNX1 Gene

Disorders for PCNX1 Gene

Relevant External Links for PCNX1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PCNX1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PCNX1 Gene

Publications for PCNX1 Gene

  1. The mammalian gene pecanex 1 is differentially expressed during spermatogenesis. (PMID: 15777640) Geisinger A. … Wettstein R. (Biochim. Biophys. Acta 2005) 2 3 67
  2. Physical and transcription map in the region 14q24.3: identification of six novel transcripts. (PMID: 9244429) Roux A.F. … Cox D.W. (Genomics 1997) 2 3
  3. A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus. (PMID: 25130324) Cai D.C. … Hagoort P. (Genes Brain Behav. 2014) 3
  4. Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. (PMID: 22004471) Frank J. … Rietschel M. (Addict Biol 2012) 3
  5. Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene. (PMID: 22881374) Cummings A.C. … Haines J.L. (Ann. Hum. Genet. 2012) 3

Products for PCNX1 Gene

Sources for PCNX1 Gene

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