Aliases for MAPRE3 Gene
External Ids for MAPRE3 Gene
Previous GeneCards Identifiers for MAPRE3 Gene
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MAPRE3 Gene
MAPRE3 (Microtubule-Associated Protein, RP/EB Family, Member 3) is a Protein Coding gene. Diseases associated with MAPRE3 include adenomatous polyposis coli and mature b-cell neoplasm. Among its related pathways are PAK Pathway and Remodeling of Adherens Junctions. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAPRE2.
UniProtKB/Swiss-Prot for MAPRE3 Gene
Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).