Aliases for RRAS2 Gene
External Ids for RRAS2 Gene
Previous GeneCards Identifiers for RRAS2 Gene
This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
GeneCards Summary for RRAS2 Gene
RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2) is a Protein Coding gene. Diseases associated with RRAS2 include ovarian cancer, somatic and breast cancer. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and cAMP signaling pathway. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is HRAS.
UniProtKB/Swiss-Prot for RRAS2 Gene
It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.