External Ids for NID2 Gene
Previous GeneCards Identifiers for NID2 Gene
This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.[provided by RefSeq, Jun 2010]
GeneCards Summary for NID2 Gene
NID2 (Nidogen 2) is a Protein Coding gene. Diseases associated with NID2 include urinary bladder cancer. Among its related pathways are Degradation of the extracellular matrix and Non-integrin membrane-ECM interactions. GO annotations related to this gene include calcium ion binding and collagen binding. An important paralog of this gene is NID1.
UniProtKB/Swiss-Prot for NID2 Gene
Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.