Aliases for SP8 Gene
External Ids for SP8 Gene
The protein encoded by this gene is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for SP8 Gene
SP8 (Sp8 Transcription Factor) is a Protein Coding gene. Diseases associated with SP8 include skin papilloma and bipolar i disorder. Among its related pathways are Disease and Metabolism. An important paralog of this gene is KLF2.
UniProtKB/Swiss-Prot for SP8 Gene
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).