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Aliases for SLC16A9 Gene

Aliases for SLC16A9 Gene

  • Solute Carrier Family 16, Member 9 2 3
  • MCT9 3 4 6
  • Solute Carrier Family 16, Member 9 (Monocarboxylic Acid Transporter 9) 2 3
  • Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 9 2 3
  • Monocarboxylic Acid Transporter 9 2 3
  • Solute Carrier Family 16 Member 9 3 4
  • C10orf36 3 4
  • MCT 9 3 4
  • Chromosome 10 Open Reading Frame 36 2
  • Monocarboxylate Transporter 9 3

External Ids for SLC16A9 Gene

Previous HGNC Symbols for SLC16A9 Gene

  • C10orf36

Previous GeneCards Identifiers for SLC16A9 Gene

  • GC10M060757
  • GC10M060755
  • GC10M061080
  • GC10M061410
  • GC10M055397

Summaries for SLC16A9 Gene

GeneCards Summary for SLC16A9 Gene

SLC16A9 (Solute Carrier Family 16, Member 9) is a Protein Coding gene. GO annotations related to this gene include symporter activity. An important paralog of this gene is SLC16A11.

UniProtKB/Swiss-Prot for SLC16A9 Gene

  • Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).

Gene Wiki entry for SLC16A9 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC16A9 Gene

Genomics for SLC16A9 Gene

Regulatory Elements for SLC16A9 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC16A9 Gene

Start:
59,650,761 bp from pter
End:
59,736,002 bp from pter
Size:
85,242 bases
Orientation:
Minus strand

Genomic View for SLC16A9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC16A9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC16A9 Gene

Proteins for SLC16A9 Gene

  • Protein details for SLC16A9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTY1-MOT9_HUMAN
    Recommended name:
    Monocarboxylate transporter 9
    Protein Accession:
    Q7RTY1
    Secondary Accessions:
    • Q6ZMI2
    • Q9UFH8

    Protein attributes for SLC16A9 Gene

    Size:
    509 amino acids
    Molecular mass:
    55794 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD18743.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for SLC16A9 Gene

Proteomics data for SLC16A9 Gene at MOPED

Post-translational modifications for SLC16A9 Gene

  • Ubiquitination at Lys504
  • Modification sites at PhosphoSitePlus

Other Protein References for SLC16A9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC16A9 Gene

Domains for SLC16A9 Gene

Gene Families for SLC16A9 Gene

Protein Domains for SLC16A9 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC16A9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7RTY1

UniProtKB/Swiss-Prot:

MOT9_HUMAN :
  • Q7RTY1
Family:
  • Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
genes like me logo Genes that share domains with SLC16A9: view

Function for SLC16A9 Gene

Molecular function for SLC16A9 Gene

UniProtKB/Swiss-Prot Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).

Gene Ontology (GO) - Molecular Function for SLC16A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0008028 monocarboxylic acid transmembrane transporter activity IBA --
GO:0015293 symporter activity IEA --
genes like me logo Genes that share ontologies with SLC16A9: view

Animal Model Products

CRISPR Products

miRNA for SLC16A9 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC16A9

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC16A9 Gene

Localization for SLC16A9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC16A9 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC16A9 Gene COMPARTMENTS Subcellular localization image for SLC16A9 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for SLC16A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with SLC16A9: view

Pathways for SLC16A9 Gene

SuperPathways for SLC16A9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SLC16A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015718 monocarboxylic acid transport IBA --
GO:0034220 ion transmembrane transport IBA --
GO:0046415 urate metabolic process IMP 19503597
GO:0055085 transmembrane transport --
genes like me logo Genes that share ontologies with SLC16A9: view

No data available for Pathways by source for SLC16A9 Gene

Transcripts for SLC16A9 Gene

mRNA/cDNA for SLC16A9 Gene

Unigene Clusters for SLC16A9 Gene

Solute carrier family 16, member 9 (monocarboxylic acid transporter 9):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC16A9

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SLC16A9
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC16A9 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b
SP1: - - - - - -
SP2: - - -
SP3: - -
SP4:
SP5: - -
SP6:

Relevant External Links for SLC16A9 Gene

GeneLoc Exon Structure for
SLC16A9
ECgene alternative splicing isoforms for
SLC16A9

Expression for SLC16A9 Gene

mRNA expression in normal human tissues for SLC16A9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC16A9 Gene

This gene is overexpressed in Adrenal Gland (13.4) and Kidney - Cortex (5.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SLC16A9 Gene

SOURCE GeneReport for Unigene cluster for SLC16A9 Gene Hs.499709

genes like me logo Genes that share expressions with SLC16A9: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SLC16A9 Gene

Orthologs for SLC16A9 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC16A9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC16A9 35
  • 99.67 (n)
  • 99.61 (a)
SLC16A9 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC16A9 35
  • 90.75 (n)
  • 91.93 (a)
SLC16A9 36
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC16A9 35
  • 90.83 (n)
  • 91.94 (a)
SLC16A9 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc16a9 35
  • 82.61 (n)
  • 88.34 (a)
Slc16a9 16
Slc16a9 36
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC16A9 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLC16A9 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC687808 35
  • 79.56 (n)
  • 83.73 (a)
chicken
(Gallus gallus)
Aves SLC16A9 35
  • 76.96 (n)
  • 79.21 (a)
SLC16A9 36
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC16A9 36
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485780 35
  • 63.41 (n)
  • 59.53 (a)
zebrafish
(Danio rerio)
Actinopterygii -- 35
slc16a9a 35
  • 58.58 (n)
  • 56.12 (a)
slc16a9a 36
  • 51 (a)
OneToMany
slc16a9b 36
  • 51 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001782 35
  • 46.91 (n)
  • 41.36 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 25 (a)
OneToMany
Species with no ortholog for SLC16A9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC16A9 Gene

ENSEMBL:
Gene Tree for SLC16A9 (if available)
TreeFam:
Gene Tree for SLC16A9 (if available)

Paralogs for SLC16A9 Gene

Selected SIMAP similar genes for SLC16A9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC16A9: view

Variants for SLC16A9 Gene

Sequence variations from dbSNP and Humsavar for SLC16A9 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs715941 -- 59,701,345(-) AGCTC(A/G)GCAGA intron-variant
rs735433 -- 59,670,512(+) CCCAC(A/T)TGGTC intron-variant
rs746228 -- 59,685,415(+) TCTTG(C/T)ATAGC intron-variant
rs753762 -- 59,685,836(-) TAATA(C/T)CTGGC intron-variant
rs753763 -- 59,685,654(-) AAGCC(A/G)CAGGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC16A9 Gene

Variant ID Type Subtype PubMed ID
esv1583704 CNV Deletion 17803354
esv2737462 CNV Deletion 23290073
nsv825405 CNV Loss 20364138
esv2674517 CNV Deletion 23128226
esv2613224 CNV Deletion 19546169
nsv819969 CNV Loss 19587683

Relevant External Links for SLC16A9 Gene

HapMap Linkage Disequilibrium report
SLC16A9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC16A9 Gene

Disorders for SLC16A9 Gene

(2) University of Copenhagen DISEASES for SLC16A9 Gene

Relevant External Links for SLC16A9

Genetic Association Database (GAD)
SLC16A9
Human Genome Epidemiology (HuGE) Navigator
SLC16A9
genes like me logo Genes that share disorders with SLC16A9: view

No data available for UniProtKB/Swiss-Prot for SLC16A9 Gene

Publications for SLC16A9 Gene

  1. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PMID: 12739169) Halestrap A.P. … Meredith D. (Pflugers Arch. 2004) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48
  4. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. (PMID: 19503597) Kolz M. … Gieger C. (PLoS Genet. 2009) 3 48
  5. Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms. (PMID: 19861489) van der Harst P. … Navis G. (Hum. Mol. Genet. 2010) 3 48

Products for SLC16A9 Gene

Sources for SLC16A9 Gene

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