Aliases for ALCAM Gene
External Ids for ALCAM Gene
Previous GeneCards Identifiers for ALCAM Gene
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
GeneCards Summary for ALCAM Gene
ALCAM (Activated Leukocyte Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with ALCAM include appendix adenocarcinoma. Among its related pathways are Developmental Biology and L1CAM interactions. GO annotations related to this gene include receptor binding. An important paralog of this gene is MCAM.
UniProtKB/Swiss-Prot for ALCAM Gene
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system