Aliases for ETV4 Gene
Aliases for ETV4 Gene
External Ids for ETV4 Gene
- HGNC: 3493
- Entrez Gene: 2118
- Ensembl: ENSG00000175832
- OMIM: 600711
- UniProtKB: P43268
Previous GeneCards Identifiers for ETV4 Gene
- GC17U990026
- GC17M043782
- GC17M041615
- GC17M042080
- GC17M038960
- GC17M037370
- GC17M041605
Summaries for ETV4 Gene
GeneCards Summary for ETV4 Gene
ETV4 (ETS Variant 4) is a Protein Coding gene. Diseases associated with ETV4 include Ewing Sarcoma and Extraosseous Ewing's Sarcoma. Among its related pathways are Transcriptional misregulation in cancer and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is ETV1.
UniProtKB/Swiss-Prot for ETV4 Gene
-
Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5[AC]GGA[AT]GT-3.
No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ETV4 Gene
Genomics for ETV4 Gene
Regulatory Elements for ETV4 Gene
Enhancers for ETV4 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ETV4 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ETV4 gene promoter:
Regulatory Element Products
Genomic Location for ETV4 Gene
- Chromosome:
- 17
- Start:
- 43,527,843 bp from pter
- End:
- 43,579,620 bp from pter
- Size:
- 51,778 bases
- Orientation:
- Minus strand
Genomic View for ETV4 Gene
Genes around ETV4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q21.31 by Ensembl
- 17q21.31 by Entrez Gene
- 17q21.31 by HGNC
ETV4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ETV4 Gene
Proteins for ETV4 Gene
-
Protein details for ETV4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P43268-ETV4_HUMAN
- Recommended name:
- ETS translocation variant 4
- Protein Accession:
- P43268
- A8K314
- B7Z5J3
- B7Z9J6
- Q96AW9
Protein attributes for ETV4 Gene
- Size:
- 484 amino acids
- Molecular mass:
- 53938 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAA95991.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ETV4 Gene
Post-translational modifications for ETV4 Gene
- Sumoylated; enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for ETV4 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ETV4
- Novus Biologicals Antibodies for ETV4
-
Abcam antibodies for ETV4
- Invitrogen Antibodies for ETV4
- antibodies-online Antibodies for ETV4: See all 69
- GeneTex ETV4 antibody for ETV4
-
Custom Antibody ServicesProSci Antibodies for ETV4
-
Santa Cruz Biotechnology (SCBT) Antibodies for ETV4
Protein Products
-
OriGene Purified Proteins for ETV4
- Search Origene for MassSpec and Protein Over-expression Lysates for ETV4
- Origene Custom Protein Services for ETV4
- antibodies-online Proteins for ETV4: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ETV4
-
Abcam proteins for ETV4
Assay Products
- antibodies-online Kits for ETV4: See all 1
No data available for DME Specific Peptides for ETV4 Gene
Domains & Families for ETV4 Gene
Gene Families for ETV4 Gene
Protein Domains for ETV4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ETV4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P43268- Family:
-
- Belongs to the ETS family.
Function for ETV4 Gene
Molecular function for ETV4 Gene
- GENATLAS Biochemistry:
- ETS variant gene 4,divergent member of the winged helix-turn-helix superfamily,activating matrix metalloproteinase genes,associated with invasion and metastasis of tumor cell
- UniProtKB/Swiss-Prot Function:
- Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5[AC]GGA[AT]GT-3.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | IDA | 14625302 |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | IBA | -- |
| GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | IC | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | IEA | -- |
Phenotypes for ETV4 Gene
- MGI mutant phenotypes for ETV4:
-
inferred from 3 alleles
- mortality/aging
- behavior/neurological phenotype
- muscle phenotype
- nervous system phenotype
- neoplasm
- reproductive system phenotype
- endocrine/exocrine gland phenotype
- integument phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- embryo phenotype
- renal/urinary system phenotype
- no phenotypic analysis
- GenomeRNAi human phenotypes for ETV4:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ETV4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ETV4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
- Search ViGene Biosciences for ETV4
CRISPR Products
-
OriGene CRISPR knockouts for ETV4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ETV4
- GenScript: Design CRISPR guide RNA sequences for ETV4
miRNA for ETV4 Gene
- miRTarBase miRNAs that target ETV4
miRNA Products
- Search ViGene Biosciences for ETV4
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for ETV4
- Browse OriGene Inhibitory RNA Products For ETV4
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ETV4
- VectorBuilder custom plasmid, inducible vectors for ETV4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ETV4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ETV4
-
ViGene Biosciences adenoviral particle packaged cDNA for ETV4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ETV4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ETV4 Gene
Localization for ETV4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ETV4 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 2 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005634 | nucleus | IBA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005730 | nucleolus | IDA | -- |
Pathways & Interactions for ETV4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transcriptional misregulation in cancer | ||
| 2 | IL-2 Pathway | ||
| 3 | RET signaling | ||
| 4 | CDK-mediated phosphorylation and removal of Cdc6 | ||
| 5 | Signaling by GPCR | ||
Pathways by source for ETV4 Gene
1 BioSystems pathway for ETV4 Gene
3 Reactome pathways for ETV4 Gene
1 KEGG pathway for ETV4 Gene
1 Qiagen pathway for ETV4 Gene
Interacting Proteins for ETV4 Gene
Selected Interacting proteins:
ENSP00000321835
P43268-ETV4_HUMAN
for ETV4 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription from RNA polymerase II promoter | IEA | -- |
| GO:0008045 | motor neuron axon guidance | IEA | -- |
| GO:0010628 | positive regulation of gene expression | IEA | -- |
Transcripts for ETV4 Gene
mRNA/cDNA for ETV4 Gene
- (7) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (154) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ETV4 Gene
- Ets variant 4:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ETV4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ETV4
- GenScript: Design CRISPR guide RNA sequences for ETV4
miRNA Products
- Search ViGene Biosciences for ETV4
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for ETV4
- Browse OriGene Inhibitory RNA Products For ETV4
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ETV4
- VectorBuilder custom plasmid, inducible vectors for ETV4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ETV4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - |
| ExUns: | 15a | · | 15b |
|---|---|---|---|
| SP1: | |||
| SP2: | |||
| SP3: | |||
| SP4: | |||
| SP5: | |||
| SP6: | |||
| SP7: | |||
| SP8: | |||
| SP9: | |||
| SP10: | |||
| SP11: | |||
| SP12: |
Expression for ETV4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Spinal Cord (Nervous System)
- Anterior Latissimus Dorsi Muscle Motor Neurons Caudal Brachial Lateral Motor Division
- Pectoralis Muscle Motor Neurons Caudal Brachial Medial Motor Division
-
Neurons
- Anterior Latissimus Dorsi Muscle Motor Neurons Caudal Brachial Lateral Motor Division
- Pectoralis Muscle Motor Neurons Caudal Brachial Medial Motor Division
mRNA differential expression in normal tissues according to GTEx for ETV4 Gene
This gene is overexpressed in Pituitary (x5.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ETV4 Gene
NURSA nuclear receptor signaling pathways regulating expression of ETV4 Gene:
ETV4SOURCE GeneReport for Unigene cluster for ETV4 Gene:
Hs.434059Evidence on tissue expression from TISSUES for ETV4 Gene
- Intestine(4.5)
- Nervous system(4.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ETV4 Gene
Germ Layers:
- mesoderm
Systems:
- skeleton
Organs:
Head and neck:
- head
- jaw
- mandible
- maxilla
- mouth
- neck
- skull
Thorax:
- chest wall
- clavicle
- rib
- rib cage
- scapula
- sternum
Pelvis:
- pelvis
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs and template standards for ETV4
-
OriGene qPCR primer pairs for ETV4
No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ETV4 Gene
Orthologs for ETV4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ETV4 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | PEA3 35 |
|
OneToOne | |
| ETV4 34 |
|
||||
| cow (Bos Taurus) |
Mammalia | ETV4 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Etv4 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Etv4 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ETV4 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ETV4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ETV4 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ETV4 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | etv4 34 35 |
|
||
| -- 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Ets96B 35 |
|
OneToMany |
- Species where no ortholog for ETV4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ETV4 Gene
Paralogs for ETV4 Gene
(7) SIMAP similar genes for ETV4 Gene using alignment to 4 proteins:
Variants for ETV4 Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000120669 | -- | 43,542,923(+) | CTAGT(A/C)CCTCC | intron-variant | |
| rs1000169011 | -- | 43,540,181(+) | GGTGT(G/T)GTGGC | intron-variant | |
| rs1000198090 | -- | 43,539,997(+) | TAATA(A/C)TTTGG | intron-variant | |
| rs1000352705 | -- | 43,546,194(+) | GGCCG(A/G)GGCGT | upstream-variant-2KB, utr-variant-5-prime | |
| rs1000475188 | -- | 43,534,585(+) | TGTAG(C/T)TTTCC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2761959 | CNV | gain | 21179565 |
| esv3640625 | CNV | gain | 21293372 |
| esv3640630 | CNV | gain | 21293372 |
| nsv1060861 | CNV | gain | 25217958 |
| nsv1065802 | CNV | gain | 25217958 |
| nsv1146669 | OTHER | inversion | 26484159 |
| nsv2059 | CNV | insertion | 18451855 |
| nsv470588 | CNV | gain | 18288195 |
| nsv833453 | CNV | gain+loss | 17160897 |
Residual Variation Intolerance Score:
55.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.11;
51.15% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ETV4 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ETV4 Gene
Disorders for ETV4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ewing sarcoma |
|
|
| extraosseous ewing's sarcoma |
|
|
| epidermodysplasia verruciformis |
|
|
| microphthalmia, isolated 1 |
|
|
| breast cancer |
|
Search ETV4 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ETV4
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ETV4
No data available for UniProtKB/Swiss-Prot and Genatlas for ETV4 Gene
Publications for ETV4 Gene
- Assignment of the ets-related transcription factor E1A-F gene (ETV4) to human chromosome region 17q21. (PMID: 8530053) Isobe M. … Fujinaga K. (Genomics 1995) 2 3 22 64
- Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: a new human member of the ets oncogene family. (PMID: 8441666) Higashino F. … Fujinaga K. (Nucleic Acids Res. 1993) 3 4 22 64
- The E3 ubiquitin ligase complex component COP1 regulates PEA3 group member stability and transcriptional activity. (PMID: 20062082) Baert J.L. … de Launoit Y. (Oncogene 2010) 3 22 64
- Increased PEA3/E1AF and decreased Net/Elk-3, both ETS proteins, characterize human NSCLC progression and regulate caveolin-1 transcription in Calu-1 and NCI-H23 NSCLC cell lines. (PMID: 19483189) Sloan K.A. … Kathuria H. (Carcinogenesis 2009) 3 22 64
- Extracellular signal-regulated kinase mitogen-activated protein kinase signaling initiates a dynamic interplay between sumoylation and ubiquitination to regulate the activity of the transcriptional activator PEA3. (PMID: 19307308) Guo B. … Sharrocks A.D. (Mol. Cell. Biol. 2009) 3 4 64
Products for ETV4 Gene
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- Custom Antibody ServicesOriGene Antibodies for ETV4
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- Novus Biologicals Antibodies for ETV4
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- Abcam antibodies for ETV4
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- Search knockout validated antibodies
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- Invitrogen Antibodies for ETV4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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- antibodies-online Antibodies for ETV4: See all 69
- antibodies-online Kits for ETV4: See all 1
- antibodies-online Proteins for ETV4: See all 6
- Search antibodies-online for peptides
- GeneTex ETV4 antibody for ETV4
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- ViGene Biosciences adenoviral particle packaged cDNA for ETV4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ETV4 gene
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- Search ViGene Biosciences for ETV4
- Santa Cruz Biotechnology (SCBT) Antibodies for ETV4
- Search Santa Cruz Biotechnology (SCBT) for ETV4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ETV4
- Custom Antibody ServicesProSci Antibodies for ETV4
- Search for ETV4 Proteins at ProSci
- Horizon Cell Lines for ETV4
- Cyagen custom Knockout/knockin (KOKI) mouse models for ETV4
- VectorBuilder custom plasmid, inducible vectors for ETV4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ETV4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ETV4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer