Aliases for ETV4 Gene
Aliases for ETV4 Gene
External Ids for ETV4 Gene
- HGNC: 3493
- Entrez Gene: 2118
- Ensembl: ENSG00000175832
- OMIM: 600711
- UniProtKB: P43268
Previous GeneCards Identifiers for ETV4 Gene
- GC17U990026
- GC17M043782
- GC17M041615
- GC17M042080
- GC17M038960
- GC17M037370
- GC17M041605
Summaries for ETV4 Gene
GeneCards Summary for ETV4 Gene
ETV4 (ETS Variant 4) is a Protein Coding gene. Diseases associated with ETV4 include Ewing Sarcoma and Extraosseous Ewing's Sarcoma. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and RET signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is ETV1.
UniProtKB/Swiss-Prot for ETV4 Gene
-
Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5[AC]GGA[AT]GT-3.
Additional gene information for ETV4 Gene
- Monarch Initiative
- Search for ETV4 at DataMed
- Search for ETV4 at HumanCyc
No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ETV4 Gene
Genomics for ETV4 Gene
GeneHancer (GH) Regulatory Elements for ETV4 Gene
Promoters and enhancers for ETV4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ETV4 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ETV4 gene promoter:
Regulatory Element Products
Genomic Locations for ETV4 Gene
Genomic Locations for ETV4 Gene
- chr17:43,527,843-43,579,620
- (GRCh38/hg38)
- Size:
- 51,778 bases
- Orientation:
- Minus strand
- chr17:41,605,211-41,656,988
- (GRCh37/hg19)
Genomic View for ETV4 Gene
Genes around ETV4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q21.31 by Ensembl
- 17q21.31 by Entrez Gene
- 17q21.31 by HGNC
ETV4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ETV4 Gene
Proteins for ETV4 Gene
-
Protein details for ETV4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P43268-ETV4_HUMAN
- Recommended name:
- ETS translocation variant 4
- Protein Accession:
- P43268
- A8K314
- B7Z5J3
- B7Z9J6
- Q96AW9
Protein attributes for ETV4 Gene
- Size:
- 484 amino acids
- Molecular mass:
- 53938 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAA95991.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ETV4 Gene
Post-translational modifications for ETV4 Gene
- Sumoylated; enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
Other Protein References for ETV4 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ETV4
- Novus Biologicals Antibodies for ETV4
-
Abcam antibodies for ETV4
- Invitrogen Antibodies for ETV4
- Search GeneTex for Antibodies for ETV4
-
Custom Antibody ServicesProSci Antibodies for ETV4
-
Santa Cruz Biotechnology (SCBT) Antibodies for ETV4
Protein Products
-
OriGene Purified Proteins for ETV4
- Search Origene for MassSpec and Protein Over-expression Lysates for ETV4
- Origene Custom Protein Services for ETV4
- antibodies-online: Search results for 5 available ETV4 Proteins ranked by validation data
- Compare Top ETV4 Proteins
-
Quality Products:
- Search GeneTex for Proteins for ETV4
-
Abcam proteins for ETV4
Assay Products
- antibodies-online: Search results for available ETV4 related products ranked by validation data
No data available for DME Specific Peptides for ETV4 Gene
Domains & Families for ETV4 Gene
Gene Families for ETV4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ETV4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ETV4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P43268- Family:
-
- Belongs to the ETS family.
Function for ETV4 Gene
Molecular function for ETV4 Gene
- GENATLAS Biochemistry:
- ETS variant gene 4,divergent member of the winged helix-turn-helix superfamily,activating matrix metalloproteinase genes,associated with invasion and metastasis of tumor cell
- UniProtKB/Swiss-Prot Function:
- Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5[AC]GGA[AT]GT-3.
Phenotypes From GWAS Catalog for ETV4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 14625302 |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | IBA | -- |
| GO:0001077 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IC | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | DNA binding transcription factor activity | IEA | -- |
Phenotypes for ETV4 Gene
- MGI mutant phenotypes for ETV4:
-
inferred from 3 alleles
- nervous system phenotype
- muscle phenotype
- mortality/aging
- behavior/neurological phenotype
- neoplasm
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- integument phenotype
- embryo phenotype
- skeleton phenotype
- renal/urinary system phenotype
- no phenotypic analysis
- limbs/digits/tail phenotype
- GenomeRNAi human phenotypes for ETV4:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ETV4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ETV4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
- Search ViGene Biosciences for ETV4
CRISPR Products
-
OriGene CRISPR knockouts for ETV4
- genomics-online: gRNA clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
- Applied Biological Materials CRISPR for ETV4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ETV4
- GenScript: Design CRISPR guide RNA sequences for ETV4
miRNA for ETV4 Gene
- miRTarBase miRNAs that target ETV4
miRNA Products
- Search ViGene Biosciences for ETV4
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ETV4
- Browse OriGene Inhibitory RNA Products For ETV4
- genomics-online: shRNA clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
Clone Products
-
OriGene ORF clones in human for ETV4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ETV4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ETV4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for ETV4
- Applied Biological Materials Clones for ETV4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ETV4
-
ViGene Biosciences adenoviral particle packaged cDNA for ETV4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ETV4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ETV4 Gene
Localization for ETV4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ETV4 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 2 |
| cytoskeleton | 1 |
- Nucleoli (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005730 | nucleolus | IDA | -- |
Pathways & Interactions for ETV4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transcriptional misregulation in cancer | ||
| 2 | IL-2 Pathway | ||
| 3 | RET signaling | ||
| 4 | CDK-mediated phosphorylation and removal of Cdc6 | ||
| 5 | Signaling by GPCR | ||
Pathways by source for ETV4 Gene
1 BioSystems pathway for ETV4 Gene
3 Reactome pathways for ETV4 Gene
1 KEGG pathway for ETV4 Gene
1 Qiagen pathway for ETV4 Gene
Interacting Proteins for ETV4 Gene
Selected Interacting proteins:
ENSP00000321835
P43268-ETV4_HUMAN
for ETV4 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription by RNA polymerase II | IEA | -- |
| GO:0030154 | cell differentiation | IBA | -- |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 24983502 |
Transcripts for ETV4 Gene
mRNA/cDNA for ETV4 Gene
- (7) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (154) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ETV4 Gene
- Ets variant 4:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ETV4
- genomics-online: gRNA clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
- Applied Biological Materials CRISPR for ETV4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ETV4
- GenScript: Design CRISPR guide RNA sequences for ETV4
miRNA Products
- Search ViGene Biosciences for ETV4
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ETV4
- Browse OriGene Inhibitory RNA Products For ETV4
- genomics-online: shRNA clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
Clone Products
-
OriGene ORF clones in human for ETV4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ETV4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ETV4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for ETV4
- Applied Biological Materials Clones for ETV4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - |
| ExUns: | 15a | · | 15b |
|---|---|---|---|
| SP1: | |||
| SP2: | |||
| SP3: | |||
| SP4: | |||
| SP5: | |||
| SP6: | |||
| SP7: | |||
| SP8: | |||
| SP9: | |||
| SP10: | |||
| SP11: | |||
| SP12: |
Expression for ETV4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Spinal Cord (Nervous System)
- Anterior Latissimus Dorsi Muscle Motor Neurons Caudal Brachial Lateral Motor Division
- Pectoralis Muscle Motor Neurons Caudal Brachial Medial Motor Division
-
Neurons
- Anterior Latissimus Dorsi Muscle Motor Neurons Caudal Brachial Lateral Motor Division
- Pectoralis Muscle Motor Neurons Caudal Brachial Medial Motor Division
mRNA differential expression in normal tissues according to GTEx for ETV4 Gene
This gene is overexpressed in Pituitary (x5.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ETV4 Gene
NURSA nuclear receptor signaling pathways regulating expression of ETV4 Gene:
ETV4SOURCE GeneReport for Unigene cluster for ETV4 Gene:
Hs.434059Evidence on tissue expression from TISSUES for ETV4 Gene
- Intestine(4.5)
- Nervous system(4.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ETV4 Gene
Germ Layers:
- mesoderm
Systems:
- skeleton
Organs:
Head and neck:
- head
- jaw
- mandible
- maxilla
- mouth
- neck
- skull
Thorax:
- chest wall
- clavicle
- rib
- rib cage
- scapula
- sternum
Pelvis:
- pelvis
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for ETV4
-
OriGene qPCR primer pairs and template standards for ETV4
No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ETV4 Gene
Orthologs for ETV4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ETV4 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | PEA3 34 |
|
OneToOne | |
| ETV4 33 |
|
||||
| cow (Bos Taurus) |
Mammalia | ETV4 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Etv4 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Etv4 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ETV4 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ETV4 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ETV4 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ETV4 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | etv4 33 34 |
|
||
| -- 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Ets96B 34 |
|
OneToMany |
- Species where no ortholog for ETV4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ETV4 Gene
Paralogs for ETV4 Gene
(7) SIMAP similar genes for ETV4 Gene using alignment to 4 proteins:
Variants for ETV4 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000120669 | -- | 43,542,923(-) | C/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000169011 | -- | 43,540,181(-) | G/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000198090 | -- | 43,539,997(-) | C/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000352705 | -- | 43,546,194(-) | G/A | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant | |
| rs1000475188 | -- | 43,534,585(-) | T/C | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2761959 | CNV | gain | 21179565 |
| esv3640625 | CNV | gain | 21293372 |
| esv3640630 | CNV | gain | 21293372 |
| nsv1060861 | CNV | gain | 25217958 |
| nsv1065802 | CNV | gain | 25217958 |
| nsv1146669 | OTHER | inversion | 26484159 |
| nsv2059 | CNV | insertion | 18451855 |
| nsv470588 | CNV | gain | 18288195 |
| nsv833453 | CNV | gain+loss | 17160897 |
Residual Variation Intolerance Score:
55.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.11;
51.15% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ETV4 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ETV4 Gene
Disorders for ETV4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ewing sarcoma |
|
|
| extraosseous ewing's sarcoma |
|
|
| testicular seminoma |
|
|
| epidermodysplasia verruciformis |
|
|
| microphthalmia, isolated 1 |
|
|
Search ETV4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ETV4
No data available for UniProtKB/Swiss-Prot and Genatlas for ETV4 Gene
Publications for ETV4 Gene
- Assignment of the ets-related transcription factor E1A-F gene (ETV4) to human chromosome region 17q21. (PMID: 8530053) Isobe M … Fujinaga K (Genomics 1995) 2 3 22 58
- Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: a new human member of the ets oncogene family. (PMID: 8441666) Higashino F … Fujinaga K (Nucleic acids research 1993) 3 4 22 58
- The E3 ubiquitin ligase complex component COP1 regulates PEA3 group member stability and transcriptional activity. (PMID: 20062082) Baert JL … de Launoit Y (Oncogene 2010) 3 22 58
- PEA3 activates VEGF transcription in T47D and SKBR3 breast cancer cells. (PMID: 19129951) Hua D … Jin W (Acta biochimica et biophysica Sinica 2009) 3 22 58
- Increased PEA3/E1AF and decreased Net/Elk-3, both ETS proteins, characterize human NSCLC progression and regulate caveolin-1 transcription in Calu-1 and NCI-H23 NSCLC cell lines. (PMID: 19483189) Sloan KA … Kathuria H (Carcinogenesis 2009) 3 22 58
Products for ETV4 Gene
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for ETV4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for ETV4
- VectorBuilder custom plasmid, inducible vectors for ETV4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ETV4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for ETV4
- antibodies-online: Search results for 75 available ETV4 Antibodies ranked by validation data
- Compare Top ETV4 Antibodies
- antibodies-online: Search results for available ETV4 related products ranked by validation data
- antibodies-online: Search results for 5 available ETV4 Proteins ranked by validation data
- Compare Top ETV4 Proteins
- Quality Products:
- Search GeneTex for Antibodies for ETV4
- Search GeneTex for Proteins for ETV4
- ViGene Biosciences adenoviral particle packaged cDNA for ETV4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ETV4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ETV4 gene
- Search ViGene Biosciences for ETV4
- Santa Cruz Biotechnology (SCBT) Antibodies for ETV4
- Search Santa Cruz Biotechnology (SCBT) for ETV4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ETV4
- Custom Antibody ServicesProSci Antibodies for ETV4
- Search for ETV4 Proteins at ProSci
- Horizon Cell Lines for ETV4
- genomics-online: cdna clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
- orf clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
- genomics-online: gRNA clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
- genomics-online: primer clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
- genomics-online: shRNA clones - Search results for 101 available ETV4 gene related products
- Overview of 101 available ETV4 gene related products
Sources for ETV4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew