Aliases for ETS2 Gene
External Ids for ETS2 Gene
Previous GeneCards Identifiers for ETS2 Gene
This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
GeneCards Summary for ETS2 Gene
ETS2 (V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 2) is a Protein Coding gene. Diseases associated with ETS2 include frey syndrome and star syndrome. Among its related pathways are Ras signaling pathway and ERK Signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is ETV2.
UniProtKB/Swiss-Prot for ETS2 Gene
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.