Aliases for ETS2 Gene
- ETS Proto-Oncogene 2, Transcription Factor 2 3
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 2 2 3 5
- V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (Avian) 2
- V-Ets Avian Erythroblastosis Virus E2 Oncogene Homolog 2 3
- V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 3
- Oncogene ETS-2 3
- ETS2IT1 3
External Ids for ETS2 Gene
Previous GeneCards Identifiers for ETS2 Gene
This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
GeneCards Summary for ETS2 Gene
ETS2 (ETS Proto-Oncogene 2, Transcription Factor) is a Protein Coding gene. Diseases associated with ETS2 include choriocarcinoma and down syndrome. Among its related pathways are Dorso-ventral axis formation and HTLV-I infection. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is ETV2.
UniProtKB/Swiss-Prot for ETS2 Gene
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.