Aliases for ETS2 Gene
External Ids for ETS2 Gene
Previous GeneCards Identifiers for ETS2 Gene
This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
GeneCards Summary for ETS2 Gene
ETS2 (V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 2) is a Protein Coding gene. Diseases associated with ETS2 include frey syndrome. Among its related pathways are Ras signaling pathway and ERK Signaling. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and glucocorticoid receptor binding. An important paralog of this gene is ETV2.
UniProtKB/Swiss-Prot for ETS2 Gene
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.