Aliases for ETFB Gene
External Ids for ETFB Gene
Previous GeneCards Identifiers for ETFB Gene
This gene encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ETFB Gene
ETFB (Electron Transfer Flavoprotein Beta Subunit) is a Protein Coding gene. Diseases associated with ETFB include Glutaric Acidemia Iic and Multiple Acyl-Coa Dehydrogenation Deficiency, Severe Neonatal Type. Among its related pathways are Metabolism of proteins and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include electron carrier activity.
UniProtKB/Swiss-Prot for ETFB Gene
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).