Aliases for ETFB Gene
External Ids for ETFB Gene
Previous GeneCards Identifiers for ETFB Gene
This gene encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ETFB Gene
ETFB (Electron-Transfer-Flavoprotein, Beta Polypeptide) is a Protein Coding gene. Diseases associated with ETFB include multiple acyl-coa dehydrogenation deficiency, mild type and multiple acyl-coa dehydrogenation deficiency, severe neonatal type. Among its related pathways are Signaling by GPCR and Metabolism. GO annotations related to this gene include electron carrier activity.
UniProtKB/Swiss-Prot for ETFB Gene
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)