Aliases for ESRRB Gene
External Ids for ESRRB Gene
Previous HGNC Symbols for ESRRB Gene
Previous GeneCards Identifiers for ESRRB Gene
This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. [provided by RefSeq, Jul 2008]
GeneCards Summary for ESRRB Gene
ESRRB (Estrogen Related Receptor Beta) is a Protein Coding gene. Diseases associated with ESRRB include deafness, autosomal recessive 35 and dfnb35 nonsyndromic hearing loss and deafness. Among its related pathways are Gene Expression and Signaling pathways regulating pluripotency of stem cells. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription factor binding. An important paralog of this gene is AR.
UniProtKB/Swiss-Prot for ESRRB Gene
Nuclear receptor, may regulate ESR1 transcriptional activity. Induces the expression of PERM1 in the skeletal muscle.
Estrogen controls many cellular processes including growth, differentiation and function of the reproductive system. Estrogen is also responsible for the growth and maintenance of the skeleton and the normal function of the cardiovascular and nervous systems.