Aliases for AHSG Gene
External Ids for AHSG Gene
Previous GeneCards Identifiers for AHSG Gene
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008]
GeneCards Summary for AHSG Gene
AHSG (Alpha-2-HS-Glycoprotein) is a Protein Coding gene. Diseases associated with AHSG include uremia and liver cirrhosis. Among its related pathways are Glucose / Energy Metabolism and Signaling by BMP. GO annotations related to this gene include cysteine-type endopeptidase inhibitor activity and kinase inhibitor activity. An important paralog of this gene is FETUB.
UniProtKB/Swiss-Prot for AHSG Gene
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions