Aliases for ARID2 Gene
External Ids for ARID2 Gene
Previous GeneCards Identifiers for ARID2 Gene
ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 [PubMed 15985610]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ARID2 Gene
ARID2 (AT-Rich Interaction Domain 2) is a Protein Coding gene. Diseases associated with ARID2 include Urethra Adenocarcinoma and Urethra Clear Cell Adenocarcinoma. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Chromatin organization. GO annotations related to this gene include binding.
UniProtKB/Swiss-Prot for ARID2 Gene
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.