Aliases for EIF1AX Gene
External Ids for EIF1AX Gene
Previous Symbols for EIF1AX Gene
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]
GeneCards Summary for EIF1AX Gene
EIF1AX (Eukaryotic Translation Initiation Factor 1A, X-Linked) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include translation initiation factor activity and translation factor activity, RNA binding. An important paralog of this gene is EIF1AY.
UniProtKB/Swiss-Prot for EIF1AX Gene
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits