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Aliases for DGUOK Gene

Aliases for DGUOK Gene

  • Deoxyguanosine Kinase 2 3 5
  • DGK 3 4
  • Deoxyguanosine Kinase, Mitochondrial 3
  • EC 2.7.1.113 4
  • MTDPS3 3
  • PEOB4 3
  • NCPH 3

External Ids for DGUOK Gene

Previous GeneCards Identifiers for DGUOK Gene

  • GC02P074291
  • GC02P074111
  • GC02P074128
  • GC02P074065
  • GC02P074153
  • GC02P073889

Summaries for DGUOK Gene

Entrez Gene Summary for DGUOK Gene

  • In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for DGUOK Gene

DGUOK (Deoxyguanosine Kinase) is a Protein Coding gene. Diseases associated with DGUOK include Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Recessive 4 and Mitochondrial Dna Depletion Syndrome 3. Among its related pathways are superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis and Metabolism. Gene Ontology (GO) annotations related to this gene include nucleoside kinase activity and deoxyguanosine kinase activity. An important paralog of this gene is DCK.

UniProtKB/Swiss-Prot for DGUOK Gene

  • Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.

Gene Wiki entry for DGUOK Gene

Additional gene information for DGUOK Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DGUOK Gene

Genomics for DGUOK Gene

GeneHancer (GH) Regulatory Elements for DGUOK Gene

Promoters and enhancers for DGUOK Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I073925 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 550.8 +0.2 207 3.5 HDGF PKNOX1 SMAD1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 IRF4 DGUOK ACTG2 STAMBP BOLA3 BOLA3-AS1 DGUOK-AS1 GC02M073969
GH02I073926 Enhancer 0.3 ENCODE 550.8 -1.7 -1677 0.2 TRIM24 DGUOK ACTG2 STAMBP BOLA3 BOLA3-AS1 GC02M073905
GH02I073892 Promoter/Enhancer 1.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.4 -33.1 -33077 3.2 BCOR ZNF664 SRF ZFP36 ZMYM3 MAFK SPI1 ACTG2 STAMBP DGUOK TET3 BOLA3 BOLA3-AS1 TPRKB HTRA2 MOB1A ALMS1
GH02I073962 Enhancer 0.8 dbSUPER 16.3 +36.9 36926 2.4 HDAC1 FOXA2 BATF IRF4 TCF12 SCRT2 ATF7 ETV6 IKZF2 RUNX3 DGUOK BOLA3-AS1 BOLA3 ACTG2 GC02M073969 DGUOK-AS1
GH02I073895 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.4 -30.0 -30031 1.7 ZNF687 CBFB NR2F1 EBF1 REST DPF2 BCL11A TARDBP IKZF1 NBN DGUOK TET3 STAMBP BOLA3 BOLA3-AS1 TPRKB ALMS1-IT1 SMYD5 ACTG2 GC02M073905
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around DGUOK on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the DGUOK gene promoter:

Genomic Locations for DGUOK Gene

Genomic Locations for DGUOK Gene
chr2:73,926,826-73,958,961
(GRCh38/hg38)
Size:
32,136 bases
Orientation:
Plus strand
chr2:74,153,953-74,186,088
(GRCh37/hg19)

Genomic View for DGUOK Gene

Genes around DGUOK on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DGUOK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DGUOK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DGUOK Gene

Proteins for DGUOK Gene

  • Protein details for DGUOK Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16854-DGUOK_HUMAN
    Recommended name:
    Deoxyguanosine kinase, mitochondrial
    Protein Accession:
    Q16854
    Secondary Accessions:
    • P78532
    • Q16759
    • Q4ZG09
    • Q7L1W9
    • Q96BC1

    Protein attributes for DGUOK Gene

    Size:
    277 amino acids
    Molecular mass:
    32056 Da
    Quaternary structure:
    • Homodimer.

    Three dimensional structures from OCA and Proteopedia for DGUOK Gene

    Alternative splice isoforms for DGUOK Gene

neXtProt entry for DGUOK Gene

Post-translational modifications for DGUOK Gene

  • Ubiquitination at Lys129 and posLast=275275

No data available for DME Specific Peptides for DGUOK Gene

Domains & Families for DGUOK Gene

Gene Families for DGUOK Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins

Protein Domains for DGUOK Gene

Suggested Antigen Peptide Sequences for DGUOK Gene

Graphical View of Domain Structure for InterPro Entry

Q16854

UniProtKB/Swiss-Prot:

DGUOK_HUMAN :
  • Belongs to the DCK/DGK family.
Family:
  • Belongs to the DCK/DGK family.
genes like me logo Genes that share domains with DGUOK: view

Function for DGUOK Gene

Molecular function for DGUOK Gene

GENATLAS Biochemistry:
deoxyguanosine kinase,mitochondrial,related to DCK
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + deoxyguanosine = ADP + dGMP.
UniProtKB/Swiss-Prot Function:
Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.

Enzyme Numbers (IUBMB) for DGUOK Gene

Gene Ontology (GO) - Molecular Function for DGUOK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004138 deoxyguanosine kinase activity IDA,TAS 8706825
GO:0005524 ATP binding IEA --
GO:0016301 kinase activity IEA --
GO:0016740 transferase activity IEA --
GO:0019206 nucleoside kinase activity EXP 11427893
genes like me logo Genes that share ontologies with DGUOK: view
genes like me logo Genes that share phenotypes with DGUOK: view

Human Phenotype Ontology for DGUOK Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

miRNA for DGUOK Gene

miRTarBase miRNAs that target DGUOK

Clone Products

  • Addgene plasmids for DGUOK

No data available for Phenotypes From GWAS Catalog , Animal Models , Transcription Factor Targets and HOMER Transcription for DGUOK Gene

Localization for DGUOK Gene

Subcellular locations from UniProtKB/Swiss-Prot for DGUOK Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DGUOK gene
Compartment Confidence
mitochondrion 5
nucleus 5
cytosol 3

Gene Ontology (GO) - Cellular Components for DGUOK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus HDA,IDA 21630459
GO:0005737 cytoplasm IEA --
GO:0005739 mitochondrion TAS 8692979
GO:0005759 mitochondrial matrix TAS --
GO:0005829 cytosol IEA --
genes like me logo Genes that share ontologies with DGUOK: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for DGUOK Gene

Pathways & Interactions for DGUOK Gene

genes like me logo Genes that share pathways with DGUOK: view

Pathways by source for DGUOK Gene

1 BioSystems pathway for DGUOK Gene
2 KEGG pathways for DGUOK Gene

Gene Ontology (GO) - Biological Process for DGUOK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006139 nucleobase-containing compound metabolic process IEA --
GO:0006468 protein phosphorylation IEA --
GO:0008617 guanosine metabolic process TAS 8692979
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process IEA --
GO:0009165 nucleotide biosynthetic process IEA --
genes like me logo Genes that share ontologies with DGUOK: view

No data available for SIGNOR curated interactions for DGUOK Gene

Drugs & Compounds for DGUOK Gene

(17) Drugs for DGUOK Gene - From: DrugBank, FDA Approved Drugs, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Nelarabine Approved, Investigational Pharma Enzyme, substrate Prodrug of ara-G for T-LBL/T-ALL 0
Arranon Approved October 2005 Pharma 0
2'-Deoxyguanosine-5'-Monophosphate Experimental Pharma 0
ATP Investigational Nutra Agonist 0

(16) Additional Compounds for DGUOK Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
deoxyguanosine
  • 2'-Deoxy-Guanosine
  • 2'-Deoxyguanosine
  • 2-Deoxyguanosine
  • 9-(2-Deoxy-b-D-erythro-pentofuranosyl)-Guanine
  • 9-(2-Deoxy-b-D-erythro-pentofuranosyl)guanine
961-07-9
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with DGUOK: view

Transcripts for DGUOK Gene

Unigene Clusters for DGUOK Gene

Deoxyguanosine kinase:
Representative Sequences:

Clone Products

  • Addgene plasmids for DGUOK

Alternative Splicing Database (ASD) splice patterns (SP) for DGUOK Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c · 9d · 9e
SP1: - - - - -
SP2: - - - - - - - - -
SP3: - - - - -
SP4: - - - - - -
SP5: - - - - - -
SP6: - - - - - - - - - -
SP7: - - - - - - -
SP8: - - - - - - - - - - -
SP9: -
SP10: - - - - - - - - - - -
SP11: - - - - - - - -
SP12: - - - - - -
SP13: - - - - - - - - - - - -
SP14: - - - - - - - - - - - - -
SP15: - -
SP16: - - -

Relevant External Links for DGUOK Gene

GeneLoc Exon Structure for
DGUOK
ECgene alternative splicing isoforms for
DGUOK

Expression for DGUOK Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DGUOK Gene

Protein differential expression in normal tissues from HIPED for DGUOK Gene

This gene is overexpressed in Heart (18.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for DGUOK Gene



Protein tissue co-expression partners for DGUOK Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of DGUOK Gene:

DGUOK

SOURCE GeneReport for Unigene cluster for DGUOK Gene:

Hs.469022

mRNA Expression by UniProt/SwissProt for DGUOK Gene:

Q16854-DGUOK_HUMAN
Tissue specificity: Ubiquitous. Highest expression in muscle, brain, liver and lymphoid tissues.

Evidence on tissue expression from TISSUES for DGUOK Gene

  • Nervous system(4.5)
  • Liver(2.3)
  • Muscle(2.3)

Phenotype-based relationships between genes and organs from Gene ORGANizer for DGUOK Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • skeletal muscle
  • skeleton
  • urinary
Organs:
Head and neck:
  • brain
  • ear
  • eye
  • head
  • mouth
  • salivary gland
  • skull
Thorax:
  • breast
  • esophagus
  • heart
Abdomen:
  • abdominal wall
  • adrenal gland
  • kidney
  • liver
  • spleen
  • stomach
Pelvis:
  • testicle
Limb:
  • digit
  • finger
  • foot
  • hand
  • lower limb
  • nail
  • toe
  • upper limb
General:
  • blood
  • blood vessel
  • coagulation system
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal cord
  • sweat gland
genes like me logo Genes that share expression patterns with DGUOK: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for DGUOK Gene

Orthologs for DGUOK Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DGUOK Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DGUOK 33 34
  • 99.4 (n)
dog
(Canis familiaris)
Mammalia DGUOK 33 34
  • 90.13 (n)
cow
(Bos Taurus)
Mammalia DGUOK 33 34
  • 88.21 (n)
rat
(Rattus norvegicus)
Mammalia Dguok 33
  • 80.9 (n)
mouse
(Mus musculus)
Mammalia Dguok 33 16 34
  • 80.51 (n)
oppossum
(Monodelphis domestica)
Mammalia DGUOK 34
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DGUOK 34
  • 65 (a)
OneToOne
chicken
(Gallus gallus)
Aves DGUOK 34
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DGUOK 34
  • 47 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100494916 33
  • 62.62 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.19838 33
zebrafish
(Danio rerio)
Actinopterygii dguok 34 34 33
  • 61.42 (n)
OneToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10372 33
fruit fly
(Drosophila melanogaster)
Insecta dnk 34
  • 30 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G72040 33
  • 46.88 (n)
rice
(Oryza sativa)
Liliopsida Os01g0874100 33
  • 49.9 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 41 (a)
OneToMany
Species where no ortholog for DGUOK was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DGUOK Gene

ENSEMBL:
Gene Tree for DGUOK (if available)
TreeFam:
Gene Tree for DGUOK (if available)

Paralogs for DGUOK Gene

Paralogs for DGUOK Gene

(2) SIMAP similar genes for DGUOK Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with DGUOK: view

Variants for DGUOK Gene

Sequence variations from dbSNP and Humsavar for DGUOK Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs10186730 benign, likely-benign, not specified, Mitochondrial DNA depletion syndrome 73,926,863(+) G/A/T 5_prime_UTR_variant, non_coding_transcript_variant
rs104893630 pathogenic, Mitochondrial DNA-depletion syndrome 3, hepatocerebral 73,946,776(+) C/T coding_sequence_variant, intron_variant, non_coding_transcript_variant, stop_gained
rs104893631 pathogenic, Mitochondrial DNA-depletion syndrome 3, hepatocerebral, Mitochondrial DNA depletion syndrome 3 (MTDPS3) [MIM:251880] 73,946,888(+) G/A coding_sequence_variant, intron_variant, missense_variant, non_coding_transcript_variant
rs104893632 pathogenic, Mitochondrial DNA-depletion syndrome 3, hepatocerebral, Mitochondrial DNA depletion syndrome 3 (MTDPS3) [MIM:251880] 73,957,212(+) G/A coding_sequence_variant, intron_variant, missense_variant, non_coding_transcript_variant
rs104893633 pathogenic, Mitochondrial DNA-depletion syndrome 3, hepatocerebral 73,958,201(+) G/T coding_sequence_variant, missense_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for DGUOK Gene

Variant ID Type Subtype PubMed ID
nsv1011177 CNV gain 25217958

Variation tolerance for DGUOK Gene

Residual Variation Intolerance Score: 57.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.05; 37.61% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for DGUOK Gene

Human Gene Mutation Database (HGMD)
DGUOK
SNPedia medical, phenotypic, and genealogical associations of SNPs for
DGUOK

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DGUOK Gene

Disorders for DGUOK Gene

MalaCards: The human disease database

(11) MalaCards diseases for DGUOK Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search DGUOK in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

DGUOK_HUMAN
  • Mitochondrial DNA depletion syndrome 3 (MTDPS3) [MIM:251880]: A disorder due to mitochondrial dysfunction characterized by onset in infancy of progressive liver failure, hypoglycemia, increased lactate in body fluids, and neurologic abnormalities including hypotonia, encephalopathy, peripheral neuropathy. Affected tissues show both decreased activity of the mtDNA-encoded respiratory chain complexes and mtDNA depletion. {ECO:0000269 PubMed:12205643, ECO:0000269 PubMed:15639197}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Portal hypertension, non-cirrhotic (NCPH) [MIM:617068]: An autosomal recessive disorder characterized by portal hypertension associated with hepatosplenomegaly, in absence of cirrhosis, extrahepatic diseases, and splanchnic venous thrombosis. Portal hypertension is defined by a portal venous system pressure that is at least 5 mm Hg higher than the pressure in the inferior vena cava. High pressure in the portal venous system leads to shunting of blood through vessels that are poorly suited to carrying large blood volumes, resulting in collateral circulation and splenomegaly. NCPH patients show normal liver function. {ECO:0000269 PubMed:17073823, ECO:0000269 PubMed:26874653}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 4 (PEOB4) [MIM:617070]: A form of progressive external ophthalmoplegia, a mitochondrial myopathy characterized by progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. PEOB4 patients manifest clinically variable features including mitochondrial myopathy with or without progressive external ophthalmoplegia, recurrent rhabdomyolysis, and adult-onset lower motor neuron syndrome with mild cognitive impairment. {ECO:0000269 PubMed:23043144}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for DGUOK

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with DGUOK: view

No data available for Genatlas for DGUOK Gene

Publications for DGUOK Gene

  1. Kinetic properties of mutant deoxyguanosine kinase in a case of reversible hepatic mtDNA depletion. (PMID: 17073823) Mousson de Camaret B … Bozon D (The Biochemical journal 2007) 3 4 22 58
  2. Molecular insight into mitochondrial DNA depletion syndrome in two patients with novel mutations in the deoxyguanosine kinase and thymidine kinase 2 genes. (PMID: 15639197) Wang L … Eriksson S (Molecular genetics and metabolism 2005) 3 4 22 58
  3. Mitochondrial DNA depletion and dGK gene mutations. (PMID: 12205643) Salviati L … Vu TH (Annals of neurology 2002) 3 4 22 58
  4. Structural basis for substrate specificities of cellular deoxyribonucleoside kinases. (PMID: 11427893) Johansson K … Eklund H (Nature structural biology 2001) 3 4 22 58
  5. Cloning and expression of human deoxyguanosine kinase cDNA. (PMID: 8692979) Johansson M … Karlsson A (Proceedings of the National Academy of Sciences of the United States of America 1996) 3 4 22 58

Products for DGUOK Gene

Sources for DGUOK Gene

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