Aliases for CNST Gene
External Ids for CNST Gene
Previous HGNC Symbols for CNST Gene
Previous GeneCards Identifiers for CNST Gene
Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010]
GeneCards Summary for CNST Gene
CNST (Consortin, Connexin Sorting Protein) is a Protein Coding gene. Diseases associated with CNST include spinal cord lymphoma. GO annotations related to this gene include phosphatase binding and connexin binding.
UniProtKB/Swiss-Prot for CNST Gene
Required for targeting of connexins to the plasma membrane.