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Aliases for DCC Gene

Aliases for DCC Gene

  • DCC Netrin 1 Receptor 2 3 5
  • Immunoglobulin Superfamily DCC Subclass Member 1 3 4
  • Deleted In Colorectal Carcinoma 2 3
  • Colorectal Cancer Suppressor 3 4
  • Tumor Suppressor Protein DCC 3 4
  • IGDCC1 3 4
  • Immunoglobulin Superfamily, DCC Subclass, Member 1 2
  • Putative Colorectal Tumor Suppressor 3
  • Netrin Receptor DCC 3
  • NTN1R1 3
  • CRC18 3
  • CRCR1 3
  • MRMV1 3

External Ids for DCC Gene

Previous GeneCards Identifiers for DCC Gene

  • GC18P050053
  • GC18P049802
  • GC18P048119
  • GC18P048121
  • GC18P046722

Summaries for DCC Gene

Entrez Gene Summary for DCC Gene

  • This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]

CIViC summary for DCC Gene

GeneCards Summary for DCC Gene

DCC (DCC Netrin 1 Receptor) is a Protein Coding gene. Diseases associated with DCC include Mirror Movements 1 and Colorectal Cancer. Among its related pathways are Developmental Biology and Activation of cAMP-Dependent PKA. GO annotations related to this gene include identical protein binding and transmembrane signaling receptor activity. An important paralog of this gene is NEO1.

UniProtKB/Swiss-Prot for DCC Gene

  • Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

Gene Wiki entry for DCC Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DCC Gene

Genomics for DCC Gene

Regulatory Elements for DCC Gene

Enhancers for DCC Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18G052341 0.9 FANTOM5 ENCODE 9.9 +2.0 2049 0.5 MXI1 HDAC2 SMARCA4 SUZ12 CBX2 RBBP5 EZH2 DCC ENSG00000280098
GH18G052221 0.4 FANTOM5 10.3 -118.4 -118363 0.4 FOS DCC GC18P052320 GC18P052085
GH18G052570 0.3 FANTOM5 1.7 +230.0 229969 0.2 DCC GC18M052306 PIR33677
GH18G052395 0.5 FANTOM5 0.2 +55.6 55551 0.2 MTA2 DPF2 ATF2 TBX21 ENSG00000280098 DCC
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DCC on UCSC Golden Path with GeneCards custom track

Genomic Location for DCC Gene

Chromosome:
18
Start:
52,340,172 bp from pter
End:
53,535,903 bp from pter
Size:
1,195,732 bases
Orientation:
Plus strand

Genomic View for DCC Gene

Genes around DCC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DCC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DCC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DCC Gene

Proteins for DCC Gene

  • Protein details for DCC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P43146-DCC_HUMAN
    Recommended name:
    Netrin receptor DCC
    Protein Accession:
    P43146

    Protein attributes for DCC Gene

    Size:
    1447 amino acids
    Molecular mass:
    158457 Da
    Quaternary structure:
    • Interacts with the cytoplasmic part of UNC5A, UNC5B, UNC5C and probably UNC5D. Interacts with DSCAM. Interacts with PTK2/FAK1 and MAPK1. Interacts with NTN1 (By similarity). Interacts with MYO10. Interacts with CBLN4; this interaction can be competed by NTN1 (By similarity).
    Miscellaneous:
    • Inactivation of DCC due to allelic deletion and/or point mutations is related to lymphatic and hematogenous metastatic tumor dissemination.
    SequenceCaution:
    • Sequence=AAA52175.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAA52177.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAA52179.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAA52180.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for DCC Gene

neXtProt entry for DCC Gene

Post-translational modifications for DCC Gene

  • Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
  • Glycosylation at isoforms=94, isoforms=299, isoforms=318, isoforms=478, isoforms=628, and isoforms=702
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for DCC Gene

Domains & Families for DCC Gene

Suggested Antigen Peptide Sequences for DCC Gene

Graphical View of Domain Structure for InterPro Entry

P43146

UniProtKB/Swiss-Prot:

DCC_HUMAN :
  • Belongs to the immunoglobulin superfamily. DCC family.
Family:
  • Belongs to the immunoglobulin superfamily. DCC family.
genes like me logo Genes that share domains with DCC: view

Function for DCC Gene

Molecular function for DCC Gene

GENATLAS Biochemistry:
netrin-1 receptor,expressed on spinal commissural axons and processing netrin-1 binding activity,inducing attraction in axon guidance through its cytoplasmic tail,inducing apoptosis in the absence of its ligand,homolog of C elegans UNC-40
UniProtKB/Swiss-Prot Function:
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

Gene Ontology (GO) - Molecular Function for DCC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004872 receptor activity IEA --
GO:0004888 transmembrane signaling receptor activity TAS 8861902
GO:0005042 netrin receptor activity IEA --
GO:0005515 protein binding IPI 11527412
genes like me logo Genes that share ontologies with DCC: view
genes like me logo Genes that share phenotypes with DCC: view

Human Phenotype Ontology for DCC Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for DCC Gene

MGI Knock Outs for DCC:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for DCC
  • Applied Biological Materials Clones for DCC

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for DCC Gene

Localization for DCC Gene

Subcellular locations from UniProtKB/Swiss-Prot for DCC Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DCC gene
Compartment Confidence
plasma membrane 5
cytosol 4
extracellular 1
cytoskeleton 1
lysosome 1

Gene Ontology (GO) - Cellular Components for DCC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS --
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DCC: view

Pathways & Interactions for DCC Gene

genes like me logo Genes that share pathways with DCC: view

Gene Ontology (GO) - Biological Process for DCC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001764 neuron migration IEA --
GO:0006915 apoptotic process IEA,TAS 9796814
GO:0007275 multicellular organism development IEA --
GO:0007399 nervous system development IEA --
GO:0007409 axonogenesis TAS 8861902
genes like me logo Genes that share ontologies with DCC: view

No data available for SIGNOR curated interactions for DCC Gene

Drugs & Compounds for DCC Gene

No Compound Related Data Available

Transcripts for DCC Gene

Unigene Clusters for DCC Gene

Deleted in colorectal carcinoma:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for DCC
  • Applied Biological Materials Clones for DCC

Alternative Splicing Database (ASD) splice patterns (SP) for DCC Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22 ^ 23 ^ 24 ^
SP1: -
SP2: -

ExUns: 25 ^ 26 ^ 27 ^ 28 ^ 29
SP1:
SP2:

Relevant External Links for DCC Gene

GeneLoc Exon Structure for
DCC
ECgene alternative splicing isoforms for
DCC

Expression for DCC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DCC Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DCC Gene

This gene is overexpressed in Testis (x18.0) and Brain - Nucleus accumbens (basal ganglia) (x4.8).

Protein differential expression in normal tissues from HIPED for DCC Gene

This gene is overexpressed in Fetal Brain (62.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for DCC Gene



Protein tissue co-expression partners for DCC Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of DCC Gene:

DCC

SOURCE GeneReport for Unigene cluster for DCC Gene:

Hs.162025

mRNA Expression by UniProt/SwissProt for DCC Gene:

P43146-DCC_HUMAN
Tissue specificity: Found in axons of the central and peripheral nervous system and in differentiated cell types of the intestine. Not expressed in colorectal tumor cells that lost their capacity to differentiate into mucus producing cells.

Evidence on tissue expression from TISSUES for DCC Gene

  • Intestine(3.3)
  • Eye(2.6)
  • Nervous system(2.4)

Phenotype-based relationships between genes and organs from Gene ORGANizer for DCC Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • integumentary
  • nervous
  • reproductive
  • skeletal muscle
  • skeleton
  • urinary
Organs:
Head and neck:
  • brain
  • cerebellum
  • head
  • larynx
  • neck
  • vocal cord
Thorax:
  • esophagus
Abdomen:
  • intestine
  • kidney
  • large intestine
  • stomach
Pelvis:
  • anus
  • rectum
  • ureter
  • urethra
  • urinary bladder
  • uterus
Limb:
  • hand
  • upper limb
General:
  • skin
genes like me logo Genes that share expression patterns with DCC: view

Primer Products

Orthologs for DCC Gene

This gene was present in the common ancestor of animals.

Orthologs for DCC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DCC 34 35
  • 99.59 (n)
dog
(Canis familiaris)
Mammalia DCC 34 35
  • 93.01 (n)
oppossum
(Monodelphis domestica)
Mammalia DCC 35
  • 92 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DCC 34
  • 90.92 (n)
mouse
(Mus musculus)
Mammalia Dcc 34 16 35
  • 89.68 (n)
rat
(Rattus norvegicus)
Mammalia Dcc 34
  • 89.53 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 88 (a)
OneToMany
-- 35
  • 79 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia DCC 35
  • 88 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia dcc 34
  • 75.71 (n)
African clawed frog
(Xenopus laevis)
Amphibia dcca-A 34
zebrafish
(Danio rerio)
Actinopterygii CABZ01100973.1 35
  • 78 (a)
OneToMany
dcc 34
  • 66.24 (n)
DCC (2 of 2) 35
  • 62 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta fra 36 35
  • 34 (a)
worm
(Caenorhabditis elegans)
Secernentea unc-40 36 34 35
  • 46.82 (n)
Species where no ortholog for DCC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DCC Gene

ENSEMBL:
Gene Tree for DCC (if available)
TreeFam:
Gene Tree for DCC (if available)

Paralogs for DCC Gene

Variants for DCC Gene

Sequence variations from dbSNP and Humsavar for DCC Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs121912967 Pathogenic, A esophageal carcinoma 52,906,134(+) GCCCA(C/T)GCCAA reference, missense
rs387906555 Pathogenic, A colorectal carcinoma 53,526,629(+) TCTTC(A/C/T)TAAGA reference, missense
VAR_035511 A colorectal cancer sample
rs1057519053 Pathogenic 52,925,310(+) TGTAT(-/A)CCTGT reference, frameshift-variant
rs1057519054 Pathogenic 53,386,061(+) TTATG(G/T)AATCT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for DCC Gene

Variant ID Type Subtype PubMed ID
dgv1605n106 CNV deletion 24896259
dgv1606n106 CNV deletion 24896259
dgv20e198 CNV loss 23635498
dgv5937n54 CNV gain 21841781
dgv5938n54 CNV gain 21841781
dgv616e214 CNV loss 21293372
dgv988e212 CNV loss 25503493
dgv989e212 CNV loss 25503493
esv1007284 CNV loss 20482838
esv1008613 CNV insertion 20482838
esv1010861 CNV loss 20482838
esv1146191 CNV insertion 17803354
esv1388943 CNV deletion 17803354
esv1534314 CNV insertion 17803354
esv1682692 CNV deletion 17803354
esv2108318 CNV deletion 18987734
esv2111490 CNV deletion 18987734
esv22158 CNV loss 19812545
esv2251611 CNV deletion 18987734
esv2252212 CNV deletion 18987734
esv23617 CNV loss 19812545
esv2496857 CNV deletion 19546169
esv2518546 CNV deletion 19546169
esv2592738 CNV deletion 19546169
esv2653679 CNV deletion 19546169
esv2657510 CNV deletion 23128226
esv2666866 CNV deletion 23128226
esv2672905 CNV deletion 23128226
esv2675439 CNV deletion 23128226
esv2675658 CNV deletion 23128226
esv2717105 CNV deletion 23290073
esv2717107 CNV deletion 23290073
esv2717108 CNV deletion 23290073
esv2717109 CNV deletion 23290073
esv2717110 CNV deletion 23290073
esv2717111 CNV deletion 23290073
esv2717112 CNV deletion 23290073
esv2717113 CNV deletion 23290073
esv2717114 CNV deletion 23290073
esv2717115 CNV deletion 23290073
esv2717116 CNV deletion 23290073
esv2717118 CNV deletion 23290073
esv275215 CNV loss 21479260
esv275550 CNV loss 21479260
esv2760474 CNV loss 21179565
esv2762007 CNV loss 21179565
esv2938 CNV loss 18987735
esv3123790 CNV deletion 24192839
esv3124901 CNV deletion 24192839
esv3126012 CNV deletion 24192839
esv3303209 CNV mobile element insertion 20981092
esv3304013 CNV mobile element insertion 20981092
esv3304944 CNV mobile element insertion 20981092
esv3305851 CNV mobile element insertion 20981092
esv3307742 CNV mobile element insertion 20981092
esv3309171 CNV mobile element insertion 20981092
esv3309597 CNV mobile element insertion 20981092
esv3310210 CNV mobile element insertion 20981092
esv3340386 CNV insertion 20981092
esv3349347 CNV insertion 20981092
esv3351798 CNV insertion 20981092
esv3363671 CNV insertion 20981092
esv3366480 CNV insertion 20981092
esv3402786 CNV insertion 20981092
esv3424638 CNV insertion 20981092
esv3438497 CNV insertion 20981092
esv3442100 CNV insertion 20981092
esv3555392 CNV deletion 23714750
esv3555396 CNV deletion 23714750
esv3555405 CNV deletion 23714750
esv3555406 CNV deletion 23714750
esv3583063 CNV loss 25503493
esv3583064 CNV loss 25503493
esv3583065 CNV loss 25503493
esv3583066 CNV loss 25503493
esv3583067 CNV loss 25503493
esv3583068 CNV loss 25503493
esv3583069 CNV loss 25503493
esv3642546 CNV loss 21293372
esv3642549 CNV loss 21293372
esv3642552 CNV loss 21293372
esv3642553 CNV loss 21293372
esv3642555 CNV loss 21293372
esv3642558 CNV loss 21293372
esv3642560 CNV loss 21293372
esv3642565 CNV gain 21293372
esv4836 CNV loss 18987735
esv4954 CNV loss 18987735
esv6032 CNV loss 19470904
esv7831 CNV loss 19470904
esv9355 CNV loss 19470904
esv995021 CNV deletion 20482838
nsv1071463 CNV deletion 25765185
nsv1071464 CNV deletion 25765185
nsv1109144 CNV deletion 24896259
nsv1109145 CNV deletion 24896259
nsv1111157 CNV tandem duplication 24896259
nsv1116273 CNV deletion 24896259
nsv1116274 CNV deletion 24896259
nsv1138627 CNV deletion 24896259
nsv1142237 CNV tandem duplication 24896259
nsv1153882 CNV deletion 26484159
nsv1160524 CNV duplication 26073780
nsv130811 CNV deletion 16902084
nsv131400 CNV deletion 16902084
nsv2308 CNV insertion 18451855
nsv2309 CNV insertion 18451855
nsv2311 CNV insertion 18451855
nsv458076 CNV gain 19166990
nsv458079 CNV loss 19166990
nsv458080 CNV loss 19166990
nsv507872 OTHER sequence alteration 20534489
nsv507873 OTHER sequence alteration 20534489
nsv510457 OTHER sequence alteration 20534489
nsv510741 CNV deletion 20534489
nsv515816 CNV gain 19592680
nsv516994 CNV loss 19592680
nsv521063 CNV loss 19592680
nsv521932 CNV loss 19592680
nsv528217 CNV loss 19592680
nsv576930 CNV loss 21841781
nsv576937 CNV loss 21841781
nsv576938 CNV loss 21841781
nsv576939 CNV loss 21841781
nsv828236 CNV loss 20364138
nsv828237 CNV gain 20364138
nsv828238 CNV loss 20364138
nsv833657 CNV loss 17160897
nsv953545 CNV deletion 24416366
nsv954121 CNV deletion 24416366
nsv954952 CNV deletion 24416366
nsv954957 CNV deletion 24416366

Variation tolerance for DCC Gene

Residual Variation Intolerance Score: 30% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.80; 96.69% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for DCC Gene

Human Gene Mutation Database (HGMD)
DCC
SNPedia medical, phenotypic, and genealogical associations of SNPs for
DCC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DCC Gene

Disorders for DCC Gene

MalaCards: The human disease database

(7) MalaCards diseases for DCC Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
mirror movements 1
  • congenital mirror movements
colorectal cancer
  • colorectal cancer, somatic
corpus callosum agenesis
  • agenesis of the corpus callosum
chudley-mccullough syndrome
  • deafness, bilateral sensorineural, and hydrocephalus due to foramen of monro obstruction
esophageal cancer
  • esophageal cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
Search DCC in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

DCC_HUMAN
  • Mirror movements 1 (MRMV1) [MIM:157600]: A disorder characterized by contralateral involuntary movements that mirror voluntary ones. While mirror movements are occasionally found in young children, persistence beyond the age of 10 is abnormal. Mirror movements occur more commonly in the upper extremities. {ECO:0000269 PubMed:20431009}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for DCC Gene

colorectal carcinoma,deleted in (see TSG18A) in endometrial carcinoma with lymph node metastasis,and in pancreatic carcinomas

Relevant External Links for DCC

Genetic Association Database (GAD)
DCC
Human Genome Epidemiology (HuGE) Navigator
DCC
Tumor Gene Database (TGDB):
DCC
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DCC
genes like me logo Genes that share disorders with DCC: view

Publications for DCC Gene

  1. Identification of a chromosome 18q gene that is altered in colorectal cancers. (PMID: 2294591) Fearon E.R. … Vogelstein B. (Science 1990) 2 3 4 64
  2. Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor. (PMID: 24400119) Haddick P.C. … Gonzalez L.C. (PLoS ONE 2014) 2 3 64
  3. A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population. (PMID: 22318345) Cha P.C. … Nakamura Y. (J. Hum. Genet. 2012) 3 46 64
  4. A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. (PMID: 21529783) Heath A.C. … Montgomery G.W. (Biol. Psychiatry 2011) 3 46 64
  5. Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain. (PMID: 21642953) Hirano Y. … Hakoshima T. (EMBO J. 2011) 3 4 64

Products for DCC Gene

  • Addgene plasmids for DCC

Sources for DCC Gene

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