Aliases for DBP Gene
External Ids for DBP Gene
Previous GeneCards Identifiers for DBP Gene
The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014]
GeneCards Summary for DBP Gene
DBP (D Site Of Albumin Promoter (Albumin D-Box) Binding Protein) is a Protein Coding gene. Diseases associated with DBP include hemophilia b and graves' disease. Among its related pathways are Circadian Clock and Circadian Clock. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is TEF.
UniProtKB/Swiss-Prot for DBP Gene
This transcriptional activator recognizes and binds to the sequence 5-RTTAYGTAAY-3 found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation