External Ids for STRC Gene
Previous HGNC Symbols for STRC Gene
Previous GeneCards Identifiers for STRC Gene
This gene encodes a protein that is associated with the hair bundle of the sensory hair cells in the inner ear. The hair bundle is composed of stiff microvilli called stereocilia and is involved with mechanoreception of sound waves. This gene is part of a tandem duplication on chromosome 15; the second copy is a pseudogene. Mutations in this gene cause autosomal recessive non-syndromic deafness. [provided by RefSeq, Jul 2008]
GeneCards Summary for STRC Gene
STRC (Stereocilin) is a Protein Coding gene. Diseases associated with STRC include deafness-infertility syndrome and dfnb16 nonsyndromic hearing loss and deafness. An important paralog of this gene is OTOA.
UniProtKB/Swiss-Prot for STRC Gene
Essential to the formation of horizontal top connectors between outer hair cell stereocilia.