Aliases for ALDH1L2 Gene
External Ids for ALDH1L2 Gene
Previous GeneCards Identifiers for ALDH1L2 Gene
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
GeneCards Summary for ALDH1L2 Gene
ALDH1L2 (Aldehyde Dehydrogenase 1 Family Member L2) is a Protein Coding gene. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and One carbon pool by folate. GO annotations related to this gene include oxidoreductase activity and aldehyde dehydrogenase (NAD) activity. An important paralog of this gene is ALDH1L1.