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Aliases for CYP2J2 Gene

Aliases for CYP2J2 Gene

  • Cytochrome P450 Family 2 Subfamily J Member 2 2 3 5
  • Cytochrome P450, Subfamily IIJ (Arachidonic Acid Epoxygenase) Polypeptide 2 2 3
  • Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 2 3
  • Arachidonic Acid Epoxygenase 3 4
  • EC 1.14.14.1 4 61
  • CYPIIJ2 3 4
  • Flavoprotein-Linked Monooxygenase 3
  • Microsomal Monooxygenase 3
  • Cytochrome P450 2J2 3
  • CPJ2 3

External Ids for CYP2J2 Gene

Previous GeneCards Identifiers for CYP2J2 Gene

  • GC01M060284
  • GC01M059282
  • GC01M059716
  • GC01M059728
  • GC01M060071
  • GC01M058469

Summaries for CYP2J2 Gene

Entrez Gene Summary for CYP2J2 Gene

  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]

GeneCards Summary for CYP2J2 Gene

CYP2J2 (Cytochrome P450 Family 2 Subfamily J Member 2) is a Protein Coding gene. Diseases associated with CYP2J2 include Clopidogrel Resistance. Among its related pathways are Cytochrome P450 - arranged by substrate type and Arachidonate Epoxygenase / Epoxide Hydrolase. GO annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP2R1.

UniProtKB/Swiss-Prot for CYP2J2 Gene

  • This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.

Gene Wiki entry for CYP2J2 Gene

PharmGKB "VIP" Summary for CYP2J2 Gene

No data available for CIViC summary , Tocris Summary , fRNAdb sequence ontologies and piRNA Summary for CYP2J2 Gene

Genomics for CYP2J2 Gene

Regulatory Elements for CYP2J2 Gene

Enhancers for CYP2J2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G059891 0.5 ENCODE 12.1 +33.8 33805 2.8 HNF4A EGR2 FOXA1 CYP2J2 GC01M059897 GC01P059852
GH01G059966 1.1 Ensembl ENCODE 5.3 -40.5 -40523 1.1 TBP CBX3 ARNT CHAMP1 TCF12 GATA2 GTF2B NCOA1 ZEB2 CREB3 C1orf87 CYP2J2 HOOK1 RN7SL475P GC01M059975
GH01G059926 0.9 ENCODE 6.3 +0.0 1 1.2 ARID4B ZNF76 ZNF48 YY1 GLIS2 ZNF366 EGR2 SP3 SP5 REST CYP2J2 GC01P059903
GH01G059920 0.6 ENCODE 7 +5.0 4967 2.9 CTCF CTBP1 GATA3 SCRT2 CUX1 DPF2 CYP2J2 GC01P059903
GH01G059541 1.4 FANTOM5 Ensembl ENCODE 2.4 +383.1 383135 4.6 ZNF493 ZFP64 RAD21 YY1 THAP11 ZNF654 ZNF362 ZBTB11 CEBPB ZNF426 MYSM1 FGGY LINC01135 CYP2J2 GC01P059473 MIR4711
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CYP2J2 on UCSC Golden Path with GeneCards custom track

Promoters for CYP2J2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000007377 90 1000 ARID4B ZNF76 ZNF48 YY1 GLIS2 ZNF366 EGR2 SP3 SP5 REST

Genomic Location for CYP2J2 Gene

Chromosome:
1
Start:
59,893,308 bp from pter
End:
59,926,790 bp from pter
Size:
33,483 bases
Orientation:
Minus strand

Genomic View for CYP2J2 Gene

Genes around CYP2J2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYP2J2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYP2J2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYP2J2 Gene

Proteins for CYP2J2 Gene

  • Protein details for CYP2J2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51589-CP2J2_HUMAN
    Recommended name:
    Cytochrome P450 2J2
    Protein Accession:
    P51589
    Secondary Accessions:
    • B2RD33
    • Q8TF13

    Protein attributes for CYP2J2 Gene

    Size:
    502 amino acids
    Molecular mass:
    57611 Da
    Cofactor:
    Name=heme; Xref=ChEBI:CHEBI:30413;
    Quaternary structure:
    No Data Available

neXtProt entry for CYP2J2 Gene

Selected DME Specific Peptides for CYP2J2 Gene

P51589:
  • EIDRVIG
  • LFFAGTET
  • VSNIICS
  • PFSIGKR
  • ELFIFFT
  • EERIQEE
  • AGTETTS

Post-translational modifications for CYP2J2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CYP2J2 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for CYP2J2 Gene

Gene Families for CYP2J2 Gene

Suggested Antigen Peptide Sequences for CYP2J2 Gene

Graphical View of Domain Structure for InterPro Entry

P51589

UniProtKB/Swiss-Prot:

CP2J2_HUMAN :
  • Belongs to the cytochrome P450 family.
Family:
  • Belongs to the cytochrome P450 family.
genes like me logo Genes that share domains with CYP2J2: view

Function for CYP2J2 Gene

Molecular function for CYP2J2 Gene

GENATLAS Biochemistry:
cytochrome p450,subfamily 2J catalyzing the NADPH-dependent oxidation of arachidonic acid to form eicosanoids,highly expressed in heart,airway,pancreatic islet cells,intestinal vascular endothelium,involved in the bioactivation of fatty acids
UniProtKB/Swiss-Prot CatalyticActivity:
RH + [reduced NADPH--hemoprotein reductase] + O(2) = ROH + [oxidized NADPH--hemoprotein reductase] + H(2)O.
UniProtKB/Swiss-Prot Function:
This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.

Enzyme Numbers (IUBMB) for CYP2J2 Gene

Gene Ontology (GO) - Molecular Function for CYP2J2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004497 monooxygenase activity TAS --
GO:0005506 iron ion binding IEA --
GO:0008392 arachidonic acid epoxygenase activity TAS --
GO:0008404 arachidonic acid 14,15-epoxygenase activity IDA 11901223
GO:0008405 arachidonic acid 11,12-epoxygenase activity IDA 11901223
genes like me logo Genes that share ontologies with CYP2J2: view
genes like me logo Genes that share phenotypes with CYP2J2: view

Animal Model Products

CRISPR Products

miRNA for CYP2J2 Gene

miRTarBase miRNAs that target CYP2J2

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CYP2J2 Gene

Localization for CYP2J2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYP2J2 Gene

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CYP2J2 gene
Compartment Confidence
extracellular 5
endoplasmic reticulum 5
mitochondrion 2
peroxisome 2
golgi apparatus 2
plasma membrane 1
nucleus 1
cytosol 1
lysosome 1

Gene Ontology (GO) - Cellular Components for CYP2J2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0016020 membrane IEA --
GO:0031090 organelle membrane IEA --
GO:0043231 intracellular membrane-bounded organelle IEA --
genes like me logo Genes that share ontologies with CYP2J2: view

Pathways & Interactions for CYP2J2 Gene

genes like me logo Genes that share pathways with CYP2J2: view

Gene Ontology (GO) - Biological Process for CYP2J2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006690 icosanoid metabolic process TAS 8631948
GO:0006805 xenobiotic metabolic process TAS 11901223
GO:0008016 regulation of heart contraction TAS 8631948
GO:0019373 epoxygenase P450 pathway TAS --
GO:0043651 linoleic acid metabolic process IDA 11901223
genes like me logo Genes that share ontologies with CYP2J2: view

No data available for SIGNOR curated interactions for CYP2J2 Gene

Drugs & Compounds for CYP2J2 Gene

(29) Drugs for CYP2J2 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Astemizole Approved, Withdrawn Pharma Pore Blocker, Enzyme, substrate Orally active, potent H1 antagonist. Also KV11.1 (hERG) channel blocker. 0
Masoprocol Approved Pharma Enzyme, inhibitor 9
Cholecalciferol Approved Nutra Enzyme, substrate Fat-soluble secosteroids 875,869
Apixaban Approved Pharma Enzyme, substrate Factor Xa inhibitor 154
Florbetaben (18F) Approved Pharma Enzyme, substrate 0

(26) Additional Compounds for CYP2J2 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
11,12,15-THETA
  • 11,12,15-TriHETRE
  • 11,12,15-Trihydroxyicosatrienoate
  • 11,12,15-Trihydroxyicosatrienoic acid
  • 11,12,15S-Trihydroxy-5Z,8Z,13E-eicosatrienoate
  • 11,12,15S-Trihydroxy-5Z,8Z,13E-eicosatrienoic acid
11,12-Epoxyeicosatrienoic acid
  • (5Z,8Z,14Z)-11,12-Epoxyeicosa-5,8,14-trienoate
  • (5Z,8Z,14Z)-11,12-Epoxyeicosa-5,8,14-trienoic acid
  • (5Z,8Z,14Z)-11,12-Epoxyicosa-5,8,14-trienoate
  • (5Z,8Z,14Z)-11,12-Epoxyicosa-5,8,14-trienoic acid
  • 10-(3-(2-Octenyl)oxiranyl)-5,8-Decadienoate
81276-02-0
11,14,15-THETA
  • (5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoic acid
  • (5Z,8Z,12E)-11,14,15-Trihydroxyicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-11,14,15-Trihydroxyicosa-5,8,12-trienoic acid
  • 11,14,15-Trihydroxy-5Z,8Z,12E-eicosatrienoate
11H-14,15-EETA
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyeicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyeicosa-5,8,12-trienoic acid
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyicosa-5,8,12-trienoic acid
  • 11-Hydroxy-14,15-EETA
219535-29-2
12,13-EpOME
  • (+/-)-12(13)-epoxy-9Z-octadecenoate
  • (+/-)-12(13)-epoxy-9Z-octadecenoic acid
  • (9Z)-11-(3-pentyloxiran-2-yl)undec-9-enoate
  • (9Z)-11-(3-pentyloxiran-2-yl)undec-9-enoic acid
  • (9Z)-12,13-epoxyoctadecenoate
genes like me logo Genes that share compounds with CYP2J2: view

Transcripts for CYP2J2 Gene

Unigene Clusters for CYP2J2 Gene

Cytochrome P450, family 2, subfamily J, polypeptide 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CYP2J2 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1: - - - -
SP2: - - - - -
SP3:
SP4: - - - - - -
SP5: - - -
SP6: - - -
SP7: -

Relevant External Links for CYP2J2 Gene

GeneLoc Exon Structure for
CYP2J2
ECgene alternative splicing isoforms for
CYP2J2

Expression for CYP2J2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CYP2J2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CYP2J2 Gene

This gene is overexpressed in Heart - Left Ventricle (x8.3), Heart - Atrial Appendage (x6.9), and Liver (x6.2).

Protein differential expression in normal tissues from HIPED for CYP2J2 Gene

This gene is overexpressed in Fetal Liver (18.7), Liver (13.6), Gallbladder (9.3), Fetal heart (7.2), and Heart (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CYP2J2 Gene



Protein tissue co-expression partners for CYP2J2 Gene

NURSA nuclear receptor signaling pathways regulating expression of CYP2J2 Gene:

CYP2J2

SOURCE GeneReport for Unigene cluster for CYP2J2 Gene:

Hs.152096

mRNA Expression by UniProt/SwissProt for CYP2J2 Gene:

P51589-CP2J2_HUMAN
Tissue specificity: Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.

Evidence on tissue expression from TISSUES for CYP2J2 Gene

  • Liver(4.6)
  • Nervous system(4.5)
  • Skin(4.2)
  • Heart(3)
  • Muscle(2.7)
genes like me logo Genes that share expression patterns with CYP2J2: view

Primer Products

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CYP2J2 Gene

Orthologs for CYP2J2 Gene

This gene was present in the common ancestor of animals.

Orthologs for CYP2J2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC456896 34
  • 99.4 (n)
CYP2J2 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CYP2J2 34 35
  • 84.36 (n)
cow
(Bos Taurus)
Mammalia LOC530929 34
  • 82.41 (n)
-- 35
  • 78 (a)
OneToMany
-- 35
  • 76 (a)
OneToMany
-- 35
  • 76 (a)
OneToMany
-- 35
  • 74 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Cyp2j4 34
  • 79.93 (n)
mouse
(Mus musculus)
Mammalia Cyp2j6 34 16 35
  • 78.4 (n)
Cyp2j9 35
  • 73 (a)
OneToMany
Cyp2j13 35
  • 72 (a)
OneToMany
Cyp2j12 35
  • 71 (a)
OneToMany
Cyp2j5 35
  • 70 (a)
OneToMany
Cyp2j7-ps 35
  • 70 (a)
OneToMany
Cyp2j8 35
  • 70 (a)
OneToMany
Cyp2j11 35
  • 68 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 66 (a)
OneToMany
-- 35
  • 65 (a)
OneToMany
-- 35
  • 64 (a)
OneToMany
-- 35
  • 63 (a)
OneToMany
-- 35
  • 63 (a)
OneToMany
-- 35
  • 63 (a)
OneToMany
-- 35
  • 58 (a)
OneToMany
-- 35
  • 57 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia CYP2J2 35
  • 55 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC424729 34
  • 61.08 (n)
-- 35
  • 58 (a)
OneToMany
-- 35
  • 57 (a)
OneToMany
-- 35
  • 57 (a)
OneToMany
-- 35
  • 51 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia CYP2J2 35
  • 54 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496620 34
  • 52.06 (n)
zebrafish
(Danio rerio)
Actinopterygii cyp2p10 34 35
  • 55.62 (n)
cyp2p8 35
  • 51 (a)
OneToMany
cyp2j20 35
  • 50 (a)
OneToMany
cyp2p7 35
  • 50 (a)
OneToMany
cyp2p9 35
  • 50 (a)
OneToMany
cyp2ad2 35
  • 48 (a)
OneToMany
cyp2n13 35
  • 48 (a)
OneToMany
cyp2v1 35
  • 48 (a)
OneToMany
cyp2ad3 35
  • 47 (a)
OneToMany
cyp2ad6 35
  • 46 (a)
OneToMany
cyp2ae1 35
  • 46 (a)
OneToMany
cyp2p6 35
  • 46 (a)
OneToMany
Dr.25426 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1599 34
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012937 34
  • 47.69 (n)
fruit fly
(Drosophila melanogaster)
Insecta Cyp305a1 36 34
  • 45.06 (n)
Cyp18a1 36
  • 33 (a)
Cyp303a1 36
  • 29 (a)
Cyp304a1 36
  • 28 (a)
Cyp307a1 36
  • 27 (a)
worm
(Caenorhabditis elegans)
Secernentea cyp-14A3 34
  • 46.7 (n)
R08F11.3 36
  • 36 (a)
B0304.3 36
  • 35 (a)
B0213.11 36
  • 34 (a)
K09A11.4 36
  • 34 (a)
C41G6.1 36
  • 33 (a)
C49C8.4 36
  • 33 (a)
F41B5.2 36
  • 33 (a)
F41B5.4 36
  • 33 (a)
F41B5.7 36
  • 33 (a)
K05D4.4 36
  • 33 (a)
K09A11.2 36
  • 33 (a)
Y49C4A.9 36
  • 33 (a)
B0213.12 36
  • 32 (a)
B0213.15 36
  • 32 (a)
C12D5.7 36
  • 32 (a)
C45H4.17 36
  • 32 (a)
C45H4.2 36
  • 32 (a)
C50H11.15 36
  • 32 (a)
F41B5.3 36
  • 32 (a)
F42A9.5 36
  • 32 (a)
F44C8.1 36
  • 32 (a)
C34B7.3 36
  • 31 (a)
K07C6.3 36
  • 31 (a)
T09H2.1 36
  • 31 (a)
Y5H2B.6 36
  • 31 (a)
B0213.14 36
  • 30 (a)
K07C6.2 36
  • 30 (a)
B0213.10 36
  • 29 (a)
F14H3.10 36
  • 29 (a)
Species where no ortholog for CYP2J2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CYP2J2 Gene

ENSEMBL:
Gene Tree for CYP2J2 (if available)
TreeFam:
Gene Tree for CYP2J2 (if available)

Paralogs for CYP2J2 Gene

Paralogs for CYP2J2 Gene

genes like me logo Genes that share paralogs with CYP2J2: view

Variants for CYP2J2 Gene

Sequence variations from dbSNP and Humsavar for CYP2J2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000067968 -- 59,894,763(+) GGTAA(C/T)AATAA intron-variant
rs1000343727 -- 59,907,177(+) CCTAG(C/G)GGAGC intron-variant
rs1000353962 -- 59,899,382(+) ATCGA(C/T)CATCA intron-variant
rs1000468891 -- 59,905,479(+) AATAT(A/C)ATCAC intron-variant
rs1000475850 -- 59,925,866(+) GCAGG(A/G)AAACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CYP2J2 Gene

Variant ID Type Subtype PubMed ID
nsv1012703 CNV gain 25217958

Variation tolerance for CYP2J2 Gene

Residual Variation Intolerance Score: 80.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.98; 36.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CYP2J2 Gene

Human Gene Mutation Database (HGMD)
CYP2J2
The Human Cytochrome P450 Allele Nomenclature Database
CYP2J2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CYP2J2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYP2J2 Gene

Disorders for CYP2J2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CYP2J2 Gene - From: GeneCards

Disorder Aliases PubMed IDs
clopidogrel resistance
  • cyp2c19-related poor drug metabolism
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for CYP2J2

Genetic Association Database (GAD)
CYP2J2
Human Genome Epidemiology (HuGE) Navigator
CYP2J2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CYP2J2
genes like me logo Genes that share disorders with CYP2J2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CYP2J2 Gene

Publications for CYP2J2 Gene

  1. The common functional polymorphism -50G>T of the CYP2J2 gene is not associated with ischemic coronary and cerebrovascular events in an urban-based sample of Swedes. (PMID: 19851119) Fava C. … Melander O. (J. Hypertens. 2010) 3 22 46 64
  2. Common variation in cytochrome P450 epoxygenase genes and the risk of incident nonfatal myocardial infarction and ischemic stroke. (PMID: 18496133) Marciante K.D. … Psaty B.M. (Pharmacogenet. Genomics 2008) 3 22 46 64
  3. Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. (PMID: 18769365) Smith H.E. … Totah R.A. (Pharmacogenet. Genomics 2008) 3 22 46 64
  4. Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population. (PMID: 18216721) Zhang L. … Wang D.W. (Pharmacogenet. Genomics 2008) 3 22 46 64
  5. A common polymorphism G-50T in cytochrome P450 2J2 gene is associated with increased risk of essential hypertension in a Russian population. (PMID: 18219097) Polonikov A.V. … Kolesnikova O.E. (Dis. Markers 2008) 3 22 46 64

Products for CYP2J2 Gene

Sources for CYP2J2 Gene

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