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Aliases for CYP2A7 Gene

Aliases for CYP2A7 Gene

  • Cytochrome P450 Family 2 Subfamily A Member 7 2 3 5
  • Cytochrome P450, Subfamily IIA (Phenobarbital-Inducible), Polypeptide 7 2 3
  • Cytochrome P450, Family 2, Subfamily A, Polypeptide 7 2 3
  • Cytochrome P450 IIA4 3 4
  • EC 1.14.14.1 4 61
  • CYPIIA7 3 4
  • Cytochrome P450 2A7 3
  • Cytochrome P450IIA4 3
  • P450-IIA4 3
  • CYP2A 3
  • CPAD 3
  • CPA7 3

External Ids for CYP2A7 Gene

Previous GeneCards Identifiers for CYP2A7 Gene

  • GC19M042020
  • GC19M041773
  • GC19M046002
  • GC19M046018
  • GC19M046020
  • GC19M046073
  • GC19M041350
  • GC19M041381

Summaries for CYP2A7 Gene

Entrez Gene Summary for CYP2A7 Gene

  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

GeneCards Summary for CYP2A7 Gene

CYP2A7 (Cytochrome P450 Family 2 Subfamily A Member 7) is a Protein Coding gene. Among its related pathways are Cytochrome P450 - arranged by substrate type and Metabolism. GO annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP2A6.

UniProtKB/Swiss-Prot for CYP2A7 Gene

  • Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Gene Wiki entry for CYP2A7 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP2A7 Gene

Genomics for CYP2A7 Gene

Regulatory Elements for CYP2A7 Gene

Enhancers for CYP2A7 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G040875 1.3 Ensembl ENCODE dbSUPER 5.8 +7.1 7052 1.4 KLF1 ZNF335 ZNF121 ZFHX2 POLR2A ZNF366 PATZ1 PRDM10 KLF7 KLF8 CYP2G1P CYP2B7P CYP2A7 CYP2A6
GH19G040863 1.5 Ensembl ENCODE dbSUPER 0.4 +18.1 18109 1.6 PKNOX1 ATF1 ARNT FEZF1 TCF12 ZNF121 KLF7 NCOA1 TSHZ1 ZNF518A CYP2F2P EGLN2 CYP2A6 CYP2A7
GH19G040862 1.2 ENCODE dbSUPER 0.4 +19.6 19617 1.0 ATF1 CREB3L1 ZNF493 NFRKB ZNF133 ZNF121 ZNF23 ZNF366 ZSCAN5C SCRT2 SNRPA ENSG00000269843 ENSG00000205041 CCDC97 ITPKC ENSG00000269069 ENSG00000268366 SERTAD3 PSMC4 COQ8B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CYP2A7 on UCSC Golden Path with GeneCards custom track

Genomic Location for CYP2A7 Gene

Chromosome:
19
Start:
40,875,439 bp from pter
End:
40,882,752 bp from pter
Size:
7,314 bases
Orientation:
Minus strand

Genomic View for CYP2A7 Gene

Genes around CYP2A7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYP2A7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYP2A7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYP2A7 Gene

Proteins for CYP2A7 Gene

  • Protein details for CYP2A7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P20853-CP2A7_HUMAN
    Recommended name:
    Cytochrome P450 2A7
    Protein Accession:
    P20853
    Secondary Accessions:
    • Q13121

    Protein attributes for CYP2A7 Gene

    Size:
    494 amino acids
    Molecular mass:
    56425 Da
    Cofactor:
    Name=heme; Xref=ChEBI:CHEBI:30413;
    Quaternary structure:
    No Data Available

neXtProt entry for CYP2A7 Gene

Selected DME Specific Peptides for CYP2A7 Gene

P20853:
  • EIDRVIG
  • DFIAKKVE
  • IDPTFFLSRTVSNVISS
  • EEFSGRG
  • SVMKHLPG
  • LGPRRVVVL
  • LLLMKHP
  • PGPTPLP
  • NQRTLDPNSP
  • AVIHEIQR
  • FIDSFLI
  • EALVDQAE
  • PKGTEVFP
  • GERAKQL
  • PFSIGKR
  • GEGLARME
  • LPFIGNY
  • GKLPPGP
  • EERIQEE
  • DRTKMPY
  • TLRYGFLL

Post-translational modifications for CYP2A7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CYP2A7 Gene

Antibody Products

  • Abcam antibodies for CYP2A7

Domains & Families for CYP2A7 Gene

Gene Families for CYP2A7 Gene

Suggested Antigen Peptide Sequences for CYP2A7 Gene

Graphical View of Domain Structure for InterPro Entry

P20853

UniProtKB/Swiss-Prot:

CP2A7_HUMAN :
  • Belongs to the cytochrome P450 family.
Family:
  • Belongs to the cytochrome P450 family.
genes like me logo Genes that share domains with CYP2A7: view

Function for CYP2A7 Gene

Molecular function for CYP2A7 Gene

GENATLAS Biochemistry:
cytochrome P450,subfamily IIA (phenobarbital-inducible),polypeptide 7
UniProtKB/Swiss-Prot CatalyticActivity:
RH + [reduced NADPH--hemoprotein reductase] + O(2) = ROH + [oxidized NADPH--hemoprotein reductase] + H(2)O.
UniProtKB/Swiss-Prot Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
UniProtKB/Swiss-Prot Induction:
P450 can be induced to high levels in liver and other tissues by various foreign compounds, including drugs, pesticides, and carcinogens.

Enzyme Numbers (IUBMB) for CYP2A7 Gene

Gene Ontology (GO) - Molecular Function for CYP2A7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005506 iron ion binding IEA --
GO:0008392 arachidonic acid epoxygenase activity IBA --
GO:0016491 oxidoreductase activity IEA --
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA --
GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA --
genes like me logo Genes that share ontologies with CYP2A7: view
genes like me logo Genes that share phenotypes with CYP2A7: view

Animal Models for CYP2A7 Gene

MGI Knock Outs for CYP2A7:

Animal Model Products

CRISPR Products

miRNA for CYP2A7 Gene

miRTarBase miRNAs that target CYP2A7

Inhibitory RNA Products

Flow Cytometry Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CYP2A7 Gene

Localization for CYP2A7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYP2A7 Gene

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CYP2A7 gene
Compartment Confidence
endoplasmic reticulum 5
golgi apparatus 2
extracellular 1
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for CYP2A7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0031090 organelle membrane IEA --
genes like me logo Genes that share ontologies with CYP2A7: view

Pathways & Interactions for CYP2A7 Gene

genes like me logo Genes that share pathways with CYP2A7: view

Pathways by source for CYP2A7 Gene

Gene Ontology (GO) - Biological Process for CYP2A7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019373 epoxygenase P450 pathway IBA --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with CYP2A7: view

No data available for SIGNOR curated interactions for CYP2A7 Gene

Drugs & Compounds for CYP2A7 Gene

(20) Drugs for CYP2A7 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Citalopram Approved Pharma 512
Codeine Approved, Illicit Pharma Full agonist, Agonist 77
Estradiol Approved, Investigational, Vet_approved Pharma Sex hormone 1318
Estrone Approved Pharma Agonist Estrogenic hormone 21
Formaldehyde Approved, Vet_approved Pharma 93

(23) Additional Compounds for CYP2A7 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
11,12,15-THETA
  • 11,12,15-TriHETRE
  • 11,12,15-Trihydroxyicosatrienoate
  • 11,12,15-Trihydroxyicosatrienoic acid
  • 11,12,15S-Trihydroxy-5Z,8Z,13E-eicosatrienoate
  • 11,12,15S-Trihydroxy-5Z,8Z,13E-eicosatrienoic acid
11,12-Epoxyeicosatrienoic acid
  • (5Z,8Z,14Z)-11,12-Epoxyeicosa-5,8,14-trienoate
  • (5Z,8Z,14Z)-11,12-Epoxyeicosa-5,8,14-trienoic acid
  • (5Z,8Z,14Z)-11,12-Epoxyicosa-5,8,14-trienoate
  • (5Z,8Z,14Z)-11,12-Epoxyicosa-5,8,14-trienoic acid
  • 10-(3-(2-Octenyl)oxiranyl)-5,8-Decadienoate
81276-02-0
11,14,15-THETA
  • (5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoic acid
  • (5Z,8Z,12E)-11,14,15-Trihydroxyicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-11,14,15-Trihydroxyicosa-5,8,12-trienoic acid
  • 11,14,15-Trihydroxy-5Z,8Z,12E-eicosatrienoate
11H-14,15-EETA
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyeicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyeicosa-5,8,12-trienoic acid
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyicosa-5,8,12-trienoate
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyicosa-5,8,12-trienoic acid
  • 11-Hydroxy-14,15-EETA
219535-29-2
12,13-EpOME
  • (+/-)-12(13)-epoxy-9Z-octadecenoate
  • (+/-)-12(13)-epoxy-9Z-octadecenoic acid
  • (9Z)-11-(3-pentyloxiran-2-yl)undec-9-enoate
  • (9Z)-11-(3-pentyloxiran-2-yl)undec-9-enoic acid
  • (9Z)-12,13-epoxyoctadecenoate
genes like me logo Genes that share compounds with CYP2A7: view

Transcripts for CYP2A7 Gene

Unigene Clusters for CYP2A7 Gene

Cytochrome P450, family 2, subfamily A, polypeptide 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CYP2A7 Gene

No ASD Table

Relevant External Links for CYP2A7 Gene

GeneLoc Exon Structure for
CYP2A7
ECgene alternative splicing isoforms for
CYP2A7

Expression for CYP2A7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CYP2A7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CYP2A7 Gene

This gene is overexpressed in Liver (x50.6).

NURSA nuclear receptor signaling pathways regulating expression of CYP2A7 Gene:

CYP2A7

SOURCE GeneReport for Unigene cluster for CYP2A7 Gene:

Hs.719890

Evidence on tissue expression from TISSUES for CYP2A7 Gene

  • Liver(5)
genes like me logo Genes that share expression patterns with CYP2A7: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CYP2A7 Gene

Orthologs for CYP2A7 Gene

This gene was present in the common ancestor of animals.

Orthologs for CYP2A7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CYP2A7 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 35
  • 87 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Cyp2a5 34 16 35
  • 84.55 (n)
Cyp2a4 35
  • 82 (a)
ManyToMany
Cyp2a12 35
  • 71 (a)
ManyToMany
Cyp2a22 35
  • 71 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia CYP2A13 35 35
  • 84 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Cyp2a3 34
  • 83.99 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 58 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 59 (a)
ManyToMany
-- 35
  • 58 (a)
ManyToMany
-- 35
  • 58 (a)
ManyToMany
-- 35
  • 58 (a)
ManyToMany
-- 35
  • 57 (a)
ManyToMany
-- 35
  • 56 (a)
ManyToMany
-- 35
  • 56 (a)
ManyToMany
-- 35
  • 55 (a)
ManyToMany
-- 35
  • 54 (a)
ManyToMany
-- 35
  • 54 (a)
ManyToMany
-- 35
  • 54 (a)
ManyToMany
-- 35
  • 53 (a)
ManyToMany
-- 35
  • 53 (a)
ManyToMany
-- 35
  • 52 (a)
ManyToMany
-- 35
  • 46 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC548374 34
  • 58.59 (n)
worm
(Caenorhabditis elegans)
Secernentea cyp-36A1 34
  • 43.65 (n)
K09A11.3 36
  • 34 (a)
C34B7.3 36
  • 33 (a)
C50H11.15 36
  • 33 (a)
K05D4.4 36
  • 33 (a)
K09A11.4 36
  • 33 (a)
F42A9.5 36
  • 32 (a)
K09A11.2 36
  • 32 (a)
B0213.15 36
  • 31 (a)
C49C8.4 36
  • 31 (a)
F41B5.2 36
  • 31 (a)
F41B5.3 36
  • 31 (a)
R08F11.3 36
  • 31 (a)
T10H4.10 36
  • 31 (a)
B0213.11 36
  • 30 (a)
B0213.12 36
  • 30 (a)
B0213.14 36
  • 30 (a)
B0213.16 36
  • 30 (a)
B0304.3 36
  • 30 (a)
C03G6.15 36
  • 30 (a)
C45H4.17 36
  • 30 (a)
K07C6.5 36
  • 30 (a)
T10H4.11 36
  • 30 (a)
C45H4.2 36
  • 29 (a)
F14H3.10 36
  • 29 (a)
K07C6.2 36
  • 29 (a)
K07C6.3 36
  • 29 (a)
B0213.10 36
  • 28 (a)
C03G6.14 36
  • 28 (a)
C49G7.8 36
  • 28 (a)
F41B5.7 36
  • 28 (a)
K09D9.2 36
  • 28 (a)
Y5H2B.6 36
  • 28 (a)
C41G6.1 36
  • 27 (a)
C25E10.2 36
  • 26 (a)
K07C6.4 36
  • 26 (a)
T09H2.1 36
  • 26 (a)
Species where no ortholog for CYP2A7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for CYP2A7 Gene

ENSEMBL:
Gene Tree for CYP2A7 (if available)
TreeFam:
Gene Tree for CYP2A7 (if available)

Paralogs for CYP2A7 Gene

Variants for CYP2A7 Gene

Sequence variations from dbSNP and Humsavar for CYP2A7 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000138835 -- 40,883,895(+) GCGGG(G/T)TCTGA nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000867797 -- 40,884,862(+) CCTTT(G/T)CTGGG nc-transcript-variant, utr-variant-5-prime
rs1001369988 -- 40,887,686(+) TTTTT(A/C)GTAGG upstream-variant-2KB
rs1002234360 -- 40,881,027(+) TATGG(A/C/G)GAGAT intron-variant
rs1002324960 -- 40,885,585(+) TGTGT(A/G)TGTGT nc-transcript-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for CYP2A7 Gene

Variant ID Type Subtype PubMed ID
dgv1046e212 CNV gain 25503493
dgv1047e212 CNV loss 25503493
dgv1049e212 CNV loss 25503493
dgv1051e212 CNV gain 25503493
dgv142n111 CNV deletion 26073780
dgv3539n100 CNV loss 25217958
dgv3540n100 CNV gain 25217958
dgv522e201 CNV deletion 23290073
dgv643e199 CNV deletion 23128226
dgv6442n54 CNV loss 21841781
dgv6446n54 CNV loss 21841781
dgv6448n54 CNV gain+loss 21841781
dgv6449n54 CNV gain 21841781
dgv6450n54 CNV loss 21841781
dgv6451n54 CNV gain+loss 21841781
dgv6452n54 CNV gain 21841781
esv1001236 CNV deletion 20482838
esv1005181 CNV gain 20482838
esv21610 CNV gain+loss 19812545
esv2718568 CNV deletion 23290073
esv2718569 CNV deletion 23290073
esv2718570 CNV deletion 23290073
esv2758762 CNV gain+loss 17122850
esv2760509 CNV gain+loss 21179565
esv33053 CNV gain 17666407
esv3556401 CNV deletion 23714750
esv3644361 CNV loss 21293372
esv3893202 CNV gain+loss 25118596
nsv1056244 CNV gain 25217958
nsv1065886 CNV loss 25217958
nsv1066637 CNV gain 25217958
nsv1125310 OTHER inversion 24896259
nsv1160625 CNV deletion 26073780
nsv435697 CNV deletion 17901297
nsv511622 CNV loss 21212237
nsv579545 CNV gain 21841781
nsv579590 CNV loss 21841781
nsv963050 CNV duplication 23825009
nsv9729 CNV loss 18304495
nsv978816 CNV duplication 23825009

Variation tolerance for CYP2A7 Gene

Residual Variation Intolerance Score: 99.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.84; 91.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CYP2A7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CYP2A7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYP2A7 Gene

Disorders for CYP2A7 Gene

Relevant External Links for CYP2A7

Genetic Association Database (GAD)
CYP2A7
Human Genome Epidemiology (HuGE) Navigator
CYP2A7
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CYP2A7

No disorders were found for CYP2A7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CYP2A7 Gene

Publications for CYP2A7 Gene

  1. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. (PMID: 7668294) Fernandez-Salguero P. … Idle J.R. (Am. J. Hum. Genet. 1995) 2 3 4 22 64
  2. Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity. (PMID: 12325023) Oscarson M. … Ingelman-Sundberg M. (Hum. Mutat. 2002) 3 22 46 64
  3. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PMID: 15128046) Nelson D.R. … Nebert D.W. (Pharmacogenetics 2004) 2 3 64
  4. Expression of CYP2A genes in human liver and extrahepatic tissues. (PMID: 10353262) Koskela S. … Raunio H. (Biochem. Pharmacol. 1999) 3 22 64
  5. Expression and alternative splicing of the cytochrome P-450 CYP2A7. (PMID: 7864805) Ding S. … Wolf C.R. (Biochem. J. 1995) 3 22 64

Products for CYP2A7 Gene

Sources for CYP2A7 Gene

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