Aliases for SLC36A2 Gene
External Ids for SLC36A2 Gene
This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria. [provided by RefSeq, Sep 2010]
GeneCards Summary for SLC36A2 Gene
SLC36A2 (Solute Carrier Family 36 (Proton/Amino Acid Symporter), Member 2) is a Protein Coding gene. Diseases associated with SLC36A2 include hyperglycinuria and iminoglycinuria, digenic. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include L-alanine transmembrane transporter activity and L-proline transmembrane transporter activity. An important paralog of this gene is SLC36A1.
UniProtKB/Swiss-Prot for SLC36A2 Gene
Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity).