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Aliases for SAMD13 Gene

Aliases for SAMD13 Gene

  • Sterile Alpha Motif Domain Containing 13 2 3 5
  • SAM Domain-Containing Protein 13 3 4
  • Sterile Alpha Motif Domain-Containing Protein 13 3
  • Dnaj-Like Protein (LOC148418) 3
  • HSD-41 3
  • HSD-42 3

External Ids for SAMD13 Gene

Previous GeneCards Identifiers for SAMD13 Gene

  • GC01P084477
  • GC01P084536
  • GC01P084764
  • GC01P082874
  • GC01P084298

Summaries for SAMD13 Gene

GeneCards Summary for SAMD13 Gene

SAMD13 (Sterile Alpha Motif Domain Containing 13) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is SAMD1.

Additional gene information for SAMD13 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAMD13 Gene

Genomics for SAMD13 Gene

Regulatory Elements for SAMD13 Gene

Enhancers for SAMD13 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H084155 1.2 Ensembl ENCODE dbSUPER 11.1 -118.4 -118419 1 JUN FEZF1 BATF ZIC2 ZNF121 POLR2A FOS NFE2 NFE2L2 ZNF571 SAMD13 GC01P084086 LOC100128775
GH01H084142 0.9 ENCODE dbSUPER 12.5 -129.2 -129225 6 JUN MAX JUNB REST YY1 JUND ZNF316 POLR2A FOS MYC SAMD13 RPF1 PRKACB GC01P084086 LOC100128775
GH01H084432 1 Ensembl ENCODE 10.8 +159.6 159575 3 CTCF PKNOX1 ZNF384 RAD21 RFX5 CC2D1A POLR2A SCRT2 SMC3 ZNF143 DNASE2B SPATA1 GNG5 UOX SAMD13 RPF1 ENSG00000199959 GC01M084333
GH01H084298 1.3 ENCODE dbSUPER 6.2 +26.1 26124 6 HDGF ARNT SIN3A FEZF1 ZNF2 YY1 ZNF143 SP3 REST GLIS1 ENSG00000271576 BCL10 DNASE2B UOX RPF1 SAMD13 ENSG00000199959 ENSG00000249237
GH01H084405 0.7 ENCODE 10.5 +132.0 132002 3 FOXA2 NFIB MAX RAD21 YY1 FOSL1 GATA3 POLR2A FOS NFE2 SAMD13 DNASE2B ENSG00000199959 GC01M084333
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SAMD13 on UCSC Golden Path with GeneCards custom track

Genomic Location for SAMD13 Gene

Chromosome:
1
Start:
84,274,952 bp from pter
End:
84,389,957 bp from pter
Size:
115,006 bases
Orientation:
Plus strand

Genomic View for SAMD13 Gene

Genes around SAMD13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SAMD13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SAMD13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAMD13 Gene

Proteins for SAMD13 Gene

  • Protein details for SAMD13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VXD3-SAM13_HUMAN
    Recommended name:
    Sterile alpha motif domain-containing protein 13
    Protein Accession:
    Q5VXD3
    Secondary Accessions:
    • B3KPW8
    • D3DT11
    • Q53AI4
    • Q5VXD2
    • Q5VXD4

    Protein attributes for SAMD13 Gene

    Size:
    122 amino acids
    Molecular mass:
    13570 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SAMD13 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SAMD13 Gene

Post-translational modifications for SAMD13 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SAMD13 Gene

Domains & Families for SAMD13 Gene

Gene Families for SAMD13 Gene

Protein Domains for SAMD13 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SAMD13 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SAMD13: view

No data available for UniProtKB/Swiss-Prot for SAMD13 Gene

Function for SAMD13 Gene

Phenotypes From GWAS Catalog for SAMD13 Gene

Phenotypes for SAMD13 Gene

genes like me logo Genes that share phenotypes with SAMD13: view

Animal Model Products

CRISPR Products

miRNA for SAMD13 Gene

miRTarBase miRNAs that target SAMD13

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SAMD13 Gene

Localization for SAMD13 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SAMD13 gene
Compartment Confidence
cytosol 2
extracellular 1
nucleus 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAMD13 Gene

Pathways & Interactions for SAMD13 Gene

SuperPathways for SAMD13 Gene

No Data Available

Interacting Proteins for SAMD13 Gene

Gene Ontology (GO) - Biological Process for SAMD13 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SAMD13 Gene

Drugs & Compounds for SAMD13 Gene

No Compound Related Data Available

Transcripts for SAMD13 Gene

Unigene Clusters for SAMD13 Gene

Sterile alpha motif domain containing 13:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for SAMD13 Gene

No ASD Table

Relevant External Links for SAMD13 Gene

GeneLoc Exon Structure for
SAMD13
ECgene alternative splicing isoforms for
SAMD13

Expression for SAMD13 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SAMD13 Gene

mRNA differential expression in normal tissues according to GTEx for SAMD13 Gene

This gene is overexpressed in Colon - Transverse (x6.2) and Testis (x5.9).

Protein differential expression in normal tissues from HIPED for SAMD13 Gene

This gene is overexpressed in Skin (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SAMD13 Gene



Protein tissue co-expression partners for SAMD13 Gene

NURSA nuclear receptor signaling pathways regulating expression of SAMD13 Gene:

SAMD13

SOURCE GeneReport for Unigene cluster for SAMD13 Gene:

Hs.591445
genes like me logo Genes that share expression patterns with SAMD13: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SAMD13 Gene

Orthologs for SAMD13 Gene

This gene was present in the common ancestor of animals.

Orthologs for SAMD13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SAMD13 33 34
  • 99.71 (n)
cow
(Bos Taurus)
Mammalia SAMD13 34
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Samd13 34
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SAMD13 34
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SAMD13 34
  • 23 (a)
OneToOne
chicken
(Gallus gallus)
Aves SAMD13 34
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SAMD13 34
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia samd13 33
  • 77.24 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.32470 33
zebrafish
(Danio rerio)
Actinopterygii samd13 33 34
  • 73.54 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG2662 34
  • 9 (a)
OneToMany
Species where no ortholog for SAMD13 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SAMD13 Gene

ENSEMBL:
Gene Tree for SAMD13 (if available)
TreeFam:
Gene Tree for SAMD13 (if available)

Paralogs for SAMD13 Gene

Paralogs for SAMD13 Gene

(13) SIMAP similar genes for SAMD13 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with SAMD13: view

Variants for SAMD13 Gene

Sequence variations from dbSNP and Humsavar for SAMD13 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000053283 -- 84,343,249(+) ACACT(A/G)TTGGT intron-variant
rs1000079386 -- 84,298,834(+) GGACG(A/G)GGTGG intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000103767 -- 84,343,013(+) AAGAA(A/G)AAAAC intron-variant
rs1000181497 -- 84,297,521(+) TAGCC(A/T)GTTTG intron-variant, upstream-variant-2KB
rs1000196268 -- 84,316,843(+) CCATG(A/G)ACTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SAMD13 Gene

Variant ID Type Subtype PubMed ID
nsv1744 CNV insertion 18451855
nsv830414 CNV gain 17160897
nsv830426 CNV gain 17160897

Variation tolerance for SAMD13 Gene

Residual Variation Intolerance Score: 48% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.10; 2.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SAMD13 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SAMD13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SAMD13 Gene

Disorders for SAMD13 Gene

Relevant External Links for SAMD13

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SAMD13

No disorders were found for SAMD13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAMD13 Gene

Publications for SAMD13 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for SAMD13 Gene

Sources for SAMD13 Gene

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