Aliases for CSTF2 Gene
External Ids for CSTF2 Gene
Previous GeneCards Identifiers for CSTF2 Gene
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008]
GeneCards Summary for CSTF2 Gene
CSTF2 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa) is a Protein Coding gene. Diseases associated with CSTF2 include cytomegalovirus infection. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Gene Expression. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RBMX2.
UniProtKB/Swiss-Prot for CSTF2 Gene
One of the multiple factors required for polyadenylation and 3-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity).