Aliases for CSF3R Gene
External Ids for CSF3R Gene
Previous Symbols for CSF3R Gene
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
GeneCards Summary for CSF3R Gene
CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte)) is a Protein Coding gene. Diseases associated with CSF3R include chronic neutrophilic leukemia and neutrophilia, hereditary. Among its related pathways are PI3K-Akt signaling pathway and Pathways in cancer. GO annotations related to this gene include receptor activity and cytokine receptor activity. An important paralog of this gene is IL12RB2.
UniProtKB/Swiss-Prot for CSF3R Gene
Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.