Aliases for CNGA2 Gene
External Ids for CNGA2 Gene
Previous Symbols for CNGA2 Gene
The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. [provided by RefSeq, Jan 2010]
GeneCards Summary for CNGA2 Gene
CNGA2 (Cyclic Nucleotide Gated Channel Alpha 2) is a Protein Coding gene. Diseases associated with CNGA2 include neuroblastoma. GO annotations related to this gene include calmodulin binding and cAMP binding. An important paralog of this gene is KCNH1.
UniProtKB/Swiss-Prot for CNGA2 Gene
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons