Aliases for PLIN2 Gene
External Ids for PLIN2 Gene
Previous HGNC Symbols for PLIN2 Gene
Previous GeneCards Identifiers for PLIN2 Gene
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
GeneCards Summary for PLIN2 Gene
PLIN2 (Perilipin 2) is a Protein Coding gene. Diseases associated with PLIN2 include enteropathica and very long-chain acyl-coenzyme a dehydrogenase deficiency. Among its related pathways are Metabolism and HIF-1-alpha transcription factor network. An important paralog of this gene is PLIN3.
UniProtKB/Swiss-Prot for PLIN2 Gene
May be involved in development and maintenance of adipose tissue.