Aliases for CLTC Gene
External Ids for CLTC Gene
Previous Symbols for CLTC Gene
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008]
GeneCards Summary for CLTC Gene
CLTC (Clathrin, Heavy Chain (Hc)) is a Protein Coding gene. Diseases associated with CLTC include inflammatory myofibroblastic tumor and ophthalmia neonatorum. Among its related pathways are Signaling by GPCR and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include structural molecule activity.
UniProtKB/Swiss-Prot for CLTC Gene
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network