Aliases for TAGAP Gene
External Ids for TAGAP Gene
Previous GeneCards Identifiers for TAGAP Gene
This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
GeneCards Summary for TAGAP Gene
TAGAP (T-Cell Activation RhoGTPase Activating Protein) is a Protein Coding gene. Diseases associated with TAGAP include Diabetes Mellitus, Insulin-Dependent, 21 and Auditory Agnosia. Among its related pathways are p75 NTR receptor-mediated signalling and Signaling by Rho GTPases. GO annotations related to this gene include guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGAP20.
UniProtKB/Swiss-Prot for TAGAP Gene
May function as a GTPase-activating protein and may play important roles during T-cell activation.