Aliases for FCRL3 Gene
External Ids for FCRL3 Gene
Previous GeneCards Identifiers for FCRL3 Gene
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for FCRL3 Gene
FCRL3 (Fc Receptor Like 3) is a Protein Coding gene. Diseases associated with FCRL3 include Neuromyelitis Optica and Rheumatoid Arthritis. Among its related pathways are B Cell Development Pathways. An important paralog of this gene is FCRL5.