Aliases for GALNT13 Gene
- Polypeptide N-Acetylgalactosaminyltransferase 13 2 3 5
- Polypeptide GalNAc Transferase 13 2 3 4
- UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 13 (GalNAc-T13) 2 3
- UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 13 3 4
- Protein-UDP Acetylgalactosaminyltransferase 13 3 4
- Pp-GaNTase 13 3 4
External Ids for GALNT13 Gene
Previous GeneCards Identifiers for GALNT13 Gene
The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 220.127.116.11) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM, Apr 2004]
GeneCards Summary for GALNT13 Gene
GALNT13 (Polypeptide N-Acetylgalactosaminyltransferase 13) is a Protein Coding gene. Among its related pathways are Metabolism and Mucin type O-Glycan biosynthesis. GO annotations related to this gene include carbohydrate binding and polypeptide N-acetylgalactosaminyltransferase activity. An important paralog of this gene is GALNT4.
UniProtKB/Swiss-Prot for GALNT13 Gene
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a much stronger activity than GALNT1 to transfer GalNAc to mucin peptides, such as Muc5Ac and Muc7. Able to glycosylate SDC3. May be responsible for the synthesis of Tn antigen in neuronal cells.