Aliases for CHRNB4 Gene
External Ids for CHRNB4 Gene
Previous GeneCards Identifiers for CHRNB4 Gene
GeneCards Summary for CHRNB4 Gene
CHRNB4 (Cholinergic Receptor Nicotinic Beta 4 Subunit) is a Protein Coding gene. Diseases associated with CHRNB4 include Substance Dependence and Nicotine Dependence, Protection Against. Among its related pathways are Innate Immune System and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. GO annotations related to this gene include extracellular ligand-gated ion channel activity and ligand-gated ion channel activity. An important paralog of this gene is CHRNB2.
UniProtKB/Swiss-Prot for CHRNB4 Gene
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.