Aliases for TMC6 Gene
External Ids for TMC6 Gene
Previous HGNC Symbols for TMC6 Gene
Previous GeneCards Identifiers for TMC6 Gene
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq, Jul 2008]
GeneCards Summary for TMC6 Gene
UniProtKB/Swiss-Prot for TMC6 Gene
Probable ion channel.