Aliases for PADI2 Gene
Aliases for PADI2 Gene
External Ids for PADI2 Gene
- HGNC: 18341
- Entrez Gene: 11240
- Ensembl: ENSG00000117115
- OMIM: 607935
- UniProtKB: Q9Y2J8
Previous GeneCards Identifiers for PADI2 Gene
- GC01M017130
- GC01M016434
- GC01M016775
- GC01M016776
- GC01M017138
- GC01M017265
- GC01M017393
- GC01M015637
Summaries for PADI2 Gene
-
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
GeneCards Summary for PADI2 Gene
PADI2 (Peptidyl Arginine Deiminase 2) is a Protein Coding gene. Diseases associated with PADI2 include Alzheimer Disease 16 and Alzheimer Disease. Among its related pathways are Innate Immune System and Chromatin organization. GO annotations related to this gene include calcium ion binding and protein-arginine deiminase activity. An important paralog of this gene is PADI1.
UniProtKB/Swiss-Prot for PADI2 Gene
-
Catalyzes the deimination of arginine residues of proteins.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PADI2 Gene
Genomics for PADI2 Gene
Regulatory Elements for PADI2 Gene
Enhancers for PADI2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G017096 | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 104.9 | +20.8 | 20848 | 3.4 | PKNOX1 KLF1 FOXA2 KLF17 ZMYM3 EBF1 ZIC2 ZNF121 POLR2A SCRT2 | PADI2 PADI4 CROCCP2 SDHB |
| GH01G017102 | 0.7 | dbSUPER | 90.5 | +17.1 | 17101 | 3.3 | BCOR NFIB ZMYM3 SIN3A MNT TBX21 ZKSCAN1 NFIC CBX1 HDAC2 | PADI2 SDHB |
| GH01G017103 | 0.7 | dbSUPER | 90.5 | +17.1 | 17081 | 2.8 | BCOR NFIB ZMYM3 SIN3A MNT ZKSCAN1 NFIC CBX1 HDAC2 POLR2A | PADI2 SDHB |
| GH01G017104 | 0.7 | dbSUPER | 90.5 | +17.1 | 17052 | 3.0 | BCOR NFIB ZMYM3 SIN3A MNT ZKSCAN1 NFIC CBX1 HDAC2 POLR2A | PADI2 SDHB |
| GH01G017100 | 0.7 | dbSUPER | 90.5 | +17.1 | 17097 | 3.2 | BCOR NFIB ZMYM3 SIN3A MNT ZKSCAN1 NFIC CBX1 HDAC2 POLR2A | PADI2 SDHB |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around PADI2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for PADI2 Gene
- Chromosome:
- 1
- Start:
- 17,066,761 bp from pter
- End:
- 17,119,453 bp from pter
- Size:
- 52,693 bases
- Orientation:
- Minus strand
Genomic View for PADI2 Gene
Genes around PADI2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.13 by Ensembl
- 1p36.13 by Entrez Gene
- 1p36.13 by HGNC
PADI2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PADI2 Gene
Proteins for PADI2 Gene
-
Protein details for PADI2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y2J8-PADI2_HUMAN
- Recommended name:
- Protein-arginine deiminase type-2
- Protein Accession:
- Q9Y2J8
- Q96DA7
- Q9UPN2
Protein attributes for PADI2 Gene
- Size:
- 665 amino acids
- Molecular mass:
- 75564 Da
- Cofactor:
- Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA76838.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for PADI2 Gene
Protein Expression for PADI2 Gene
Selected DME Specific Peptides for PADI2 Gene
- Q9Y2J8:
-
- AQQVQAPV
- VSPPVTV
- HCGTNVRRKPF
- APWIMTP
- LGIPKPFGP
Post-translational modifications for PADI2 Gene
Other Protein References for PADI2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
Abcam proteins for PADI2
Domains & Families for PADI2 Gene
Gene Families for PADI2 Gene
Protein Domains for PADI2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PADI2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y2J8- Family:
-
- Belongs to the protein arginine deiminase family.
Function for PADI2 Gene
Molecular function for PADI2 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Protein L-arginine + H(2)O = protein L-citrulline + NH(3).
- UniProtKB/Swiss-Prot Function:
- Catalyzes the deimination of arginine residues of proteins.
Enzyme Numbers (IUBMB) for PADI2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004668 | protein-arginine deiminase activity | IDA | 12392711 |
| GO:0005509 | calcium ion binding | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
| GO:0030331 | estrogen receptor binding | IPI | 22853951 |
Phenotypes for PADI2 Gene
- MGI mutant phenotypes for PADI2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for PADI2:
Animal Model Products
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miRNA for PADI2 Gene
- miRTarBase miRNAs that target PADI2
-
- hsa-mir-3678-3p (MIRT498280)
- hsa-mir-2467-3p (MIRT498281)
- hsa-mir-3158-5p (MIRT498282)
- hsa-mir-509-5p (MIRT498283)
- hsa-mir-509-3-5p (MIRT498284)
- hsa-mir-4418 (MIRT498285)
- hsa-mir-4643 (MIRT625829)
- hsa-mir-8485 (MIRT625830)
- hsa-mir-5006-3p (MIRT655537)
- hsa-mir-629-3p (MIRT655538)
- hsa-mir-4755-5p (MIRT655539)
- hsa-mir-6867-3p (MIRT655540)
- hsa-mir-4713-5p (MIRT655541)
- hsa-mir-211-5p (MIRT655542)
- hsa-mir-204-5p (MIRT655543)
- hsa-mir-623 (MIRT655544)
- hsa-mir-6826-3p (MIRT655545)
- hsa-mir-3128 (MIRT655546)
- hsa-mir-3667-3p (MIRT655547)
- hsa-mir-6734-3p (MIRT655548)
- hsa-mir-5088-3p (MIRT655549)
- hsa-mir-6795-3p (MIRT655550)
- hsa-mir-6887-3p (MIRT655551)
miRNA Products
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- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PADI2 Gene
Localization for PADI2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PADI2 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 5 |
| nucleus | 4 |
| lysosome | 4 |
| mitochondrion | 3 |
| cytoskeleton | 2 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005634 | nucleus | IBA | -- |
| GO:0005737 | cytoplasm | IDA | 12392711 |
| GO:0005829 | cytosol | TAS | -- |
| GO:0035327 | transcriptionally active chromatin | IDA | 22853951 |
Pathways & Interactions for PADI2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Chromatin organization | ||
Pathways by source for PADI2 Gene
5 Reactome pathways for PADI2 Gene
Interacting Proteins for PADI2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006325 | chromatin organization | TAS | -- |
| GO:0010848 | regulation of chromatin disassembly | IDA | 22853951 |
| GO:0018101 | protein citrullination | IDA | 12392711 |
| GO:0021762 | substantia nigra development | IEP | 22926577 |
| GO:0030520 | intracellular estrogen receptor signaling pathway | IMP | 22853951 |
No data available for SIGNOR curated interactions for PADI2 Gene
Drugs & Compounds for PADI2 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Ammonia |
|
7664-41-7 |
|
Transcripts for PADI2 Gene
mRNA/cDNA for PADI2 Gene
- (2) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (78) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PADI2 Gene
CRISPR Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP5: |
Expression for PADI2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Monocytes Peripheral Blood
-
Eye (Sensory Organs)
- Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Epithelial Cells
- Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Brain (Nervous System)
- Oligodendrocyte Precursor Cells Forebrain White Matter
-
Colon (Gastrointestinal Tract)
-
Spinal Cord (Nervous System)
-
Skeletal Muscle (Muscoskeletal System)
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for PADI2 Gene
This gene is overexpressed in Muscle - Skeletal (x11.1), Whole Blood (x9.1), and Brain - Spinal cord (cervical c-1) (x7.6).
This gene is overexpressed in Spinal cord (35.2), Retina (6.5), and Frontal cortex (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PADI2 Gene
NURSA nuclear receptor signaling pathways regulating expression of PADI2 Gene:
PADI2SOURCE GeneReport for Unigene cluster for PADI2 Gene:
Hs.33455Evidence on tissue expression from TISSUES for PADI2 Gene
- Nervous system(4.7)
- Skin(4.2)
- Pancreas(4.1)
- Muscle(3.1)
- Blood(2.3)
- Eye(2.1)
Primer Products
-
OriGene qPCR primer pairs for PADI2
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PADI2 Gene
Orthologs for PADI2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PADI2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | PADI2 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | PADI2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Padi2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Padi2 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PADI2 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | PADI2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | PADI2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | PADI2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | padi2 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | padi2-prov 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | padi2 34 35 |
|
||
| sbcb968 34 |
|
- Species where no ortholog for PADI2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for PADI2 Gene
Variants for PADI2 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000042855 | -- | 17,097,534(+) | TCACT(A/G)CTGAG | intron-variant | |
| rs1000146890 | -- | 17,086,644(+) | ACCAC(A/G)TGGTA | nc-transcript-variant, reference, synonymous-codon | |
| rs1000192763 | -- | 17,081,891(+) | GTGGA(A/T)CATCT | intron-variant | |
| rs1000293448 | -- | 17,109,006(+) | GGTGA(C/G)AGGAT | intron-variant | |
| rs1000321427 | -- | 17,104,231(+) | CTTGC(A/G)GTGAG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2422314 | CNV | duplication | 17116639 |
| esv2758925 | CNV | gain+loss | 17122850 |
| esv3305460 | CNV | mobile element insertion | 20981092 |
| esv3310333 | CNV | mobile element insertion | 20981092 |
| esv3585359 | CNV | gain | 21293372 |
| nsv1009931 | CNV | gain | 25217958 |
| nsv1076191 | CNV | deletion | 25765185 |
| nsv1133818 | CNV | deletion | 24896259 |
| nsv1137735 | CNV | deletion | 24896259 |
| nsv1145323 | CNV | deletion | 24896259 |
| nsv428421 | CNV | gain+loss | 18775914 |
| nsv460662 | CNV | loss | 19166990 |
| nsv545690 | CNV | gain | 21841781 |
| nsv545691 | CNV | loss | 21841781 |
| nsv834280 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
80.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.05;
50.47% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for PADI2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PADI2 Gene
Disorders for PADI2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| alzheimer disease 16 |
|
|
| alzheimer disease |
|
|
Search PADI2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for PADI2
No data available for UniProtKB/Swiss-Prot and Genatlas for PADI2 Gene
Publications for PADI2 Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- A two-stage case-control association study of PADI2 with schizophrenia. (PMID: 19478818) Watanabe Y. … Someya T. (J. Hum. Genet. 2009) 3 46 64
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
- Comparison of enzymatic properties between hPADI2 and hPADI4. (PMID: 15629448) Nakayama-Hamada M. … Yamamoto K. (Biochem. Biophys. Res. Commun. 2005) 3 22 64
- Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors. (PMID: 15854045) Dong S. … Takahara H. (J. Invest. Dermatol. 2005) 22 25 64
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- GeneTex PADI2 antibody for PADI2
- Search GeneTex for Proteins for PADI2
- ViGene Biosciences adenoviral particle packaged cDNA for PADI2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PADI2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PADI2 gene
- Search ViGene Biosciences for PADI2
- Santa Cruz Biotechnology (SCBT) Antibodies for PADI2
- Search Santa Cruz Biotechnology (SCBT) for PADI2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PADI2
- Horizon Cell Lines for PADI2
- Cyagen custom Knockout/knockin (KOKI) mouse models for PADI2
- VectorBuilder custom plasmid, inducible vectors for PADI2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PADI2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for PADI2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer