Aliases for SOX21 Gene
External Ids for SOX21 Gene
Previous GeneCards Identifiers for SOX21 Gene
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]
GeneCards Summary for SOX21 Gene
SOX21 (SRY-Box 21) is a Protein Coding gene. Among its related pathways are Mesodermal Commitment Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is SOX14.
UniProtKB/Swiss-Prot for SOX21 Gene
May play a role as an activator of transcription of OPRM1.