Aliases for SOX21 Gene
External Ids for SOX21 Gene
Previous GeneCards Identifiers for SOX21 Gene
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]
GeneCards Summary for SOX21 Gene
SOX21 (SRY (Sex Determining Region Y)-Box 21) is a Protein Coding gene. Among its related pathways are ERK Signaling. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is SOX3.
UniProtKB/Swiss-Prot for SOX21 Gene
May play a role as an activator of transcription of OPRM1.