Aliases for KAT7 Gene
External Ids for KAT7 Gene
Previous HGNC Symbols for KAT7 Gene
Previous GeneCards Identifiers for KAT7 Gene
GeneCards Summary for KAT7 Gene
KAT7 (K(Lysine) Acetyltransferase 7) is a Protein Coding gene. Among its related pathways are RNA Polymerase I Promoter Opening and RNA Polymerase I Promoter Opening. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and histone acetyltransferase activity. An important paralog of this gene is KAT8.
UniProtKB/Swiss-Prot for KAT7 Gene
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.