Aliases for RAPGEF4 Gene
External Ids for RAPGEF4 Gene
Previous GeneCards Identifiers for RAPGEF4 Gene
GeneCards Summary for RAPGEF4 Gene
RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4) is a Protein Coding gene. Diseases associated with RAPGEF4 include hypoglycemic coma. Among its related pathways are Immune System and Signaling by GPCR. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras GTPase binding. An important paralog of this gene is RASGEF1B.
UniProtKB/Swiss-Prot for RAPGEF4 Gene
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).