Aliases for KIF2C Gene
External Ids for KIF2C Gene
Previous HGNC Symbols for KIF2C Gene
Previous GeneCards Identifiers for KIF2C Gene
This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for KIF2C Gene
KIF2C (Kinesin Family Member 2C) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Cell Cycle, Mitotic. GO annotations related to this gene include microtubule motor activity and centromeric DNA binding. An important paralog of this gene is KIF2B.
UniProtKB/Swiss-Prot for KIF2C Gene
In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.