Aliases for MAGED2 Gene
External Ids for MAGED2 Gene
Previous GeneCards Identifiers for MAGED2 Gene
This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). This gene may also be involved in several types of cancer, including breast cancer and melanoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for MAGED2 Gene
MAGED2 (MAGE Family Member D2) is a Protein Coding gene. Diseases associated with MAGED2 include Bartter Disease Type 5 and Antenatal Bartter Syndrome. Among its related pathways are Response to elevated platelet cytosolic Ca2+. An important paralog of this gene is TRO.
UniProtKB/Swiss-Prot for MAGED2 Gene
Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule.