Aliases for NEU3 Gene
External Ids for NEU3 Gene
Previous GeneCards Identifiers for NEU3 Gene
This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008]
GeneCards Summary for NEU3 Gene
NEU3 (Neuraminidase 3 (Membrane Sialidase)) is a Protein Coding gene. Diseases associated with NEU3 include galactosialidosis and angiokeratoma. Among its related pathways are Other glycan degradation and Sphingolipid metabolism. GO annotations related to this gene include exo-alpha-(2->3)-sialidase activity and exo-alpha-(2->8)-sialidase activity. An important paralog of this gene is NEU4.
UniProtKB/Swiss-Prot for NEU3 Gene
Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates.