Aliases for PRDX4 Gene
Aliases for PRDX4 Gene
External Ids for PRDX4 Gene
- HGNC: 17169
- Entrez Gene: 10549
- Ensembl: ENSG00000123131
- OMIM: 300927
- UniProtKB: Q13162
Previous GeneCards Identifiers for PRDX4 Gene
- GC0XP022492
- GC0XP022256
- GC0XP022884
- GC0XP023047
- GC0XP023445
- GC0XP021425
Summaries for PRDX4 Gene
-
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]
GeneCards Summary for PRDX4 Gene
PRDX4 (Peroxiredoxin 4) is a Protein Coding gene. Diseases associated with PRDX4 include Scurvy. Among its related pathways are Selenium Pathway and Prostaglandin 2 biosynthesis and metabolism FM. GO annotations related to this gene include protein homodimerization activity and antioxidant activity. An important paralog of this gene is PRDX3.
UniProtKB/Swiss-Prot for PRDX4 Gene
-
Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRDX4 Gene
Genomics for PRDX4 Gene
Regulatory Elements for PRDX4 Gene
Enhancers for PRDX4 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around PRDX4 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the PRDX4 gene promoter:
Regulatory Element Products
Genomic Location for PRDX4 Gene
- Chromosome:
- X
- Start:
- 23,664,260 bp from pter
- End:
- 23,686,399 bp from pter
- Size:
- 22,140 bases
- Orientation:
- Plus strand
Genomic View for PRDX4 Gene
Genes around PRDX4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.11 by Ensembl
- Xp22.11 by Entrez Gene
- Xp22.11 by HGNC
PRDX4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PRDX4 Gene
Proteins for PRDX4 Gene
-
Protein details for PRDX4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q13162-PRDX4_HUMAN
- Recommended name:
- Peroxiredoxin-4
- Protein Accession:
- Q13162
- Q6FHT3
Protein attributes for PRDX4 Gene
- Size:
- 271 amino acids
- Molecular mass:
- 30540 Da
- Quaternary structure:
-
- Homodimer or heterodimer with PRDX1; disulfide-linked, upon oxidation.
- Miscellaneous:
-
- Irreversibly inactivated by overoxidation of Cys-124 (to Cys-SO(3)H) upon oxidative stress.
- The active site is the redox-active Cys-124 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-245-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.
Protein Expression for PRDX4 Gene
Selected DME Specific Peptides for PRDX4 Gene
Post-translational modifications for PRDX4 Gene
Other Protein References for PRDX4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for PRDX4
- R&D Systems Antibodies for PRDX4 (Peroxiredoxin 4)
- Novus Biologicals Antibodies for PRDX4
-
Cloud-Clone Corp. Antibodies for PRDX4
- Invitrogen Antibodies for PRDX4
- antibodies-online Antibodies for PRDX4: See all 104
- GeneTex PRDX4 antibody for PRDX4
-
Santa Cruz Biotechnology (SCBT) Antibodies for PRDX4
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for PRDX4
- Origene Custom Protein Services for PRDX4
- ProSpec Recombinant Proteins for PRDX4
-
Cloud-Clone Corp. Proteins for PRDX4
- antibodies-online Proteins for PRDX4: See all 27
- Search antibodies-online for peptides
- Search GeneTex for Proteins for PRDX4
Domains & Families for PRDX4 Gene
Gene Families for PRDX4 Gene
- HGNC:
Protein Domains for PRDX4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PRDX4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q13162- Domain:
-
- Contains 1 thioredoxin domain.
- Family:
-
- Belongs to the AhpC/TSA family.
Function for PRDX4 Gene
Molecular function for PRDX4 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- 2 R-SH + ROOH = R-S-S-R + H(2)O + ROH.
- UniProtKB/Swiss-Prot Function:
- Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
Enzyme Numbers (IUBMB) for PRDX4 Gene
- EC 1.11.1.15 63 4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016491 | oxidoreductase activity | IEA | -- |
Phenotypes for PRDX4 Gene
- MGI mutant phenotypes for PRDX4:
- inferred from 2 alleles
Animal Models for PRDX4 Gene
- MGI Knock Outs for PRDX4:
-
- Prdx4 tm1.1Jufu
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for PRDX4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PRDX4 gene
- Search ViGene Biosciences for PRDX4
CRISPR Products
-
OriGene CRISPR knockouts for PRDX4
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRDX4
- GenScript: Design CRISPR guide RNA sequences for PRDX4
miRNA for PRDX4 Gene
- miRTarBase miRNAs that target PRDX4
miRNA Products
- Search ViGene Biosciences for PRDX4
Clone Products
- OriGene clones in human for PRDX4
- OriGene ORF clones in human,mouse,rat for PRDX4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PRDX4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for PRDX4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PRDX4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PRDX4 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PRDX4 Gene
Localization for PRDX4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PRDX4 Gene
- Cytoplasm. Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| endoplasmic reticulum | 4 |
| mitochondrion | 3 |
| peroxisome | 1 |
| plasma membrane | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
Pathways & Interactions for PRDX4 Gene
More details on SuperPathways for PRDX4| Superpath | Contained pathways | |
|---|---|---|
| 1 | Prostaglandin 2 biosynthesis and metabolism FM | |
| 2 | Selenium Pathway |
Pathways by source for PRDX4 Gene
1 BioSystems pathway for PRDX4 Gene
1 GeneGo (Thomson Reuters) pathway for PRDX4 Gene
Interacting Proteins for PRDX4 Gene
Selected Interacting proteins:
Q13162-PRDX4_HUMAN
ENSP00000368646
for PRDX4 Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007252 | I-kappaB phosphorylation | TAS | 9388242 |
| GO:0019471 | 4-hydroxyproline metabolic process | IEA | -- |
| GO:0030198 | extracellular matrix organization | IEA | -- |
| GO:0045454 | cell redox homeostasis | IEA | -- |
| GO:0072593 | reactive oxygen species metabolic process | IEA | -- |
No data available for SIGNOR curated interactions for PRDX4 Gene
Drugs & Compounds for PRDX4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Docetaxel | Approved May 1996, Investigational | Pharma | Microtubulin disassembly inhibitor, Tubulin and VEGF inhibitor, Taxanes | 1859 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Water |
|
7732-18-5 |
|
Transcripts for PRDX4 Gene
mRNA/cDNA for PRDX4 Gene
- (2) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (356) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for PRDX4
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRDX4
- GenScript: Design CRISPR guide RNA sequences for PRDX4
miRNA Products
- Search ViGene Biosciences for PRDX4
Clone Products
- OriGene clones in human for PRDX4
- OriGene ORF clones in human,mouse,rat for PRDX4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PRDX4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||
| SP5: | - |
Expression for PRDX4 Gene
mRNA differential expression in normal tissues according to GTEx for PRDX4 Gene
This gene is overexpressed in Pancreas (x7.1) and Liver (x4.8).
This gene is overexpressed in Fetal testis (7.7) and Testis (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for PRDX4 Gene
SOURCE GeneReport for Unigene cluster for PRDX4 Gene Hs.83383
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for PRDX4
-
OriGene qPCR primer pairs and template standards for PRDX4
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for PRDX4 Gene
Orthologs for PRDX4 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | PRDX4 35 |
|
||
| PRDX4 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | PRDX4 35 |
|
||
| PRDX4 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Prdx4 35 |
|
||
| Prdx4 16 |
|
||||
| Prdx4 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Prdx4 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PRDX4 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | PRDX4 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | PRDX4 35 |
|
||
| PRDX4 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | PRDX4 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | prdx4 35 |
|
||
| Str.7399 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.14602 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | prdx4 35 |
|
||
| wufb59c09 35 |
|
||||
| prdx4 36 |
|
OneToOne | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.12199 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6888 37 |
|
|
|
| Jafrac1 37 |
|
|
|||
| Jafrac2 37 |
|
|
|||
| Prx5037 37 |
|
|
|||
| Jafrac2 35 |
|
||||
| Jafrac2 36 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | TPX3 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | R07E5.2 37 |
|
|
|
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | TSA1 36 |
|
ManyToMany | |
| TSA2 36 |
|
ManyToMany | |||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.10388 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToOne |
- Species with no ortholog for PRDX4:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for PRDX4 Gene
(3) SIMAP similar genes for PRDX4 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for PRDX4 Gene
Variants for PRDX4 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs747800675 | -- | 23,667,779(+) | GGTCG(C/G)CGACC | intron-variant, reference, missense | |
| rs747801205 | -- | 23,667,440(+) | GGGGG(A/G)GTAGG | intron-variant, upstream-variant-2KB | |
| rs747821709 | -- | 23,667,088(+) | TCACA(C/T)TGCAT | intron-variant, upstream-variant-2KB | |
| rs747837271 | -- | 23,664,017(+) | GCCCA(A/G)ACAGA | upstream-variant-2KB | |
| rs747838042 | -- | 23,666,539(+) | AGGGG(C/T)TGGGT | intron-variant, upstream-variant-2KB |
Residual Variation Intolerance Score:
37.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.76;
33.30% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for PRDX4 Gene
- Human Gene Mutation Database (HGMD)
- PRDX4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRDX4 Gene
Disorders for PRDX4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| scurvy |
|
|
Search PRDX4 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for PRDX4
No data available for UniProtKB/Swiss-Prot and Genatlas for PRDX4 Gene
Publications for PRDX4 Gene
- Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation. (PMID: 9388242) Jin D.-Y. … Jeang K.-T. (J. Biol. Chem. 1997) 2 3 4 23 67
- TNF-related apoptosis-inducing ligand suppresses PRDX4 expression. (PMID: 19364504) Wang H.Q. … Zhang H.Y. (FEBS Lett. 2009) 3 23
- Peroxiredoxin IV is an endoplasmic reticulum-localized enzyme forming oligomeric complexes in human cells. (PMID: 18052930) Tavender T.J. … Bulleid N.J. (Biochem. J. 2008) 3 23
- Involvement of peroxiredoxin IV in the 16alpha-hydroxyestrone-induced proliferation of human MCF-7 breast cancer cells. (PMID: 18272409) Lee S.U. … Kim S.H. (Cell Biol. Int. 2008) 3 23
- Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry. (PMID: 15952740) Ahmed M. … Bergsten P. (J. Proteome Res. 2005) 3 23
Products for PRDX4 Gene
- R&D Systems Antibodies for PRDX4 (Peroxiredoxin 4)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for PRDX4
- Origene Custom Protein Services for PRDX4
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for PRDX4
- Browse OriGene Inhibitory RNA Products For PRDX4
- OriGene qPCR primer pairs for PRDX4
- OriGene qPCR primer pairs and template standards for PRDX4
- OriGene CRISPR knockouts for PRDX4
- OriGene clones in human for PRDX4
- OriGene ORF clones in human,mouse,rat for PRDX4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for PRDX4
- GenScript Custom Assay Services for PRDX4
- GenScript Custom overexpressing Cell Line Services for PRDX4
- GenScript: Design CRISPR guide RNA sequences for PRDX4
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for PRDX4
- Novus Biologicals Antibodies for PRDX4
- Novus Biologicals proteins and lysates for PRDX4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for PRDX4
- Cloud-Clone Corp. Antibodies for PRDX4
- Cloud-Clone Corp. Proteins for PRDX4
- Cloud-Clone Corp Assay Kits for PRDX4
- antibodies-online Antibodies for PRDX4: See all 104
- antibodies-online Kits for PRDX4: See all 11
- antibodies-online Proteins for PRDX4: See all 27
- Search antibodies-online for peptides
- GeneTex PRDX4 antibody for PRDX4
- Search GeneTex for Proteins for PRDX4
- ViGene Biosciences adenoviral particle packaged cDNA for PRDX4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PRDX4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PRDX4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PRDX4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PRDX4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PRDX4 gene
- Search ViGene Biosciences for PRDX4
- Search ViGene Biosciences for PRDX4
- Santa Cruz Biotechnology (SCBT) Antibodies for PRDX4
- Search Santa Cruz Biotechnology (SCBT) for PRDX4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PRDX4
Sources for PRDX4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon