Aliases for CREB3 Gene
Aliases for CREB3 Gene
- CAMP Responsive Element Binding Protein 3 2 3 5
- Transcription Factor LZIP-Alpha 3 4
- Small Leucine Zipper Protein 2 3
- LUMAN 3 4
- LZIP 3 4
- Cyclic AMP Response Element (CRE)-Binding Protein/Activating Transcription Factor 1 3
- CAMP Responsive Element Binding Protein 3 (Luman) 2
- Cyclic AMP-Responsive Element-Binding Protein 3 3
External Ids for CREB3 Gene
- HGNC: 2347
- Entrez Gene: 10488
- Ensembl: ENSG00000107175
- OMIM: 606443
- UniProtKB: O43889
Previous GeneCards Identifiers for CREB3 Gene
- GC09P036044
- GC09P035901
Summaries for CREB3 Gene
-
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]
GeneCards Summary for CREB3 Gene
CREB3 (CAMP Responsive Element Binding Protein 3) is a Protein Coding gene. Diseases associated with CREB3 include Herpes Simplex. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is CREB3L3.
UniProtKB/Swiss-Prot for CREB3 Gene
-
Endoplasmic reticulum (ER)-bound transcription factor that plays a role in the unfolded protein response (UPR). Involved in cell proliferation and migration, tumor suppression and inflammatory gene expression. Plays also a role in the human immunodeficiency virus type 1 (HIV-1) virus protein expression and in the herpes simplex virus-1 (HSV-1) latent infection and reactivation from latency. Isoform 2 plays a role in the unfolded protein response (UPR). Isoform 2 acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Isoform 2 may play a role as a cellular tumor suppressor that is targeted by the hepatitis C virus (HSV) core protein. Isoform 2 represses the VP16-mediated transactivation of immediate early genes of the HSV-1 virus by sequestring host cell factor-1 HCFC1 in the ER membrane of sensory neurons, thereby preventing the initiation of the replicative cascade leading to latent infection. Isoform 3 functions as a negative transcriptional regulator in ligand-induced transcriptional activation of the glucocorticoid receptor NR3C1 by recruiting and activating histone deacetylases (HDAC1, HDAC2 and HDAC6). Isoform 3 decreases the acetylation level of histone H4. Isoform 3 does not promote the chemotactic activity of leukocyte cells.
-
Processed cyclic AMP-responsive element-binding protein 3: acts as a transcription factor that activates unfolded protein response (UPR) target genes during endoplasmic reticulum (ER) stress response. Promotes cell survival against ER stress-induced apoptotic cell death during UPR. Activates transcription from CRE and C/EBP-containing reporter genes. Induces transcriptional activation of chemokine receptors. Activates transcription of genes required for reactivation of the latent HSV-1 virus. Down-regulates Tat-dependent transcription of the HIV-1 LTR by interacting with HIV-1 Tat. Its transcriptional activity is inhibited by CREBZF in a HCFC1-dependent manner, by the viral transactivator protein VP16 and by the HCV core protein. Binds DNA to the cAMP response element (CRE) (consensus: 5-GTGACGT[AG][AG]-3) and C/EBP sequences present in many viral and cellular promoters. Binds to the unfolded protein respons element (UPRE) consensus sequences sites. Binds DNA to the 5-CCAC[GA]-3half of ERSE II (5-ATTGG-N-CCACG-3). Associates with chromatin to the HERPUD1 promoter.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CREB3 Gene
Genomics for CREB3 Gene
GeneHancer (GH) Regulatory Elements for CREB3 Gene
Promoters and enhancers for CREB3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CREB3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CREB3 Gene
Genomic Locations for CREB3 Gene
- chr9:35,732,320-35,737,008
- (GRCh38/hg38)
- Size:
- 4,689 bases
- Orientation:
- Plus strand
- chr9:35,732,317-35,737,005
- (GRCh37/hg19)
Genomic View for CREB3 Gene
Genes around CREB3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9p13.3 by Ensembl
- 9p13.3 by Entrez Gene
- 9p13.3 by HGNC
CREB3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CREB3 Gene
Proteins for CREB3 Gene
-
Protein details for CREB3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43889-CREB3_HUMAN
- Recommended name:
- Cyclic AMP-responsive element-binding protein 3
- Protein Accession:
- O43889
- D0PTW6
- O14671
- O14919
- Q5TCV1
- Q96GK8
- Q9H2W3
- Q9UE77
Protein attributes for CREB3 Gene
- Size:
- 395 amino acids
- Molecular mass:
- 43917 Da
- Quaternary structure:
-
- Homodimer; homodimerization is prevented by the HCV core protein. Interacts with HCFC1; the interaction is required to stimulate CREB3 transcriptional activity. Isoform 2 interacts with CREBZF; the interaction occurs only in combination with HCFC1. Isoform 2 interacts (via central part and transmembrane region) with TM7SF4 (via C-terminus cytoplasmic domain). Isoform 2 interacts with OS9. Isoform 2 interacts (via leucine-zipper domain) with CREBRF (via leucine-zipper domain); the interaction occurs only after CREB3 activation and promotes CREB3 degradation. Isoform 2 interacts (via C-terminal domain) with CCR1. Isoform 2 interacts (via leucine-zipper and transmembrane domains) with HIV-1 ENV (via cytoplasmic domain). Isoform 2 interacts (via leucine-zipper and transmembrane domains) with HIV-1 TMgp41 (via cytoplasmic domain); the interaction reduces CREB3 stability. Interacts with the HCV core protein. Processed cyclic AMP-responsive element-binding protein 3 interacts with HIV-1 Tat.
Post-translational modifications for CREB3 Gene
- N-glycosylated.
- The ER membrane embedded cyclic AMP-responsive element-binding protein 3 form is first proteolytically cleaved by site-1 protease (S1P) that generates membrane-associated N-terminus and a luminal C-terminus forms. The membrane-associated N-terminus form is further proteolytically processed probably by the site-2 protease (S2P) through a regulated intramembrane proteolysis (RIP), releasing the transcriptional active processed cyclic AMP-responsive element-binding protein 3 form, which is transported to the nucleus. The proteolytic cleavage is strongly induced during dendritic cell (DC) maturation and inhibited by TM7SF4.
- The processed cyclic AMP-responsive element-binding protein 3 is rapidly degraded.
- Ubiquitination at posLast=376376
Other Protein References for CREB3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
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Assay Products
No data available for DME Specific Peptides for CREB3 Gene
Domains & Families for CREB3 Gene
Gene Families for CREB3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transcription factors
Protein Domains for CREB3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CREB3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O43889- Family:
-
- Belongs to the bZIP family. ATF subfamily.
Function for CREB3 Gene
Molecular function for CREB3 Gene
- UniProtKB/Swiss-Prot Function:
- Endoplasmic reticulum (ER)-bound transcription factor that plays a role in the unfolded protein response (UPR). Involved in cell proliferation and migration, tumor suppression and inflammatory gene expression. Plays also a role in the human immunodeficiency virus type 1 (HIV-1) virus protein expression and in the herpes simplex virus-1 (HSV-1) latent infection and reactivation from latency. Isoform 2 plays a role in the unfolded protein response (UPR). Isoform 2 acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Isoform 2 may play a role as a cellular tumor suppressor that is targeted by the hepatitis C virus (HSV) core protein. Isoform 2 represses the VP16-mediated transactivation of immediate early genes of the HSV-1 virus by sequestring host cell factor-1 HCFC1 in the ER membrane of sensory neurons, thereby preventing the initiation of the replicative cascade leading to latent infection. Isoform 3 functions as a negative transcriptional regulator in ligand-induced transcriptional activation of the glucocorticoid receptor NR3C1 by recruiting and activating histone deacetylases (HDAC1, HDAC2 and HDAC6). Isoform 3 decreases the acetylation level of histone H4. Isoform 3 does not promote the chemotactic activity of leukocyte cells.
- UniProtKB/Swiss-Prot Function:
- Processed cyclic AMP-responsive element-binding protein 3: acts as a transcription factor that activates unfolded protein response (UPR) target genes during endoplasmic reticulum (ER) stress response. Promotes cell survival against ER stress-induced apoptotic cell death during UPR. Activates transcription from CRE and C/EBP-containing reporter genes. Induces transcriptional activation of chemokine receptors. Activates transcription of genes required for reactivation of the latent HSV-1 virus. Down-regulates Tat-dependent transcription of the HIV-1 LTR by interacting with HIV-1 Tat. Its transcriptional activity is inhibited by CREBZF in a HCFC1-dependent manner, by the viral transactivator protein VP16 and by the HCV core protein. Binds DNA to the cAMP response element (CRE) (consensus: 5-GTGACGT[AG][AG]-3) and C/EBP sequences present in many viral and cellular promoters. Binds to the unfolded protein respons element (UPRE) consensus sequences sites. Binds DNA to the 5-CCAC[GA]-3half of ERSE II (5-ATTGG-N-CCACG-3). Associates with chromatin to the HERPUD1 promoter.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated upon differentiation of monocytes towards immature dendritic cells (DC). Down-regulated upon DC maturation. Up-regulated by endoplasmic reticulum stress triggered by thapsigargin (Tg) or tunicamycin (Tm). Up-regulated by CCR1-dependent chemokines in an immediate early response and biphasic manner and by NF-kappa-B.
Phenotypes From GWAS Catalog for CREB3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IDA | 16940180 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 16940180 |
| GO:0000982 | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 16940180 |
| GO:0001077 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IMP | 16940180 |
| GO:0003677 | DNA binding | IEA | -- |
Phenotypes for CREB3 Gene
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miRNA for CREB3 Gene
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CREB3 Gene
Localization for CREB3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CREB3 Gene
- Isoform 2: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Membrane. Note=Colocalizes with HCFC1 in neuronal cell bodies of the trigeminal ganglia (By similarity). Colocalizes with TM7SF4 in the ER membrane of immature dendritic cell (DC). Colocalizes with CANX, CCR1, HCFC1 in the ER membrane. Sequestred into the cytoplasm by the HCV core protein. {ECO:0000250}.
- Isoform 3: Nucleus. Cytoplasm. Note=Predominantly in the nucleus.
- Processed cyclic AMP-responsive element-binding protein 3: Nucleus. Note=Upon RIP activation the transcriptional active processed cyclic AMP-responsive element-binding protein 3 form translocates into the nucleus. Detected in the nucleus upon dendritic cell maturation and RIP activation. Colocalizes with CREBRF in nuclear foci. Colocalizes with CREBZF in promyelocytic leukemia protein nuclear bodies (PML-NB).
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| endoplasmic reticulum | 5 |
| cytosol | 5 |
| golgi apparatus | 5 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005634 | nucleus | IC,IDA | 20546900 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IDA | 16236796 |
Pathways & Interactions for CREB3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Aldosterone synthesis and secretion | ||
| 2 | Activation of cAMP-Dependent PKA |
.77
|
.56
|
| 3 | CREB Pathway |
.68
.68
|
|
| 4 | DREAM Repression and Dynorphin Expression |
.44
|
|
| 5 | G-Beta Gamma Signaling |
.46
.44
|
.37
|
Pathways by source for CREB3 Gene
6 Sino Biological pathways for CREB3 Gene
2 BioSystems pathways for CREB3 Gene
27 KEGG pathways for CREB3 Gene
45 Qiagen pathways for CREB3 Gene
Interacting Proteins for CREB3 Gene
Selected Interacting proteins:
O43889-CREB3_HUMAN
ENSP00000342136
for CREB3 Gene via
MINT
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription by RNA polymerase II | IEA | -- |
| GO:0006935 | chemotaxis | IEA | -- |
| GO:0006986 | response to unfolded protein | IEA | -- |
Drugs & Compounds for CREB3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| cyclic amp | Experimental | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for CREB3 Gene
mRNA/cDNA for CREB3 Gene
- (1) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (297) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CREB3 Gene
CRISPR Products
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Expression for CREB3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
NURSA nuclear receptor signaling pathways regulating expression of CREB3 Gene:
CREB3SOURCE GeneReport for Unigene cluster for CREB3 Gene:
Hs.522110mRNA Expression by UniProt/SwissProt for CREB3 Gene:
O43889-CREB3_HUMAN
Tissue specificity:
Expressed in dendritic cells (DC). Weakly expressed in monocytes (at protein level). Ubiquitous.
Evidence on tissue expression from TISSUES for CREB3 Gene
- Nervous system(4.8)
- Pancreas(4.2)
- Skin(4.2)
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No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CREB3 Gene
Orthologs for CREB3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CREB3 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CREB3 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CREB3 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Creb3 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Creb3 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CREB3 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CREB3 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CREB3 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CREB3 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | creb3 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16347 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | creb3l3l 33 34 |
|
||
| wufj05f07 33 |
|
||||
| worm (Caenorhabditis elegans) |
Secernentea | let-607 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for CREB3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CREB3 Gene
Variants for CREB3 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs398123015 | pathogenic, Spastic paraplegia 46, autosomal recessive, Hereditary spastic paraplegia | 35,737,335(+) | C/T | downstream_transcript_variant | |
| rs869025236 | uncertain-significance, Ductal breast carcinoma | 35,736,433(+) | T/G | coding_sequence_variant, missense_variant | |
| rs752274637 | likely-pathogenic, not provided | 35,737,405(+) | G/A | downstream_transcript_variant | |
| rs1000622693 | -- | 35,730,746(+) | T/G | upstream_transcript_variant | |
| rs1000779511 | -- | 35,730,392(+) | T/G | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv25437 | CNV | loss | 19812545 |
| nsv1125318 | OTHER | inversion | 24896259 |
Residual Variation Intolerance Score:
74.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.15;
23.20% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CREB3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CREB3 Gene
Disorders for CREB3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| herpes simplex |
|
Search CREB3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CREB3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CREB3 Gene
Publications for CREB3 Gene
- Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor. (PMID: 9271389) Lu R … Misra V (Molecular and cellular biology 1997) 2 3 4 22 58
- A novel isoform of human LZIP negatively regulates the transactivation of the glucocorticoid receptor. (PMID: 19779205) Kang H … Ko J (Molecular endocrinology (Baltimore, Md.) 2009) 3 4 22 58
- Regulation of human LZIP expression by NF-kappaB and its involvement in monocyte cell migration induced by Lkn-1. (PMID: 17296613) Jang SW … Ko J (The Journal of biological chemistry 2007) 3 4 22 58
- Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. (PMID: 16940180) Liang G … Lu R (Molecular and cellular biology 2006) 3 4 22 58
- Zhangfei is a potent and specific inhibitor of the host cell factor-binding transcription factor Luman. (PMID: 15705566) Misra V … Korchinski P (The Journal of biological chemistry 2005) 3 4 22 58
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- Invitrogen Antibodies for CREB3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CREB3
- antibodies-online: Search results for 78 available CREB3 Antibodies ranked by validation data
- Compare Top CREB3 Antibodies
- antibodies-online: Search results for 2 available CREB3 Elisa Kits ranked by validation data
- Compare Top CREB3 Elisa Kits
- Recommended
- antibodies-online: Search results for 9 available CREB3 Proteins ranked by validation data
- Compare Top CREB3 Proteins
- GeneTex CREB3 antibody for CREB3
- Search GeneTex for Proteins for CREB3
- ViGene Biosciences adenoviral particle packaged cDNA for CREB3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CREB3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CREB3 gene
- Search ViGene Biosciences for CREB3
- Santa Cruz Biotechnology (SCBT) Antibodies for CREB3
- Search Santa Cruz Biotechnology (SCBT) for CREB3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CREB3
- Horizon Cell Lines for CREB3
- genomics-online: cdna clones - Search results for 115 available CREB3 gene related products
- Overview of 115 available CREB3 gene related products
- orf clones - Search results for 115 available CREB3 gene related products
- Overview of 115 available CREB3 gene related products
- genomics-online: gRNA clones - Search results for 115 available CREB3 gene related products
- Overview of 115 available CREB3 gene related products
- genomics-online: primer clones - Search results for 115 available CREB3 gene related products
- Overview of 115 available CREB3 gene related products
- genomics-online: shRNA clones - Search results for 115 available CREB3 gene related products
- Overview of 115 available CREB3 gene related products
Sources for CREB3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew