Free for academic non-profit institutions. Other users need a Commercial license

Aliases for AKR1A1 Gene

Aliases for AKR1A1 Gene

  • Aldo-Keto Reductase Family 1 Member A1 2 3 4 5
  • Aldehyde Reductase 2 3 4
  • Dihydrodiol Dehydrogenase 3 2 3
  • EC 1.1.1.2 4 61
  • ALDR1 3 4
  • ALR 3 4
  • Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) 2
  • Epididymis Secretory Sperm Binding Protein Li 165mP 3
  • Epididymis Secretory Protein Li 6 3
  • Alcohol Dehydrogenase [NADP(+)] 3
  • Alcohol Dehydrogenase 3
  • HEL-S-165mP 3
  • EC 1.1.1 61
  • HEL-S-6 3
  • ARM 3
  • DD3 3

External Ids for AKR1A1 Gene

Previous GeneCards Identifiers for AKR1A1 Gene

  • GC01P045743
  • GC01P045016
  • GC01P045446
  • GC01P045429
  • GC01P045685
  • GC01P045789
  • GC01P046017
  • GC01P044128

Summaries for AKR1A1 Gene

Entrez Gene Summary for AKR1A1 Gene

  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011]

GeneCards Summary for AKR1A1 Gene

AKR1A1 (Aldo-Keto Reductase Family 1 Member A1) is a Protein Coding gene. Diseases associated with AKR1A1 include Ethylene Glycol Poisoning and Fetal Alcohol Syndrome. Among its related pathways are Porphyrin and chlorophyll metabolism and superpathway of tryptophan utilization. GO annotations related to this gene include oxidoreductase activity and alditol:NADP+ 1-oxidoreductase activity. An important paralog of this gene is AKR1B1.

UniProtKB/Swiss-Prot for AKR1A1 Gene

  • Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

Gene Wiki entry for AKR1A1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AKR1A1 Gene

Genomics for AKR1A1 Gene

Regulatory Elements for AKR1A1 Gene

Enhancers for AKR1A1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G045520 1.2 ENCODE 13.3 -28.7 -28683 3.7 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF263 CCDC163 TOE1 PRDX1 GPBP1L1 AKR1A1 ZSWIM5 RPS8 CCDC17 MMACHC PIR60929
GH01G045498 1.1 ENCODE 11.9 -50.6 -50563 3.3 HDGF PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2 CCDC163 PRDX1 TOE1 GPBP1L1 AKR1A1 HMGB1P48 PTCH2 ZSWIM5 RPS8 MMACHC
GH01G045541 1.7 FANTOM5 Ensembl ENCODE 7.4 -6.7 -6693 4.9 HDGF PKNOX1 MLX ZFP64 WRNIP1 ARID4B DMAP1 ZNF48 YY1 ELK1 CCDC163 PRDX1 IPP AKR1A1 MMACHC TESK2 GPBP1L1 TOE1 GC01P045551 HMGB1P48
GH01G045513 0.9 ENCODE 12.5 -36.8 -36832 1.1 FOXA2 ARID4B YY1 ZNF121 FOS MXD4 PPARG KAT8 ZNF592 NFIL3 CCDC163 AKR1A1 MMACHC PIR60929
GH01G045512 0.9 ENCODE 12.5 -37.8 -37770 0.2 HDAC1 PKNOX1 CBX3 ARNT ARID4B SIN3A RAD21 RFX5 ZNF121 EGR1 AKR1A1 PIR60929 CCDC163
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AKR1A1 on UCSC Golden Path with GeneCards custom track

Promoters for AKR1A1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000005866 757 1801 HDGF CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766

Genomic Location for AKR1A1 Gene

Chromosome:
1
Start:
45,550,543 bp from pter
End:
45,570,051 bp from pter
Size:
19,509 bases
Orientation:
Plus strand

Genomic View for AKR1A1 Gene

Genes around AKR1A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AKR1A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AKR1A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AKR1A1 Gene

Proteins for AKR1A1 Gene

  • Protein details for AKR1A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P14550-AK1A1_HUMAN
    Recommended name:
    Alcohol dehydrogenase [NADP(+)]
    Protein Accession:
    P14550
    Secondary Accessions:
    • A8KAL8
    • D3DQ04
    • Q6IAZ4

    Protein attributes for AKR1A1 Gene

    Size:
    325 amino acids
    Molecular mass:
    36573 Da
    Quaternary structure:
    • Monomer.

    Three dimensional structures from OCA and Proteopedia for AKR1A1 Gene

neXtProt entry for AKR1A1 Gene

Selected DME Specific Peptides for AKR1A1 Gene

P14550:
  • RSPAQILLRWQVQRKVICIPKS
  • ALEALVAKGLV
  • VFDFTFSPEEMKQL
  • VTAYSPLGS
  • GYRHIDCA
  • AAIYGNE
  • MPLIGLGT
  • GLGTWKS
  • PDEPVLLEEPVVLALAEK
  • DLYLMHWP

Post-translational modifications for AKR1A1 Gene

  • Ubiquitination at posLast=153153
  • Modification sites at PhosphoSitePlus

Domains & Families for AKR1A1 Gene

Gene Families for AKR1A1 Gene

Protein Domains for AKR1A1 Gene

Suggested Antigen Peptide Sequences for AKR1A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P14550

UniProtKB/Swiss-Prot:

AK1A1_HUMAN :
  • Belongs to the aldo/keto reductase family.
Family:
  • Belongs to the aldo/keto reductase family.
genes like me logo Genes that share domains with AKR1A1: view

Function for AKR1A1 Gene

Molecular function for AKR1A1 Gene

GENATLAS Biochemistry:
aldehyde reductase 1,monomeric NADPH dependent,expressed in many organs predominantly in kidney,cortex,liver,thyroid,small intestine,cytosolic reducing various biogenic and xenobiotic aldehyde compounds,with two alternatively spliced transcripts encoding the same protein
UniProtKB/Swiss-Prot CatalyticActivity:
An alcohol + NADP(+) = an aldehyde + NADPH.
UniProtKB/Swiss-Prot Function:
Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

Enzyme Numbers (IUBMB) for AKR1A1 Gene

Gene Ontology (GO) - Molecular Function for AKR1A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004032 alditol:NADP+ 1-oxidoreductase activity IEA --
GO:0004033 aldo-keto reductase (NADP) activity TAS --
GO:0005515 protein binding IPI 21044950
GO:0008106 alcohol dehydrogenase (NADP+) activity IEA --
GO:0009055 electron carrier activity TAS 2498333
genes like me logo Genes that share ontologies with AKR1A1: view
genes like me logo Genes that share phenotypes with AKR1A1: view

Animal Models for AKR1A1 Gene

MGI Knock Outs for AKR1A1:

Animal Model Products

CRISPR Products

miRNA for AKR1A1 Gene

miRTarBase miRNAs that target AKR1A1

Inhibitory RNA Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for AKR1A1 Gene

Localization for AKR1A1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for AKR1A1 gene
Compartment Confidence
extracellular 5
cytosol 5
nucleus 3
plasma membrane 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for AKR1A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 23580065
GO:0005829 cytosol TAS --
GO:0016324 apical plasma membrane IEA --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with AKR1A1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for AKR1A1 Gene

Pathways & Interactions for AKR1A1 Gene

genes like me logo Genes that share pathways with AKR1A1: view

Gene Ontology (GO) - Biological Process for AKR1A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006006 glucose metabolic process TAS 2498333
GO:0006081 cellular aldehyde metabolic process TAS 2498333
GO:0019640 glucuronate catabolic process to xylulose 5-phosphate TAS --
GO:0019853 L-ascorbic acid biosynthetic process IEA --
GO:0042840 D-glucuronate catabolic process IEA --
genes like me logo Genes that share ontologies with AKR1A1: view

No data available for SIGNOR curated interactions for AKR1A1 Gene

Drugs & Compounds for AKR1A1 Gene

(55) Drugs for AKR1A1 Gene - From: DrugBank, FDA Approved Drugs, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ethanol Approved Pharma Enzyme 2137
Glycerol Approved, Experimental Pharma 238
Zinc Approved Pharma 2296
Doxorubicin Approved, Investigational Pharma Enzyme, substrate Topo II inhibitor,immunosuppresive antineoplastic antibiotic 1751
Doxil Approved June 1999 Pharma DNA intercalator and TOPO II inhibitor, Topoisomerase 2 Inhibitors 1751

(90) Additional Compounds for AKR1A1 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
nadph
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
  • b-NADPH
53-57-6
1-Butanol
  • 1-Butanol
  • 1-Butyl alcohol
  • Butanol
  • Butyl alcohol
  • Butyl hydroxide
71-36-3
1-Hexanol
  • 1-Hexanol
  • 1-Hexyl alcohol
  • 1-Hydroxyhexane
  • Alcohol C-6
  • Alcohol(C6)
111-27-3
1-Pentanol
  • 1-Pentanol
  • 1-Pentol
  • 1-Pentyl alcohol
  • Alcool amylique
  • Alcool amylique (french)
71-41-0
6-Hydroxyhexanoic acid
  • 6-Hydroxyhexanoate
  • 6-Hydroxyhexanoic acid
1191-25-9
genes like me logo Genes that share compounds with AKR1A1: view

Transcripts for AKR1A1 Gene

Unigene Clusters for AKR1A1 Gene

Aldo-keto reductase family 1, member A1 (aldehyde reductase):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for AKR1A1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c ^
SP1: - - -
SP2: - - - - - -
SP3: - - -
SP4: - - -
SP5: -
SP6: - - - - - - -
SP7: - - - - - -
SP8: - - -
SP9: - - - -
SP10: - - - -
SP11: - - - - - - - - -
SP12: - - - - -
SP13: - - - - - - -
SP14: - - - - - -
SP15:
SP16: - - -
SP17: - -
SP18:
SP19: - - - - -

ExUns: 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11
SP1: -
SP2: -
SP3: - - - -
SP4: - - - -
SP5:
SP6:
SP7:
SP8: - - -
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18: - - - -
SP19:

Relevant External Links for AKR1A1 Gene

GeneLoc Exon Structure for
AKR1A1
ECgene alternative splicing isoforms for
AKR1A1

Expression for AKR1A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for AKR1A1 Gene

Protein differential expression in normal tissues from HIPED for AKR1A1 Gene

This gene is overexpressed in Liver, secretome (9.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for AKR1A1 Gene



Protein tissue co-expression partners for AKR1A1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of AKR1A1 Gene:

AKR1A1

SOURCE GeneReport for Unigene cluster for AKR1A1 Gene:

Hs.474584

mRNA Expression by UniProt/SwissProt for AKR1A1 Gene:

P14550-AK1A1_HUMAN
Tissue specificity: Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.

Evidence on tissue expression from TISSUES for AKR1A1 Gene

  • Liver(4.7)
  • Kidney(4.6)
  • Intestine(4.4)
  • Nervous system(3.9)
  • Lung(3.3)
  • Skin(3.3)
  • Eye(2.3)
genes like me logo Genes that share expression patterns with AKR1A1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for AKR1A1 Gene

Orthologs for AKR1A1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for AKR1A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia AKR1A1 34 35
  • 99.59 (n)
cow
(Bos Taurus)
Mammalia AKR1A1 34 35
  • 90.56 (n)
dog
(Canis familiaris)
Mammalia AKR1A1 34 35
  • 90.05 (n)
mouse
(Mus musculus)
Mammalia Akr1a1 34 16 35
  • 87.79 (n)
rat
(Rattus norvegicus)
Mammalia Akr1a1 34
  • 87.59 (n)
oppossum
(Monodelphis domestica)
Mammalia AKR1A1 35
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia AKR1A1 35
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves AKR1A1 34 35
  • 71.79 (n)
lizard
(Anolis carolinensis)
Reptilia AKR1A1 35
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia akr1a1 34
  • 69.18 (n)
Str.11963 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.10170 34
zebrafish
(Danio rerio)
Actinopterygii akr1a1b 34 35
  • 65.62 (n)
Dr.13132 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1439 34
fruit fly
(Drosophila melanogaster)
Insecta CG6084 36
  • 49 (a)
CG6083 36 35
  • 47 (a)
CG2767 36
  • 42 (a)
CG9436 36 35
  • 41 (a)
CG10638 36 35
  • 40 (a)
CG12766 36 35
  • 40 (a)
CG10863 35
  • 40 (a)
OneToMany
ARY 35
  • 31 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y39G8B.1 35
  • 46 (a)
OneToMany
Y39G8B.1a 36
  • 45 (a)
Y39G8B.1b 36
  • 45 (a)
T08H10.1 36 35
  • 41 (a)
C07D8.6 36 35
  • 38 (a)
ZC443.1 36
  • 37 (a)
F53F1.3 36
  • 35 (a)
F53F1.2 36
  • 34 (a)
Y39G8B.2 36 35
  • 34 (a)
C01G5.5 36
  • 31 (a)
C35D10.6 36
  • 31 (a)
K07C5.2 36
  • 31 (a)
C07D8.5 35
  • 28 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GRE3 35
  • 37 (a)
OneToMany
GCY1 37
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G37760 34
  • 51.14 (n)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.3560 34
barley
(Hordeum vulgare)
Liliopsida Hv.12012 34
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC26F1.07 34
  • 49.94 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU04510 34
  • 48.86 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 19 (a)
ManyToMany
CSA.5991 35
  • 15 (a)
ManyToMany
Species where no ortholog for AKR1A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for AKR1A1 Gene

ENSEMBL:
Gene Tree for AKR1A1 (if available)
TreeFam:
Gene Tree for AKR1A1 (if available)

Paralogs for AKR1A1 Gene

Paralogs for AKR1A1 Gene

(11) SIMAP similar genes for AKR1A1 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for AKR1A1 Gene

genes like me logo Genes that share paralogs with AKR1A1: view

Variants for AKR1A1 Gene

Sequence variations from dbSNP and Humsavar for AKR1A1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000042735 -- 45,567,730(+) GCTGA(A/G)GCAGG intron-variant
rs1000104279 -- 45,566,449(+) ACCTC(C/T)ACTGC intron-variant
rs1000185295 -- 45,561,221(+) ATAGT(A/C/G)CAGTT intron-variant
rs1000189368 -- 45,551,675(+) ATTAA(C/T)TCTTC intron-variant
rs1000521210 -- 45,562,725(+) GGCTG(A/G)TCTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AKR1A1 Gene

Variant ID Type Subtype PubMed ID
esv3585910 CNV loss 21293372
esv3893512 CNV gain 25118596
nsv829726 CNV loss 17160897

Variation tolerance for AKR1A1 Gene

Residual Variation Intolerance Score: 59.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.64; 56.70% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for AKR1A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AKR1A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AKR1A1 Gene

Disorders for AKR1A1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for AKR1A1 Gene - From: Novoseek and GeneCards

Disorder Aliases PubMed IDs
ethylene glycol poisoning
fetal alcohol syndrome
  • alcohol-related neurodevelopmental disorder
methanol poisoning
alcohol abuse
  • alcoholism
fetal alcohol spectrum disorder
  • fetal alcohol syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for AKR1A1

Genetic Association Database (GAD)
AKR1A1
Human Genome Epidemiology (HuGE) Navigator
AKR1A1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AKR1A1
genes like me logo Genes that share disorders with AKR1A1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for AKR1A1 Gene

Publications for AKR1A1 Gene

  1. The structural organization of the human aldehyde reductase gene, AKR1A1, and mapping to chromosome 1p33-->p32. (PMID: 10393438) Fujii J. … Taniguchi N. (Cytogenet. Cell Genet. 1999) 2 3 4 22 64
  2. Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma. (PMID: 17149600) Lan Q. … Chanock S. (Hum. Genet. 2007) 3 22 46 64
  3. Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members. (PMID: 10510318) O'Connor T. … Hayes J.D. (Biochem. J. 1999) 3 4 22 64
  4. The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases. (PMID: 2498333) Bohren K.M. … Gabbay K.H. (J. Biol. Chem. 1989) 2 3 4 64
  5. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey L.T. … Malats N. (Eur. Urol. 2010) 3 46 64

Products for AKR1A1 Gene

Sources for AKR1A1 Gene

Content
Loading form....