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Aliases for CEBPZ Gene

Aliases for CEBPZ Gene

  • CCAAT/Enhancer Binding Protein (C/EBP), Zeta 2 3
  • CBF 3 4 6
  • CCAAT-Box-Binding Transcription Factor 3 4
  • CCAAT-Binding Factor 3 4
  • NOC1 3 6
  • CBF2 3 4
  • CCAAT/Enhancer Binding Protein Zeta 3
  • CCAAT/Enhancer-Binding Protein Zeta 3
  • HSP-CBF 3

External Ids for CEBPZ Gene

Previous GeneCards Identifiers for CEBPZ Gene

  • GC02M037403
  • GC02M037340
  • GC02M037428
  • GC02M037168

Summaries for CEBPZ Gene

GeneCards Summary for CEBPZ Gene

CEBPZ (CCAAT/Enhancer Binding Protein (C/EBP), Zeta) is a Protein Coding gene. Diseases associated with CEBPZ include normal pressure hydrocephalus. Among its related pathways are Direct p53 effectors and Gastric cancer network 2.

UniProtKB/Swiss-Prot for CEBPZ Gene

  • Stimulates transcription from the HSP70 promoter

Gene Wiki entry for CEBPZ Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEBPZ Gene

Genomics for CEBPZ Gene

Regulatory Elements for CEBPZ Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CEBPZ Gene

Start:
37,201,612 bp from pter
End:
37,231,713 bp from pter
Size:
30,102 bases
Orientation:
Minus strand

Genomic View for CEBPZ Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CEBPZ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEBPZ Gene

Proteins for CEBPZ Gene

  • Protein details for CEBPZ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q03701-CEBPZ_HUMAN
    Recommended name:
    CCAAT/enhancer-binding protein zeta
    Protein Accession:
    Q03701
    Secondary Accessions:
    • Q8NE75

    Protein attributes for CEBPZ Gene

    Size:
    1054 amino acids
    Molecular mass:
    120974 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAA51924.1; Type=Frameshift; Positions=998; Evidence={ECO:0000305};

neXtProt entry for CEBPZ Gene

Proteomics data for CEBPZ Gene at MOPED

Post-translational modifications for CEBPZ Gene

  • Ubiquitination at Lys314
  • Modification sites at PhosphoSitePlus

Other Protein References for CEBPZ Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CEBPZ Gene

Domains for CEBPZ Gene

Protein Domains for CEBPZ Gene

Suggested Antigen Peptide Sequences for CEBPZ Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q03701

UniProtKB/Swiss-Prot:

CEBPZ_HUMAN :
  • Q03701
Family:
  • Belongs to the CBF/MAK21 family.
genes like me logo Genes that share domains with CEBPZ: view

No data available for Gene Families for CEBPZ Gene

Function for CEBPZ Gene

Molecular function for CEBPZ Gene

UniProtKB/Swiss-Prot Function: Stimulates transcription from the HSP70 promoter

Gene Ontology (GO) - Molecular Function for CEBPZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA 2247079
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA 2247079
GO:0003677 DNA binding TAS 2247079
GO:0005488 binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with CEBPZ: view

Phenotypes for CEBPZ Gene

GenomeRNAi human phenotypes for CEBPZ:
genes like me logo Genes that share phenotypes with CEBPZ: view

Animal Model Products

CRISPR Products

miRNA for CEBPZ Gene

miRTarBase miRNAs that target CEBPZ

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CEBPZ

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for CEBPZ Gene

Localization for CEBPZ Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEBPZ Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CEBPZ Gene COMPARTMENTS Subcellular localization image for CEBPZ gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for CEBPZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with CEBPZ: view

Pathways for CEBPZ Gene

genes like me logo Genes that share pathways with CEBPZ: view

Pathways by source for CEBPZ Gene

2 BioSystems pathways for CEBPZ Gene

Gene Ontology (GO) - Biological Process for CEBPZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006366 transcription from RNA polymerase II promoter TAS 2247079
GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA 2247079
genes like me logo Genes that share ontologies with CEBPZ: view

Compounds for CEBPZ Gene

(4) Novoseek inferred chemical compound relationships for CEBPZ Gene

Compound -log(P) Hits PubMed IDs
abscisic acid 60.5 10
sterol 18.6 2
cycloheximide 10.1 1
tyrosine 0 1
genes like me logo Genes that share compounds with CEBPZ: view

Transcripts for CEBPZ Gene

mRNA/cDNA for CEBPZ Gene

Unigene Clusters for CEBPZ Gene

CCAAT/enhancer binding protein (C/EBP), zeta:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CEBPZ

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CEBPZ

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CEBPZ Gene

No ASD Table

Relevant External Links for CEBPZ Gene

GeneLoc Exon Structure for
CEBPZ
ECgene alternative splicing isoforms for
CEBPZ

Expression for CEBPZ Gene

mRNA expression in normal human tissues for CEBPZ Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CEBPZ Gene

SOURCE GeneReport for Unigene cluster for CEBPZ Gene Hs.135406

genes like me logo Genes that share expressions with CEBPZ: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CEBPZ Gene

Orthologs for CEBPZ Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CEBPZ Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CEBPZ 35
  • 99.37 (n)
  • 98.67 (a)
CEBPZ 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CEBPZ 35
  • 87.85 (n)
  • 85.31 (a)
CEBPZ 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CEBPZ 35
  • 89.95 (n)
  • 88.65 (a)
CEBPZ 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cebpz 35
  • 83.09 (n)
  • 82.2 (a)
Cebpz 16
Cebpz 36
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CEBPZ 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CEBPZ 36
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cebpz 35
  • 82.15 (n)
  • 82.21 (a)
chicken
(Gallus gallus)
Aves CEBPZ 35
  • 68.87 (n)
  • 67.21 (a)
CEBPZ 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CEBPZ 36
  • 64 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.10705 35
tropical clawed frog
(Silurana tropicalis)
Amphibia cebpz 35
  • 65.23 (n)
  • 62.82 (a)
Str.7416 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6779 35
zebrafish
(Danio rerio)
Actinopterygii cebpz 35
  • 62.24 (n)
  • 60.83 (a)
cebpz 36
  • 56 (a)
OneToOne
wufi26d06 35
fruit fly
(Drosophila melanogaster)
Insecta CG7839 36
  • 25 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea CELE_F23B12.7 35
  • 47.32 (n)
  • 36.81 (a)
F23B12.7 36
  • 30 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AER174W 35
  • 41.3 (n)
  • 33.29 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MAK21 35
  • 48.93 (n)
  • 36.75 (a)
MAK21 36
  • 27 (a)
OneToOne
MAK21 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E12519g 35
  • 46.81 (n)
  • 35.19 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU09894 35
  • 46.02 (n)
  • 40.15 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC4F10.09c 35
  • 50.24 (n)
  • 39.55 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToOne
Species with no ortholog for CEBPZ:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CEBPZ Gene

ENSEMBL:
Gene Tree for CEBPZ (if available)
TreeFam:
Gene Tree for CEBPZ (if available)

Paralogs for CEBPZ Gene

No data available for Paralogs for CEBPZ Gene

Variants for CEBPZ Gene

Sequence variations from dbSNP and Humsavar for CEBPZ Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1051930 -- 37,227,488(-) TACAG(C/T)ACAAG intron-variant
rs1137437 -- 37,211,850(+) GGAAC(A/G)CTCTC reference, synonymous-codon
rs1803251 -- 37,227,855(-) TTAAA(C/T)CAAAT synonymous-codon, reference
rs2075215 -- 37,227,122(-) GCATT(A/C)ACACA intron-variant
rs2075216 -- 37,227,114(-) ACAGT(A/T)ACTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CEBPZ Gene

Variant ID Type Subtype PubMed ID
nsv2684 CNV Insertion 18451855

Relevant External Links for CEBPZ Gene

HapMap Linkage Disequilibrium report
CEBPZ

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CEBPZ Gene

Disorders for CEBPZ Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for CEBPZ Gene including...

Search for CEBPZ Gene in MalaCards »

(1) University of Copenhagen DISEASES for CEBPZ Gene

(4) Novoseek inferred disease relationships for CEBPZ Gene

Disease -log(P) Hits PubMed IDs
sclerosis systemic 18.6 1
shock 0 1
colorectal cancer 0 1
tumors 0 1
genes like me logo Genes that share disorders with CEBPZ: view

No data available for UniProtKB/Swiss-Prot for CEBPZ Gene

Publications for CEBPZ Gene

  1. A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter. (PMID: 2247079) Lum L. … Wu B. (Mol. Cell. Biol. 1990) 2 3 4 23
  2. Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression. (PMID: 12534345) Uramoto H. … Kohno K. (Biochem. J. 2003) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for CEBPZ Gene

Sources for CEBPZ Gene

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