Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NR1H3 Gene

Aliases for NR1H3 Gene

  • Nuclear Receptor Subfamily 1 Group H Member 3 2 3 4 5
  • LXRA 3 4
  • Nuclear Receptor Subfamily 1, Group H, Member 3 2
  • Liver X Nuclear Receptor Alpha Variant 1 3
  • Oxysterols Receptor LXR-Alpha 3
  • Liver X Receptor-Alpha 2
  • Liver X Receptor Alpha 4
  • LXR-A 3
  • RLD-1 3

External Ids for NR1H3 Gene

Previous GeneCards Identifiers for NR1H3 Gene

  • GC11P049220
  • GC11P048157
  • GC11P047302
  • GC11P047245
  • GC11P047243
  • GC11P047236
  • GC11P046969

Summaries for NR1H3 Gene

Entrez Gene Summary for NR1H3 Gene

  • The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

GeneCards Summary for NR1H3 Gene

NR1H3 (Nuclear Receptor Subfamily 1 Group H Member 3) is a Protein Coding gene. Diseases associated with NR1H3 include Multiple Sclerosis, Disease Progression, Modifier Of and Cerebrotendinous Xanthomatosis. Among its related pathways are Nuclear Receptors in Lipid Metabolism and Toxicity and Metabolism. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription coactivator activity. An important paralog of this gene is NR1H2.

UniProtKB/Swiss-Prot for NR1H3 Gene

  • Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).

Tocris Summary for NR1H3 Gene

  • Liver X receptors (LXRs) and farnesoid X receptors (FXRs) are members of the steroid analog-activated nuclear receptor subfamily, which form heterodimers with members of the retinoid X receptor family. There are two closely related isoforms of each of these enzymes; alpha and beta.

Gene Wiki entry for NR1H3 Gene

Additional gene information for NR1H3 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NR1H3 Gene

Genomics for NR1H3 Gene

Regulatory Elements for NR1H3 Gene

Enhancers for NR1H3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H047267 1.4 ENCODE dbSUPER 12.1 +22.0 22045 5 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A FEZF1 YY1 ZNF766 ACP2 FNBP4 PACSIN3 NUP160 ENSG00000200090 ENSG00000270060 DDB2 RPS10P19 NR1H3 ARFGAP2
GH11H047277 1.1 ENCODE dbSUPER 12 +29.5 29531 1 HDAC1 TBP PKNOX1 ATF1 TBL1XR1 ARNT BRCA1 RFX5 TCF12 ELK1 ACP2 NR1H3 SLC39A13 PACSIN3 ARFGAP2 FNBP4 LOC101928943 ENSG00000283338
GH11H047336 1.1 ENCODE dbSUPER 11.2 +89.2 89206 1 HDAC1 ATF1 EGR1 ATF7 CREM ZEB2 MTA1 SMARCA4 NR2C1 ZNF24 LOC101928943 MADD NR1H3 MTCH2 MYBPC3 GC11P047345 ENSG00000283338
GH11H047329 0.9 ENCODE dbSUPER 11 +81.9 81851 1 JUN ATF2 GLIS2 POLR2A ZNF366 ZBTB48 GLIS1 ZSCAN5C ATF7 PRDM10 PACSIN3 ACP2 MYBPC3 SLC39A13 LOC101928943 MADD NR1H3 FNBP4 ARFGAP2 ENSG00000283338
GH11H047550 1.7 FANTOM5 ENCODE dbSUPER 4.4 +303.9 303887 3 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF207 NUP160 C1QTNF4 RNU5E-10P ENSG00000231880 AMBRA1 KBTBD4 FNBP4 CELF1 PTPRJ NR1H3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NR1H3 on UCSC Golden Path with GeneCards custom track

Promoters for NR1H3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000039658 600 1401 ZFP64 FEZF1 DMAP1 YY1 ZNF143 SP3 ZC3H11A MEF2D SSRP1 ZNF610

Genomic Location for NR1H3 Gene

Chromosome:
11
Start:
47,248,300 bp from pter
End:
47,269,033 bp from pter
Size:
20,734 bases
Orientation:
Plus strand

Genomic View for NR1H3 Gene

Genes around NR1H3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NR1H3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NR1H3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NR1H3 Gene

Proteins for NR1H3 Gene

  • Protein details for NR1H3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13133-NR1H3_HUMAN
    Recommended name:
    Oxysterols receptor LXR-alpha
    Protein Accession:
    Q13133
    Secondary Accessions:
    • A8K3J9
    • D3DQR1
    • Q8IW13
    • Q96H87

    Protein attributes for NR1H3 Gene

    Size:
    447 amino acids
    Molecular mass:
    50396 Da
    Quaternary structure:
    • Heterodimer of LXRA and RXR. Interacts with CCAR2 (via N-terminus) in a ligand-independent manner. Interacts with SIRT1 and this interaction is inhibited by CCAR2.

    Three dimensional structures from OCA and Proteopedia for NR1H3 Gene

    Alternative splice isoforms for NR1H3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NR1H3 Gene

Post-translational modifications for NR1H3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • R&D Systems Antibodies for NR1H3 (LXR alpha/NR1H3)

No data available for DME Specific Peptides for NR1H3 Gene

Domains & Families for NR1H3 Gene

Gene Families for NR1H3 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Nuclear receptors
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Graphical View of Domain Structure for InterPro Entry

Q13133

UniProtKB/Swiss-Prot:

NR1H3_HUMAN :
  • Belongs to the nuclear hormone receptor family. NR1 subfamily.
Family:
  • Belongs to the nuclear hormone receptor family. NR1 subfamily.
genes like me logo Genes that share domains with NR1H3: view

Function for NR1H3 Gene

Molecular function for NR1H3 Gene

UniProtKB/Swiss-Prot Function:
Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).
UniProtKB/Swiss-Prot Induction:
By 9-cis retinoic acid (9CRA).

Phenotypes From GWAS Catalog for NR1H3 Gene

Gene Ontology (GO) - Molecular Function for NR1H3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IEA --
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding IEA --
GO:0003677 DNA binding IEA,TAS 7744246
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA --
GO:0003707 steroid hormone receptor activity IEA --
genes like me logo Genes that share ontologies with NR1H3: view
genes like me logo Genes that share phenotypes with NR1H3: view

Animal Models for NR1H3 Gene

MGI Knock Outs for NR1H3:

Animal Model Products

  • Taconic Biosciences Mouse Models for NR1H3

CRISPR Products

miRNA for NR1H3 Gene

miRTarBase miRNAs that target NR1H3

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for NR1H3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NR1H3 Gene

Localization for NR1H3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NR1H3 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NR1H3 gene
Compartment Confidence
nucleus 5
cytosol 3
extracellular 2
peroxisome 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for NR1H3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IDA 18511497
GO:0005634 nucleus IDA,IEA 25661920
GO:0005654 nucleoplasm TAS --
GO:0043235 receptor complex IDA 18511497
GO:0090575 RNA polymerase II transcription factor complex IDA,IEA 18511497
genes like me logo Genes that share ontologies with NR1H3: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for NR1H3 Gene

Pathways & Interactions for NR1H3 Gene

genes like me logo Genes that share pathways with NR1H3: view

SIGNOR curated interactions for NR1H3 Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for NR1H3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006366 transcription from RNA polymerase II promoter IEA --
GO:0006367 transcription initiation from RNA polymerase II promoter TAS --
genes like me logo Genes that share ontologies with NR1H3: view

Drugs & Compounds for NR1H3 Gene

(30) Drugs for NR1H3 Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, IUPHAR, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Diacerein Approved, Investigational Pharma Target, inhibitor 0
Atenolol Approved Pharma Antagonist 107
Verapamil Approved Pharma Channel blocker 130
Fexaramine Experimental Pharma Agonist Potent, selective farnesoid X receptor (FXR) agonist 0
(2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID Experimental Pharma Target 0

(9) Additional Compounds for NR1H3 Gene - From: Novoseek and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
DY 268
1609564-75-1
GW 3965 hydrochloride
405911-17-3
WAY 252623
875787-07-8

(5) Tocris Compounds for NR1H3 Gene

Compound Action Cas Number
DY 268 Potent FXR antagonist 1609564-75-1
Fexaramine Potent, selective farnesoid X receptor (FXR) agonist 574013-66-4
GW 3965 hydrochloride Orally active liver X receptor (LXR) agonist 405911-17-3
T 0901317 Potent liver X receptor (LXR) agonist; also CAR inverse agonist 293754-55-9
WAY 252623 Potent LXR agonist 875787-07-8

(6) ApexBio Compounds for NR1H3 Gene

Compound Action Cas Number
Fexaramine 574013-66-4
GW3965 HLXRα/hLXRβ agonist,potent and selective 405911-09-3
GW3965 HCl 405911-17-3
LXR-623 Liver X-receptor agonist 875787-07-8
SR-9243 inverse agonist of LXR 1613028-81-1
T0901317 Liver X receptor agonist,potent and selective 293754-55-9
genes like me logo Genes that share compounds with NR1H3: view

Drug Products

Transcripts for NR1H3 Gene

Unigene Clusters for NR1H3 Gene

Nuclear receptor subfamily 1, group H, member 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for NR1H3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for NR1H3 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e · 3f · 3g · 3h · 3i · 3j ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ·
SP1: - - -
SP2: - - - - -
SP3: - - - - - - - - - - - -
SP4: - - - - - - - - - -
SP5: - - - -
SP6: - - - - -
SP7: - - - - - - - - -
SP8: - - - - - - - - - - - - - - -
SP9: - - - - -
SP10: - - - - -
SP11: - - - - - - - -
SP12: -
SP13: - - - - - -
SP14: - - - -
SP15: - - - -
SP16:
SP17:
SP18: - - - -
SP19: - - -
SP20:
SP21:

ExUns: 9c · 9d · 9e · 9f ^ 10a · 10b · 10c · 10d · 10e · 10f ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b
SP1: -
SP2: - -
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11: - - - -
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:

Relevant External Links for NR1H3 Gene

GeneLoc Exon Structure for
NR1H3
ECgene alternative splicing isoforms for
NR1H3

Expression for NR1H3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NR1H3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NR1H3 Gene

This gene is overexpressed in Liver (x4.2).

Protein differential expression in normal tissues from HIPED for NR1H3 Gene

This gene is overexpressed in Stomach (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NR1H3 Gene



Protein tissue co-expression partners for NR1H3 Gene

NURSA nuclear receptor signaling pathways regulating expression of NR1H3 Gene:

NR1H3

SOURCE GeneReport for Unigene cluster for NR1H3 Gene:

Hs.438863

mRNA Expression by UniProt/SwissProt for NR1H3 Gene:

Q13133-NR1H3_HUMAN
Tissue specificity: Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.

Evidence on tissue expression from TISSUES for NR1H3 Gene

  • Liver(4.6)
  • Nervous system(4.3)
  • Heart(4.2)
  • Gall bladder(2.1)
  • Intestine(2.1)
genes like me logo Genes that share expression patterns with NR1H3: view

Primer Products

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for NR1H3 Gene

Orthologs for NR1H3 Gene

This gene was present in the common ancestor of animals.

Orthologs for NR1H3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NR1H3 33 34
  • 99.63 (n)
dog
(Canis familiaris)
Mammalia NR1H3 33 34
  • 91.5 (n)
cow
(Bos Taurus)
Mammalia NR1H3 33 34
  • 90.31 (n)
rat
(Rattus norvegicus)
Mammalia Nr1h3 33
  • 88.76 (n)
mouse
(Mus musculus)
Mammalia Nr1h3 33 16 34
  • 88.39 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia NR1H3 34
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NR1H3 34
  • 73 (a)
OneToOne
chicken
(Gallus gallus)
Aves LXR 34
  • 77 (a)
OneToOne
NR1H3 33
  • 75.04 (n)
lizard
(Anolis carolinensis)
Reptilia NR1H3 34
  • 76 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii nr1h3 33 34
  • 74 (n)
fruit fly
(Drosophila melanogaster)
Insecta EcR 35 34
  • 40 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.5106 33
Species where no ortholog for NR1H3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NR1H3 Gene

ENSEMBL:
Gene Tree for NR1H3 (if available)
TreeFam:
Gene Tree for NR1H3 (if available)

Paralogs for NR1H3 Gene

Variants for NR1H3 Gene

Sequence variations from dbSNP and Humsavar for NR1H3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs61731956 Pathogenic 47,268,596(+) CCTCC(A/G)GACCC downstream-variant-500B, upstream-variant-2KB, reference, missense
rs1000022350 -- 47,257,992(+) GGGCT(C/G)CAGGT intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000196549 -- 47,257,014(+) CGTGA(A/G)CCACC intron-variant, upstream-variant-2KB
rs1000214685 -- 47,250,638(+) TTTGC(A/C)CCTCT intron-variant, upstream-variant-2KB
rs1000233100 -- 47,256,869(+) GGAAC(C/T)ACAGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for NR1H3 Gene

Variant ID Type Subtype PubMed ID
esv3626200 CNV loss 21293372

Variation tolerance for NR1H3 Gene

Residual Variation Intolerance Score: 24.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.12; 22.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NR1H3 Gene

Human Gene Mutation Database (HGMD)
NR1H3
SNPedia medical, phenotypic, and genealogical associations of SNPs for
NR1H3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NR1H3 Gene

Disorders for NR1H3 Gene

MalaCards: The human disease database

(3) MalaCards diseases for NR1H3 Gene - From: HGMD, ClinVar, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
multiple sclerosis, disease progression, modifier of
  • multiple sclerosis 1
cerebrotendinous xanthomatosis
  • cholestanol storage disease
fatty liver disease
  • alcoholic fatty liver
- elite association - COSMIC cancer census association via MalaCards
Search NR1H3 in MalaCards View complete list of genes associated with diseases

Relevant External Links for NR1H3

Genetic Association Database (GAD)
NR1H3
Human Genome Epidemiology (HuGE) Navigator
NR1H3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NR1H3
genes like me logo Genes that share disorders with NR1H3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NR1H3 Gene

Publications for NR1H3 Gene

  1. Functional and genetic analysis in type 2 diabetes of liver X receptor alleles--a cohort study. (PMID: 19292929) Dahlman I … Steffensen KR (BMC medical genetics 2009) 3 22 45 60
  2. Association between liver X receptor alpha gene polymorphisms and risk of metabolic syndrome in French populations. (PMID: 18209740) Legry V … Meirhaeghe A (International journal of obesity (2005) 2008) 3 22 45 60
  3. The lipoprotein/lipid profile is modulated by a gene-diet interaction effect between polymorphisms in the liver X receptor-alpha and dietary cholesterol intake in French-Canadians. (PMID: 17217555) Robitaille J … Vohl MC (The British journal of nutrition 2007) 3 22 45 60
  4. LXR, a nuclear receptor that defines a distinct retinoid response pathway. (PMID: 7744246) Willy PJ … Mangelsdorf DJ (Genes & development 1995) 2 3 4 60
  5. CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase. (PMID: 25661920) Sakurabashi A … Fujii T (The Journal of steroid biochemistry and molecular biology 2015) 3 4 60

Products for NR1H3 Gene

Sources for NR1H3 Gene

Content
Loading form....