Aliases for CYP4F22 Gene
External Ids for CYP4F22 Gene
Previous GeneCards Identifiers for CYP4F22 Gene
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008]
GeneCards Summary for CYP4F22 Gene
CYP4F22 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 22) is a Protein Coding gene. Diseases associated with CYP4F22 include ichthyosis, congenital, autosomal recessive 5 and cyp4f22-related autosomal recessive congenital ichthyosis. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include electron carrier activity and heme binding. An important paralog of this gene is CYP4F12.