Aliases for IFNG Gene
External Ids for IFNG Gene
Previous GeneCards Identifiers for IFNG Gene
This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.[provided by RefSeq, Nov 2009]
GeneCards Summary for IFNG Gene
IFNG (Interferon, Gamma) is a Protein Coding gene. Diseases associated with IFNG include aplastic anemia and tsc2 angiomyolipomas, renal, modifier of. Among its related pathways are TGF-Beta Pathway and Epstein-Barr virus infection. GO annotations related to this gene include cytokine activity and interferon-gamma receptor binding.
UniProtKB/Swiss-Prot for IFNG Gene
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons