Aliases for COA5 Gene
External Ids for COA5 Gene
Previous Symbols for COA5 Gene
This gene encodes an ortholog of yeast Pet191, which in yeast is a subunit of a large oligomeric complex associated with the mitochondrial inner membrane, and required for the assembly of the cytochrome c oxidase complex. Mutations in this gene are associated with mitochondrial complex IV deficiency, a disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to a severe disease affecting several tissues and organs. [provided by RefSeq, Dec 2011]
GeneCards Summary for COA5 Gene
UniProtKB/Swiss-Prot for COA5 Gene
Involved in an early step of the mitochondrial complex IV assembly process.